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3FAV

Structure of the CFP10-ESAT6 complex from Mycobacterium tuberculosis

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005886cellular_componentplasma membrane
A0009274cellular_componentpeptidoglycan-based cell wall
A0044165cellular_componenthost cell endoplasmic reticulum
A0044228cellular_componenthost cell surface
A0044315biological_processprotein secretion by the type VII secretion system
A0046812molecular_functionhost cell surface binding
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0009274cellular_componentpeptidoglycan-based cell wall
B0016020cellular_componentmembrane
B0020002cellular_componenthost cell plasma membrane
B0030430cellular_componenthost cell cytoplasm
B0033644cellular_componenthost cell membrane
B0042803molecular_functionprotein homodimerization activity
B0044165cellular_componenthost cell endoplasmic reticulum
B0044228cellular_componenthost cell surface
B0044315biological_processprotein secretion by the type VII secretion system
B0046812molecular_functionhost cell surface binding
B0052027biological_processsymbiont-mediated perturbation of host signal transduction pathway
B0052085biological_processsymbiont-mediated suppression of host T-cell mediated immune response
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005886cellular_componentplasma membrane
C0009274cellular_componentpeptidoglycan-based cell wall
C0044165cellular_componenthost cell endoplasmic reticulum
C0044228cellular_componenthost cell surface
C0044315biological_processprotein secretion by the type VII secretion system
C0046812molecular_functionhost cell surface binding
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0009274cellular_componentpeptidoglycan-based cell wall
D0016020cellular_componentmembrane
D0020002cellular_componenthost cell plasma membrane
D0030430cellular_componenthost cell cytoplasm
D0033644cellular_componenthost cell membrane
D0042803molecular_functionprotein homodimerization activity
D0044165cellular_componenthost cell endoplasmic reticulum
D0044228cellular_componenthost cell surface
D0044315biological_processprotein secretion by the type VII secretion system
D0046812molecular_functionhost cell surface binding
D0052027biological_processsymbiont-mediated perturbation of host signal transduction pathway
D0052085biological_processsymbiont-mediated suppression of host T-cell mediated immune response
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ZN A 101
ChainResidue
AGLU14
AASN17
AHOH167
BLYS38
BHOH132

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE ZN A 102
ChainResidue
AASP24
AHOH303

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ZN B 1
ChainResidue
BHOH308
BHIS26
BASP30

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 96
ChainResidue
BGLU31
BGLU31
BIMD97
BIMD97

site_idAC5
Number of Residues7
DetailsBINDING SITE FOR RESIDUE IMD B 97
ChainResidue
AARG20
AHOH302
BLEU28
BGLU31
BGLU31
BZN96
BZN96

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN C 101
ChainResidue
BGLU49
CGLU3
CASP7
CHOH306

site_idAC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN C 102
ChainResidue
CASP30
CHOH197
CHOH288
DASP30

site_idAC8
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ZN D 96
ChainResidue
CGLU33
CHOH201
DHIS26

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues136
DetailsTRANSMEM: Helical => ECO:0000305|PubMed:25645924
ChainResidueDetails
BILE11-TRP43
BGLU49-SER85
DILE11-TRP43
DGLU49-SER85

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N-acetylthreonine; partial => ECO:0000269|PubMed:15378760, ECO:0007744|PubMed:21969609
ChainResidueDetails
BTHR2
DTHR2

218500

PDB entries from 2024-04-17

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