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1SPI
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BU of 1spi by Molmil
CRYSTAL STRUCTURE OF SPINACH CHLOROPLAST FRUCTOSE-1,6-BISPHOSPHATASE AT 2.8 ANGSTROMS RESOLUTION
Descriptor: FRUCTOSE 1,6-BISPHOSPHATASE
Authors:Villeret, V, Huang, S, Zhang, Y, Xue, Y, Lipscomb, W.N.
Deposit date:1994-12-14
Release date:1995-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of spinach chloroplast fructose-1,6-bisphosphatase at 2.8 A resolution.
Biochemistry, 34, 1995
7ZUV
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BU of 7zuv by Molmil
Crystal structure of Chlamydomonas reinhardtii chloroplastic sedoheptulose-1,7-bisphosphatase in reducing conditions
Descriptor: FBPase domain-containing protein, SULFATE ION
Authors:Le Moigne, T, Robert, G.Q, Lemaire, S.D, Henri, J.
Deposit date:2022-05-13
Release date:2023-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Characterization of chloroplast ribulose-5-phosphate-3-epimerase from the microalga Chlamydomonas reinhardtii.
Plant Physiol., 2023
1BK4
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BU of 1bk4 by Molmil
CRYSTAL STRUCTURE OF RABBIT LIVER FRUCTOSE-1,6-BISPHOSPHATASE AT 2.3 ANGSTROM RESOLUTION
Descriptor: MAGNESIUM ION, PROTEIN (FRUCTOSE-1,6-BISPHOSPHATASE), SULFATE ION
Authors:Ghosh, D, Weeks, C.M, Erman, M, Roszak, A.W, Kaiser, R, Jornvall, H.
Deposit date:1998-07-14
Release date:1998-07-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of rabbit liver fructose 1,6-bisphosphatase at 2.3 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
5ZWK
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BU of 5zwk by Molmil
Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with fructose-1,6-bisphophate and AMP
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Yunyuan, H, Zeyuan, G, Junjie, Y, Ping, Y, Jian, W.
Deposit date:2018-05-15
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Location of FBPase catalytic metal binding site: a combined experimental and theoretical study
To Be Published
3FBP
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BU of 3fbp by Molmil
STRUCTURE REFINEMENT OF FRUCTOSE-1,6-BISPHOSPHATASE AND ITS FRUCTOSE 2,6-BISPHOSPHATE COMPLEX AT 2.8 ANGSTROMS RESOLUTION
Descriptor: 2,6-di-O-phosphono-beta-D-fructofuranose, FRUCTOSE 1,6-BISPHOSPHATASE
Authors:Ke, H, Thorpe, C.M, Seaton, B.A, Marcus, F, Lipscomb, W.N.
Deposit date:1990-06-07
Release date:1992-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure refinement of fructose-1,6-bisphosphatase and its fructose 2,6-bisphosphate complex at 2.8 A resolution.
J.Mol.Biol., 212, 1990
4KXP
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BU of 4kxp by Molmil
Crystal Structure of AMP complexes of Porcine Liver Fructose-1,6-bisphosphatase Mutant I10D in T-state
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Iancu, C.V, Mukund, S, Choe, J.-Y, Fromm, H.J, Honzatko, R.B.
Deposit date:2013-05-27
Release date:2013-07-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of Displacement of a Catalytically Essential Loop from the Active Site of Mammalian Fructose-1,6-bisphosphatase.
Biochemistry, 52, 2013
4MJO
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BU of 4mjo by Molmil
Human liver fructose-1,6-bisphosphatase(d-fructose-1,6-bisphosphate, 1-phosphohydrolase) (e.c.3.1.3.11) complexed with the allosteric inhibitor 3
Descriptor: Fructose-1,6-bisphosphatase 1, N-({4-bromo-6-[(methylcarbamoyl)amino]pyridin-2-yl}carbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide
Authors:Ruf, A, Joseph, C, Tetaz, T, Benz, J.
Deposit date:2013-09-04
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Determination of protein-ligand binding constants of a cooperatively regulated tetrameric enzyme using electrospray mass spectrometry.
Acs Chem.Biol., 9, 2014
6LS5
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BU of 6ls5 by Molmil
Structure of human liver FBPase complexed with covalent allosteric inhibitor
Descriptor: 2-(ethyldisulfanyl)-1,3-benzothiazole, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Yunyuan, H, Rongrong, S, Yixiang, X, Shuaishuai, N, Yanliang, R, Jian, L, Jian, W.
