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1ZRO
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Crystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose
Descriptor: CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II
Authors:Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L.
Deposit date:2005-05-19
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum.
Cell(Cambridge,Mass.), 122, 2005
1ZRL
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BU of 1zrl by Molmil
Crystal structure of EBA-175 Region II (RII)
Descriptor: CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II
Authors:Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L.
Deposit date:2005-05-19
Release date:2005-08-09
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum.
Cell(Cambridge,Mass.), 122, 2005
3BQK
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BU of 3bqk by Molmil
Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate
Descriptor: Erythrocyte membrane protein 1, GLYCEROL, SULFATE ION
Authors:Higgins, M.K.
Deposit date:2007-12-20
Release date:2008-06-24
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of a chondroitin sulfate-binding domain important in placental malaria.
J.Biol.Chem., 283, 2008
3BQI
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BU of 3bqi by Molmil
Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein
Descriptor: Erythrocyte membrane protein 1, GLYCEROL
Authors:Higgins, M.K.
Deposit date:2007-12-20
Release date:2008-06-24
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of a chondroitin sulfate-binding domain important in placental malaria.
J.Biol.Chem., 283, 2008
3BQL
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BU of 3bql by Molmil
Structure of a chondroitin sulphate binding DBL3X domain from a var2csa encoded PfEMP1 protein
Descriptor: Erythrocyte membrane protein 1, GLYCEROL, SULFATE ION
Authors:Higgins, M.K.
Deposit date:2007-12-20
Release date:2008-06-24
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of a chondroitin sulfate-binding domain important in placental malaria.
J.Biol.Chem., 283, 2008
3CML
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Crystal Structure of the DBL3x domain of the Plasmodium falcipurum VAR2CSA protein
Descriptor: Erythrocyte membrane protein 1
Authors:Singh, K, Gittis, A.G, Nguyen, P, Gowda, D.C, Miller, L.H, Garboczi, D.N.
Deposit date:2008-03-23
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A.
Nat.Struct.Mol.Biol., 15, 2008
3CPZ
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Crystal structure of VAR2CSA DBL3x domain in the presence of dodecasaccharide of CSA
Descriptor: Erythrocyte membrane protein 1, SULFATE ION
Authors:Singh, K, Gittis, A.G, Nguyen, P, Gowda, D.C, Miller, L.H, Garboczi, D.N.
Deposit date:2008-04-01
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A.
Nat.Struct.Mol.Biol., 15, 2008
2WAU
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BU of 2wau by Molmil
Structure of DBL6 epsilon domain from VAR2CSA
Descriptor: ERYTHROCYTE MEMBRANE PROTEIN 1 (PFEMP1)
Authors:Khunrae, P, Higgins, M.K.
Deposit date:2009-02-16
Release date:2009-08-18
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Comparison of Two Cspg-Binding Dbl Domains from the Var2Csa Protein Important in Malaria During Pregnancy.
J.Mol.Biol., 393, 2009
2XU0
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BU of 2xu0 by Molmil
Crystal structure of the NTS-DBL1(alpha-1) domain of the Plasmodium falciparum membrane protein 1 (PfEMP1) from the varO strain.
Descriptor: ERYTHROCYTE MEMBRANE PROTEIN 1, GLYCEROL, MAGNESIUM ION, ...
Authors:Juillerat, A, Lewit-Bentley, A, Guillotte, M, Vigan-Womas, I, Hessler, A, Gangnard, S, England, P, Mercereau-Puijalon, O, Bentley, G.A.
Deposit date:2010-10-14
Release date:2011-04-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure of a Plasmodium Falciparum Pfemp1 Rosetting Domain Reveals a Role for the N-Terminal Segment in Heparin-Mediated Rosette Inhibition.
Proc.Natl.Acad.Sci.USA, 108, 2011
2Y8D
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STRUCTURE OF DBL6 EPSILON DOMAIN FROM VAR2CSA STRAIN FCR3
Descriptor: 2-AMINO-ETHANETHIOL, BENZAMIDINE, ERYTHROCYTE MEMBRANE PROTEIN 1
Authors:Gangnard, S, Ramboarina, S, Lewit-Bentley, A, Bentley, G.A.
Deposit date:2011-02-04
Release date:2012-02-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural and Immunological Correlations between the Variable Blocks of the Var2Csa Domain Dbl6Epsilon from Two Plasmodium Falciparum Parasite Lines.
J.Mol.Biol., 425, 2013
3RRC
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Crystal Structure of Region II from Plasmodium vivax Duffy Binding Protein
Descriptor: 1,2-ETHANEDIOL, Duffy receptor, PHOSPHATE ION
Authors:Tolia, N.H.
Deposit date:2011-04-29
Release date:2011-07-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC.
Nat.Struct.Mol.Biol., 18, 2011
2YK0
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Structure of the N-terminal NTS-DBL1-alpha and CIDR-gamma double domain of the PfEMP1 protein from Plasmodium falciparum varO strain.
Descriptor: ERYTHROCYTE MEMBRANE PROTEIN 1, MAGNESIUM ION, SULFATE ION
Authors:Lewit-Bentley, A, Juillerat, A, Vigan-Womas, I, Guillotte, M, Hessel, A, Raynal, B, Mercereau-Puijalon, O, Bentley, G.A.
Deposit date:2011-05-25
Release date:2012-05-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for the Abo Blood-Group Dependence of Plasmodium Falciparum Rosetting.
