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4JV5

Crystal structures of pseudouridinilated stop codons with ASLs

Functional Information from GO Data
ChainGOidnamespacecontents
B0003723molecular_functionRNA binding
B0003735molecular_functionstructural constituent of ribosome
B0005840cellular_componentribosome
B0006412biological_processtranslation
B0015935cellular_componentsmall ribosomal subunit
B0019843molecular_functionrRNA binding
B0022627cellular_componentcytosolic small ribosomal subunit
B1990904cellular_componentribonucleoprotein complex
C0003676molecular_functionnucleic acid binding
C0003723molecular_functionRNA binding
C0003735molecular_functionstructural constituent of ribosome
C0006412biological_processtranslation
D0003723molecular_functionRNA binding
D0003735molecular_functionstructural constituent of ribosome
D0005840cellular_componentribosome
D0006412biological_processtranslation
D0015935cellular_componentsmall ribosomal subunit
D0019843molecular_functionrRNA binding
D0042274biological_processribosomal small subunit biogenesis
D0046872molecular_functionmetal ion binding
D1990904cellular_componentribonucleoprotein complex
E0003723molecular_functionRNA binding
E0003735molecular_functionstructural constituent of ribosome
E0005737cellular_componentcytoplasm
E0005840cellular_componentribosome
E0006412biological_processtranslation
E0015935cellular_componentsmall ribosomal subunit
E0019843molecular_functionrRNA binding
E0043229cellular_componentintracellular organelle
E1990904cellular_componentribonucleoprotein complex
F0003723molecular_functionRNA binding
F0003735molecular_functionstructural constituent of ribosome
F0005737cellular_componentcytoplasm
F0005840cellular_componentribosome
F0006412biological_processtranslation
F0019843molecular_functionrRNA binding
F0022627cellular_componentcytosolic small ribosomal subunit
F0043229cellular_componentintracellular organelle
F0070181molecular_functionsmall ribosomal subunit rRNA binding
F1990904cellular_componentribonucleoprotein complex
G0000028biological_processribosomal small subunit assembly
G0000049molecular_functiontRNA binding
G0003723molecular_functionRNA binding
G0003729molecular_functionmRNA binding
G0003735molecular_functionstructural constituent of ribosome
G0005840cellular_componentribosome
G0006412biological_processtranslation
G0015935cellular_componentsmall ribosomal subunit
G0019843molecular_functionrRNA binding
G0022627cellular_componentcytosolic small ribosomal subunit
G1990904cellular_componentribonucleoprotein complex
H0003723molecular_functionRNA binding
H0003735molecular_functionstructural constituent of ribosome
H0005737cellular_componentcytoplasm
H0005840cellular_componentribosome
H0006412biological_processtranslation
H0019843molecular_functionrRNA binding
H0022627cellular_componentcytosolic small ribosomal subunit
H0043229cellular_componentintracellular organelle
H1990904cellular_componentribonucleoprotein complex
I0000049molecular_functiontRNA binding
I0003723molecular_functionRNA binding
I0003735molecular_functionstructural constituent of ribosome
I0005737cellular_componentcytoplasm
I0005840cellular_componentribosome
I0006412biological_processtranslation
I0019843molecular_functionrRNA binding
I0043229cellular_componentintracellular organelle
I1990904cellular_componentribonucleoprotein complex
J0000049molecular_functiontRNA binding
J0003723molecular_functionRNA binding
J0003735molecular_functionstructural constituent of ribosome
J0005840cellular_componentribosome
J0006412biological_processtranslation
J0015935cellular_componentsmall ribosomal subunit
J0019843molecular_functionrRNA binding
J1990904cellular_componentribonucleoprotein complex
K0003723molecular_functionRNA binding
K0003735molecular_functionstructural constituent of ribosome
K0005840cellular_componentribosome
K0006412biological_processtranslation
K0019843molecular_functionrRNA binding
K0022627cellular_componentcytosolic small ribosomal subunit
K1990904cellular_componentribonucleoprotein complex
L0000049molecular_functiontRNA binding
L0003723molecular_functionRNA binding
L0003735molecular_functionstructural constituent of ribosome
L0005840cellular_componentribosome
L0006412biological_processtranslation
L0015935cellular_componentsmall ribosomal subunit
L0019843molecular_functionrRNA binding
L1990904cellular_componentribonucleoprotein complex
M0000049molecular_functiontRNA binding
M0003676molecular_functionnucleic acid binding
M0003723molecular_functionRNA binding
M0003735molecular_functionstructural constituent of ribosome
M0005829cellular_componentcytosol
M0005840cellular_componentribosome
M0006412biological_processtranslation
M0015935cellular_componentsmall ribosomal subunit
M0019843molecular_functionrRNA binding
M1990904cellular_componentribonucleoprotein complex
N0003723molecular_functionRNA binding
N0003735molecular_functionstructural constituent of ribosome
N0005737cellular_componentcytoplasm
N0005840cellular_componentribosome
N0006412biological_processtranslation
N0008270molecular_functionzinc ion binding
N0019843molecular_functionrRNA binding
N0043229cellular_componentintracellular organelle
N0046872molecular_functionmetal ion binding
N1990904cellular_componentribonucleoprotein complex
O0003723molecular_functionRNA binding
O0003735molecular_functionstructural constituent of ribosome
O0005737cellular_componentcytoplasm
O0005840cellular_componentribosome
O0006412biological_processtranslation
O0019843molecular_functionrRNA binding
O0022627cellular_componentcytosolic small ribosomal subunit
O0043229cellular_componentintracellular organelle
O1990904cellular_componentribonucleoprotein complex
P0003735molecular_functionstructural constituent of ribosome
P0005737cellular_componentcytoplasm
P0005840cellular_componentribosome
P0006412biological_processtranslation
P0015935cellular_componentsmall ribosomal subunit
P0043229cellular_componentintracellular organelle
P1990904cellular_componentribonucleoprotein complex
Q0003723molecular_functionRNA binding
Q0003735molecular_functionstructural constituent of ribosome
Q0005840cellular_componentribosome
Q0006412biological_processtranslation
Q0019843molecular_functionrRNA binding
Q0022627cellular_componentcytosolic small ribosomal subunit
Q1990904cellular_componentribonucleoprotein complex
R0003735molecular_functionstructural constituent of ribosome
R0005840cellular_componentribosome
R0006412biological_processtranslation
S0003723molecular_functionRNA binding
S0003735molecular_functionstructural constituent of ribosome
S0005840cellular_componentribosome
S0006412biological_processtranslation
S0015935cellular_componentsmall ribosomal subunit
T0003723molecular_functionRNA binding
T0003735molecular_functionstructural constituent of ribosome
T0005829cellular_componentcytosol
T0005840cellular_componentribosome
T0006412biological_processtranslation
T0015935cellular_componentsmall ribosomal subunit
T0019843molecular_functionrRNA binding
T0070181molecular_functionsmall ribosomal subunit rRNA binding
T1990904cellular_componentribonucleoprotein complex
U0005840cellular_componentribosome
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A 1601
ChainResidue
AG1401
AC1402
XPSU4
XA5

