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4G83

Crystal Structure of p73 DNA-Binding Domain Tetramer bound to a Full Response-Element

Functional Information from GO Data
ChainGOidnamespacecontents
A0000976molecular_functiontranscription cis-regulatory region binding
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
A0006915biological_processapoptotic process
B0000976molecular_functiontranscription cis-regulatory region binding
B0003677molecular_functionDNA binding
B0003700molecular_functionDNA-binding transcription factor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
B0006915biological_processapoptotic process
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 401
ChainResidue
ACYS194
AHIS197
ACYS258
ACYS262

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 401
ChainResidue
BCYS194
BHIS197
BCYS258
BCYS262

Functional Information from PROSITE/UniProt
site_idPS00348
Number of Residues13
DetailsP53 p53 family signature. MCNSSCVGGMNRR
ChainResidueDetails
AMET257-ARG269

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
ACYS194
AHIS197
ACYS258
ACYS262
BCYS194
BHIS197
BCYS258
BCYS262

218196

PDB entries from 2024-04-10

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