Deposit date:2020-01-17
Release date:2020-05-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.031 Å)
Cite:Identification of the New Covalent Allosteric Binding Site of Fructose-1,6-bisphosphatase with Disulfiram Derivatives toward Glucose Reduction.
J.Med.Chem., 63, 2020
6LW2
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BU of 6lw2 by Molmil
The N-arylsulfonyl-indole-2-carboxamide-based inhibitors against fructose-1,6-bisphosphatase
Descriptor: 7-chloranyl-4-[(3-methoxyphenyl)amino]-N-(4-methoxyphenyl)sulfonyl-1-methyl-indole-2-carboxamide, Fructose-1,6-bisphosphatase 1
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2020-02-07
Release date:2020-05-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of N -Arylsulfonyl-Indole-2-Carboxamide Derivatives as Potent, Selective, and Orally Bioavailable Fructose-1,6-Bisphosphatase Inhibitors-Design, Synthesis, In Vivo Glucose Lowering Effects, and X-ray Crystal Complex Analysis.
J.Med.Chem., 63, 2020
7B2O
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BU of 7b2o by Molmil
Crystal structure of Chlamydomonas reinhardtii chloroplastic sedoheptulose-1,7-bisphosphatase
Descriptor: FBPase domain-containing protein
Authors:Le Moigne, T, Lemaire, S.D, Henri, J.
Deposit date:2020-11-27
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Crystal structure of Chlamydomonas reinhardtii chloroplastic sedoheptulose-1,7-bisphosphatas
To Be Published
7WJV
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BU of 7wjv by Molmil
Crystal structure of human liver FBPase complexed with an covalent inhibitor
Descriptor: 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Cao, H, Huang, Y, Ren, Y, Wan, J.
Deposit date:2022-01-08
Release date:2022-07-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.724 Å)
Cite:N -Acylamino Saccharin as an Emerging Cysteine-Directed Covalent Warhead and Its Application in the Identification of Novel FBPase Inhibitors toward Glucose Reduction.
J.Med.Chem., 65, 2022
7WVB
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BU of 7wvb by Molmil
Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state
Descriptor: Fructose-1,6-bisphosphatase 1
Authors:Chen, Y, Zhang, J, Li, C, Cao, Y.
Deposit date:2022-02-10
Release date:2023-02-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state
To Be Published
7NS5
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BU of 7ns5 by Molmil
Structure of yeast Fbp1 (Fructose-1,6-bisphosphatase 1)
Descriptor: Fructose-1,6-bisphosphatase, MAGNESIUM ION, PHOSPHATE ION
Authors:Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
Deposit date:2021-03-05
Release date:2021-05-05
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7NS3
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BU of 7ns3 by Molmil
Substrate receptor scaffolding module of yeast Chelator-GID SR4 E3 ubiquitin ligase bound to Fbp1 substrate
Descriptor: BJ4_G0018240.mRNA.1.CDS.1, Fructose-bisphosphatase, Glucose-induced degradation protein 8, ...
Authors:Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
Deposit date:2021-03-05
Release date:2021-05-05
Last modified:2021-07-07
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7CVN
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BU of 7cvn by Molmil
The N-arylsulfonyl-indole-2-carboxamide-based inhibitors against fructose-1,6-bisphosphatase
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, 4-(3-acetamidophenyl)-N-(4-methoxyphenyl)sulfonyl-7-nitro-1H-indole-2-carboxamide, Fructose-1,6-bisphosphatase 1
Authors:Wang, X, Zhou, J, Xu, B.
Deposit date:2020-08-26
Release date:2020-09-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Design,synthesis,biological evaluation and binding mode analysis of 7-nitro-indole-N-acylarylsulfonamide-based fructose-1,6-bisphosphatase inhibitors
Chinese journal of medicinal chemistry, 30, 2020
1LEV
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BU of 1lev by Molmil
PORCINE KIDNEY FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH AN AMP-SITE INHIBITOR
Descriptor: 3-(2-CARBOXY-ETHYL)-4,6-DICHLORO-1H-INDOLE-2-CARBOXYLIC ACID, 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, ...