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MG A 1603
ChainResidue
AU14
AG15
AA16

site_idAC3
Number of Residues1
DetailsBINDING SITE FOR RESIDUE MG A 1604
ChainResidue
AA768

site_idAC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE MG A 1605
ChainResidue
AG758
AG581

site_idAC5
Number of Residues1
DetailsBINDING SITE FOR RESIDUE MG A 1606
ChainResidue
AG286

site_idAC6
Number of Residues2
DetailsBINDING SITE FOR RESIDUE MG A 1607
ChainResidue
AG576
AC578

site_idAC7
Number of Residues1
DetailsBINDING SITE FOR RESIDUE MG A 1608
ChainResidue
AC536

site_idAC8
Number of Residues1
DetailsBINDING SITE FOR RESIDUE MG A 1610
ChainResidue
AU560

site_idAC9
Number of Residues1
DetailsBINDING SITE FOR RESIDUE MG A 1611
ChainResidue
AG903

site_idBC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE MG A 1613
ChainResidue
AC962
AC1200

site_idBC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MG A 1614
ChainResidue
AA865
AC866
AG1079

site_idBC3
Number of Residues1
DetailsBINDING SITE FOR RESIDUE MG A 1615
ChainResidue
AG1224

site_idBC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ZN D 301
ChainResidue
DCYS9
DCYS12
DCYS26
DCYS31
DALA32

site_idBC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG X 101
ChainResidue
AC518
AG530
LPRO48
XG6

site_idBC6
Number of Residues2
DetailsBINDING SITE FOR RESIDUE MG Y 101
ChainResidue
XG6
YI34