Plos Pathog., 8, 2012
3VUV
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BU of 3vuv by Molmil
Crystal structure of the merozoite surface protein MSPDBL2 from P. falciparum bound to zinc
Descriptor: Erythrocyte membrane protein, putative, ZINC ION
Authors:Czabotar, P.E, Hodder, A.N, Clarke, O.B, Lin, C.S, Smith, B.J, Cowman, A.F.
Deposit date:2012-07-09
Release date:2012-08-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.114 Å)
Cite:Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum
J.Biol.Chem., 287, 2012
3VUU
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BU of 3vuu by Molmil
Crystal structure of the merozoite surface protein MSPDBL2 from P. falciparum
Descriptor: CHLORIDE ION, Erythrocyte membrane protein, putative
Authors:Czabotar, P.E, Hodder, A.N, Clarke, O.B, Lin, C.S, Smith, B.J, Cowman, A.F.
Deposit date:2012-07-09
Release date:2012-08-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum
J.Biol.Chem., 287, 2012
4GF2
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BU of 4gf2 by Molmil
Crystal structure of Plasmodium falciparum Erythrocyte Binding Antigen 140 (PfEBA-140/BAEBL)
Descriptor: Erythrocyte binding antigen 140, GLYCEROL
Authors:Lin, D.H, Malpede, B.M, Batchelor, J.D, Tolia, N.H.
Deposit date:2012-08-02
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion.
J.Biol.Chem., 287, 2012
4JNO
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BU of 4jno by Molmil
Crystal structure of Plasmodium falciparum Erythrocyte Binding Antigen 140 (PfEBA-140/BAEBL) Region II in complex with sialyllactose
Descriptor: BAEBL protein, N-acetyl-alpha-neuraminic acid
Authors:Tolia, N.H.
Deposit date:2013-03-15
Release date:2013-03-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular Basis for Sialic Acid-dependent Receptor Recognition by the Plasmodium falciparum Invasion Protein Erythrocyte-binding Antigen-140/BAEBL.
J.Biol.Chem., 288, 2013
4K2U
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BU of 4k2u by Molmil
Crystal structure of PfEBA-175 F1 in complex with R218 antibody Fab fragment
Descriptor: Antibody Heavy Chain, Antibody Light Chain, Erythrocyte binding antigen 175, ...
Authors:Tolia, N.H.
Deposit date:2013-04-09
Release date:2013-06-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175.
Plos Pathog., 9, 2013
4NUU
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BU of 4nuu by Molmil
Heterotrimer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)
Descriptor: Duffy antigen/chemokine receptor, Duffy receptor
Authors:Tolia, N.H.
Deposit date:2013-12-04
Release date:2014-02-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC.
Plos Pathog., 10, 2014
4NUV
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BU of 4nuv by Molmil
Heterotetramer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)
Descriptor: Duffy antigen/chemokine receptor, Duffy receptor, GLYCEROL
Authors:Tolia, N.H.
Deposit date:2013-12-04
Release date:2014-02-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC.
Plos Pathog., 10, 2014
4P1T
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BU of 4p1t by Molmil
Crystal structure of the DBL3X-DBL4epsilon double domain from the extracellular part of VAR2CSA PfEMP1 from Plasmodium falciparum
Descriptor: Erythrocyte membrane protein 1
Authors:Gangnard, S, Dechavanne, S, Srivastava, A, Amirat, F, Gamain, B, Lewit-Bentley, A, Bentley, G.A.
Deposit date:2014-02-27
Release date:2015-03-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the DBL3X-DBL4 epsilon region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactions.
Sci Rep, 5, 2015
4QEX
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Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217
Descriptor: Antibody Heavy Chain, Antibody Light Chain, Erythrocyte-binding antigen-175
Authors:Chen, E, Paing, M.M, Salinas, N, Sim, B.K, Tolia, N.H.
Deposit date:2014-05-19
Release date:2014-06-04
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175.
Plos Pathog., 9, 2013
4YFS
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BU of 4yfs by Molmil
Structure of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for malaria vaccine design
Descriptor: Duffy receptor
Authors:Chen, E, Tolia, N.H.
Deposit date:2015-02-25
Release date:2015-03-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Analysis of the Synthetic Duffy Binding Protein (DBP) Antigen DEKnull Relevant for Plasmodium vivax Malaria Vaccine Design.
Plos Negl Trop Dis, 9, 2015
5F3J
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BU of 5f3j by Molmil
Crystal structure of DBP in complex with inhibitory monoclonal antibody 2D10
Descriptor: Antibody 2D10 single chain variable fragment, Duffy receptor
Authors:Chen, E, Salinas, N.D, Tolia, N.H.
Deposit date:2015-12-02
Release date:2016-05-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.001 Å)
Cite:Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
5MZA
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BU of 5mza by Molmil
The DBLb domain of PF11_0521 PfEMP1 bound to human ICAM-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Erythrocyte membrane protein 1 (PfEMP1), ...
Authors:Lennartz, F, Higgins, M.K.
Deposit date:2017-01-31
Release date:2017-03-22
Last modified:2020-10-07
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.
Cell Host Microbe, 21, 2017
5X6N
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Structure of P. Knowlesi DBL Domain Capable of binding Human Duffy Antigen
Descriptor: Duffy binding protein, SULFATE ION, octyl beta-D-glucopyranoside
Authors:Singh, S.K, Hora, R, Belrhali, H, Chitnis, C, Sharma, A.
Deposit date:2017-02-22
Release date:2017-03-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain
Nature, 439, 2006

 

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