Authors:Wright, S.W, Carlo, A.A, Danley, D.E, Hageman, D.L, Karam, G.A, Mansour, M.N, McClure, L.D, Pandit, J, Schulte, G.K, Treadway, J.L, Wang, I.-K, Bauer, P.H.
Deposit date:2002-04-10
Release date:2002-10-16
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site.
Bioorg.Med.Chem.Lett., 13, 2003
1KZ8
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BU of 1kz8 by Molmil
CRYSTAL STRUCTURE OF PORCINE FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH A NOVEL ALLOSTERIC-SITE INHIBITOR
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, FRUCTOSE-1,6-BISPHOSPHATASE, ...
Authors:Wright, S.W, Carlo, A.A, Carty, M.D, Danley, D.E, Hageman, D.L, Karam, G.A, Levy, C.B, Mansour, M.N, Mathiowetz, A.M, McClure, L.D, Nestor, N.B, McPherson, R.K, Pandit, J, Pustilnik, L.R, Schulte, G.K, Soeller, W.C, Treadway, J.L, Wang, I.-K, Bauer, P.H.
Deposit date:2002-02-06
Release date:2002-10-16
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:ANILINOQUINAZOLINE INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE BIND AT A NOVEL ALLOSTERIC SITE: SYNTHESIS, IN VITRO CHARACTERIZATION, AND X-RAY CRYSTALLOGRAPHY
J.MED.CHEM., 45, 2002
5K54
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BU of 5k54 by Molmil
Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state
Descriptor: Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2016-05-23
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.717 Å)
Cite:Structural studies of human muscle FBPase
To Be Published
1YZ0
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BU of 1yz0 by Molmil
R-State AMP Complex Reveals Initial Steps of the Quaternary Transition of Fructose-1,6-bisphosphatase
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase, ...
Authors:Iancu, C.V, Mukund, S, Fromm, H.J, Honzatko, R.B.
Deposit date:2005-02-25
Release date:2005-03-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:R-state AMP complex reveals initial steps of the quaternary transition of fructose-1,6-bisphosphatase.
J.Biol.Chem., 280, 2005
1YXI
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BU of 1yxi by Molmil
R-State AMP Complex Reveals Initial Steps of the Quaternary Transition of Fructose-1,6-bisphosphatase
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ...
Authors:Iancu, C.V, Mukund, S, Fromm, H.J, Honzatko, R.B.
Deposit date:2005-02-21
Release date:2005-03-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:R-state AMP complex reveals initial steps of the quaternary transition of fructose-1,6-bisphosphatase.
J.Biol.Chem., 280, 2005
1YYZ
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BU of 1yyz by Molmil
R-State AMP Complex Reveals Initial Steps of the Quaternary Transition of Fructose-1,6-bisphosphatase
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase, ...
Authors:Iancu, C.V, Mukund, S, Fromm, H.J, Honzatko, R.B.
Deposit date:2005-02-25
Release date:2005-03-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:R-state AMP complex reveals initial steps of the quaternary transition of fructose-1,6-bisphosphatase.
J.Biol.Chem., 280, 2005
5L0A
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BU of 5l0a by Molmil
Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state in complex with fructose-1,6-bisphosphate
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2016-07-27
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Structural studies of human muscle FBPase
To Be Published
5LDZ
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Quadruple space group ambiguity due to rotational and translational non-crystallographic symmetry in human liver fructose-1,6-bisphosphatase
Descriptor: CHLORIDE ION, Fructose-1,6-bisphosphatase 1, SULFATE ION, ...
Authors:Ruf, A, Tetaz, T, Schott, B, Joseph, C, Rudolph, M.G.
Deposit date:2016-06-29
Release date:2016-10-26
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase.
Acta Crystallogr D Struct Biol, 72, 2016
5IZ1
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Physcomitrella patens FBPase
Descriptor: fructose-1,6-bisphosphatase
Authors:Einsle, O, Guetle, D.
Deposit date:2016-03-24
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Chloroplast FBPase and SBPase are thioredoxin-linked enzymes with similar architecture but different evolutionary histories.
Proc.Natl.Acad.Sci.USA, 113, 2016
5K55
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BU of 5k55 by Molmil
Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state in complex with fructose-6-phosphate
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2016-05-23
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.977 Å)
Cite:Structural studies of human muscle FBPase
To Be Published

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