Functional Information from PROSITE/UniProt
site_idPS00054
Number of Residues23
DetailsRIBOSOMAL_S11 Ribosomal protein S11 signature. IrALqaS.GLqVksivDdTPvPHN
ChainResidueDetails
KILE95-ASN117

site_idPS00548
Number of Residues35
DetailsRIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewaaqGrVplHt..LranIDygfalarTtyGvlG
ChainResidueDetails
CALA163-GLY197

site_idPS00632
Number of Residues25
DetailsRIBOSOMAL_S4 Ribosomal protein S4 signature. LEsRLdnvVYRlgfAvSrrqARqLV
ChainResidueDetails
DLEU97-VAL121

site_idPS00057
Number of Residues24
DetailsRIBOSOMAL_S18 Ribosomal protein S18 signature. RDYrn.VevLkrFLSEt.GKIlprRR
ChainResidueDetails
RARG32-ARG55

site_idPS00063
Number of Residues16
DetailsALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. LAKTIKraRIlGLlPF
ChainResidueDetails
RLEU66-PHE81

site_idPS00055
Number of Residues8
DetailsRIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR
ChainResidueDetails
LLYS46-ARG53

site_idPS00056
Number of Residues13
DetailsRIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIiEsRPIS
ChainResidueDetails
QGLY54-SER66

site_idPS00052
Number of Residues27
DetailsRIBOSOMAL_S7 Ribosomal protein S7 signature. DvLvtaFInkimrdGKKnlaarIFydA
ChainResidueDetails
GASP20-ALA46

site_idPS00362
Number of Residues31
DetailsRIBOSOMAL_S15 Ribosomal protein S15 signature. LseHLkvhKkDhhShrgLlmMvgqrrrLlrY
ChainResidueDetails
OLEU39-TYR69

site_idPS00962
Number of Residues12
DetailsRIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VkELLEAGVHFG
ChainResidueDetails
BVAL7-GLY18

site_idPS00585
Number of Residues33
DetailsRIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfrFgAlvVVGDrq.GrVGlGfgkap.EVpl.AV
ChainResidueDetails
EGLY23-VAL55

site_idPS00323
Number of Residues25
DetailsRIBOSOMAL_S19 Ribosomal protein S19 signature. NGKqhvpvyItenmVGhkLGEFapT
ChainResidueDetails
SASN53-THR77

site_idPS00646
Number of Residues14
DetailsRIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ
ChainResidueDetails
MARG88-GLN101

site_idPS00361
Number of Residues16
DetailsRIBOSOMAL_S10 Ribosomal protein S10 signature. ArrsGAqvsGPIpLPT
ChainResidueDetails
JALA27-THR42

site_idPS00053
Number of Residues18
DetailsRIBOSOMAL_S8 Ribosomal protein S8 signature. GiaILSTSkGVLtdreAR
ChainResidueDetails
HGLY108-ARG125

site_idPS01048
Number of Residues10
DetailsRIBOSOMAL_S6 Ribosomal protein S6 signature. GlRRLAYpIA
ChainResidueDetails
FGLY44-ALA53

site_idPS00360
Number of Residues19
DetailsRIBOSOMAL_S9 Ribosomal protein S9 signature. GGGksGQidAiklGiARAL
ChainResidueDetails
IGLY67-LEU85

site_idPS00527
Number of Residues23
DetailsRIBOSOMAL_S14 Ribosomal protein S14 signature. R.CvrcgrarsvyrfFGLCRiCLR
ChainResidueDetails
NARG23-ARG45

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:11866529
ChainResidueDetails
NCYS24
NCYS27
NCYS40
NCYS43

217157

PDB entries from 2024-03-13

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