PDB keyword search results

1U6D
CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN KEAP1
Descriptor:kelch-like ECH-associated protein 1
Authors:Li, X., Zhang, D., Hannink, M., Beamer, L.J.
Deposit date:2004-07-29
Release date:2004-10-12
Modification date:2009-02-24
Cite:Crystal structure of the kelch domain of human keap1
J.Biol.Chem., 279, 2004
1X2J
STRUCTURAL BASIS FOR THE DEFECTS OF HUMAN LUNG CANCER SOMATIC MUTATIONS IN THE REPRESSION ACTIVITY OF KEAP1 ON NRF2
Descriptor:Kelch-like ECH-associated protein 1
Authors:Padmanabhan, B., Tong, K.I., Nakamura, Y., Ohta, T., Scharlock, M., Kobayashi, A., Ohtsuji, M., Kang, M.-I., Yamamoto, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-04-25
Release date:2006-03-07
Modification date:2009-02-24
Cite:Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Mol.Cell, 21, 2006
1X2R
STRUCTURAL BASIS FOR THE DEFECTS OF HUMAN LUNG CANCER SOMATIC MUTATIONS IN THE REPRESSION ACTIVITY OF KEAP1 ON NRF2
Descriptor:Kelch-like ECH-associated protein 1/Nuclear factor erythroid 2 related factor 2
Authors:Padmanabhan, B., Tong, K.I., Nakamura, Y., Ohta, T., Scharlock, M., Kobayashi, A., Ohtsuji, M., Kang, M.-I., Yamamoto, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-04-26
Release date:2006-03-07
Modification date:2009-02-24
Cite:Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Mol.Cell, 21, 2006
1ZGK
1.35 ANGSTROM STRUCTURE OF THE KELCH DOMAIN OF KEAP1
Descriptor:Kelch-like ECH-associated protein 1
Authors:Li, X., Bottoms, C.A., Hannink, M., Beamer, L.J.
Deposit date:2005-04-21
Release date:2005-10-04
Modification date:2009-02-24
Cite:Conserved solvent and side-chain interactions in the 1.35 Angstrom structure of the Kelch domain of Keap1.
Acta Crystallogr.,Sect.D, 61, 2005
2DYH
CRYSTAL STRUCTURE OF THE KEAP1 PROTEIN IN COMPLEXED WITH THE N-TERMINAL REGION OF THE NRF2 TRANSCRIPTION FACTOR
Descriptor:Kelch-like ECH-associated protein 1, Nrf2/Neh2 peptide from Nuclear factor erythroid 2-related factor 2
Authors:Padmanabhan, B., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-09-14
Release date:2007-09-04
Modification date:2009-02-24
Cite:Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response
Mol.Cell.Biol., 27, 2007
2FLU
CRYSTAL STRUCTURE OF THE KELCH-NEH2 COMPLEX
Descriptor:Kelch-like ECH-associated protein 1, Nrf2
Authors:Li, X., Lo, J., Beamer, L., Hannink, M.
Deposit date:2006-01-06
Release date:2006-08-15
Modification date:2011-07-13
Cite:Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.
Embo J., 25, 2006
2UVK
STRUCTURE OF YJHT
Descriptor:YJHT
Authors:Muller, A., Severi, E., Wilson, K.S., Thomas, G.H.
Deposit date:2007-03-12
Release date:2007-12-04
Modification date:2009-10-13
Cite:Sialic Acid Mutarotation is Catalyzed by the Escherichia Coli Beta-Propeller Protein Yjht.
J.Biol.Chem., 283, 2008
2VPJ
CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN KLHL12
Descriptor:KELCH-LIKE PROTEIN 12
Authors:Keates, T., Pike, A.C.W., Bullock, A.N., Salah, E., Filippakopoulos, P., Roos, A.K., von Delft, F., Savitsky, P., Weigelt, J., Edwards, A., Arrowsmith, C.H., Bountra, C., Knapp, S.
Deposit date:2008-02-29
Release date:2008-03-18
Modification date:2013-03-27
Cite:Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
J.Biol.Chem., 288, 2013
2WOZ
THE NOVEL BETA-PROPELLER OF THE BTB-KELCH PROTEIN KRP1 PROVIDES THE BINDING SITE FOR LASP-1 THAT IS NECESSARY FOR PSEUDOPODIA EXTENSION
Descriptor:KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 10
Authors:Gray, C.H., Mcgarry, L.C., Spence, H.J., Riboldi-Tunnicliffe, A., Ozanne, B.W.
Deposit date:2009-07-31
Release date:2009-09-01
Modification date:2011-07-13
Cite:The Novel Beta-Propeller of the Btb-Kelch Protein Krp1 Provides the Binding Site for Lasp-1 that is Necessary for Pseudopodia Extension.
J.Biol.Chem., 284, 2009
2XN4
CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN KLHL2 (MAYVEN)
Descriptor:KELCH-LIKE PROTEIN 2
Authors:Canning, P., Hozjan, V., Cooper, C.D.O., Ayinampudi, V., Vollmar, M., Pike, A.C.W., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N.
Deposit date:2010-07-30
Release date:2010-08-18
Modification date:2013-03-27
Cite:Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
J.Biol.Chem., 288, 2013
2Z32
CRYSTAL STRUCTURE OF KEAP1 COMPLEXED WITH PROTHYMOSIN ALPHA
Descriptor:Kelch-like ECH-associated protein 1, Prothymosin alpha
Authors:Padmanabhan, B., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-31
Release date:2008-03-11
Modification date:2009-02-24
Cite:Structural analysis of the complex of Keap1 with a prothymosin alpha peptide
Acta Crystallogr.,Sect.F, 64, 2008
3ADE
CRYSTAL STRUCTURE OF KEAP1 IN COMPLEX WITH SEQUESTOSOME-1/P62
Descriptor:Kelch-like ECH-associated protein 1, Sequestosome-1
Authors:Kurokawa, H., Yamamoto, M.
Deposit date:2010-01-19
Release date:2010-03-16
Cite:The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
Nat.Cell Biol., 12, 2010
3II7
CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN KLHL7
Descriptor:Kelch-like protein 7
Authors:Chaikuad, A., Thangaratnarajah, C., Cooper, C.D.O., Ugochukwu, E., Muniz, J.R.C., Krojer, T., Sethi, R., Pike, A.C.W., Filippakopoulos, P., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Bullock, A., Structural Genomics Consortium (SGC)
Deposit date:2009-07-31
Release date:2009-08-25
Modification date:2011-07-13
Cite:Crystal structure of the kelch domain of human KLHL7
To be Published
3VNG
CRYSTAL STRUCTURE OF KEAP1 IN COMPLEX WITH SYNTHETIC SMALL MOLECULAR BASED ON A CO-CRYSTALLIZATION
Descriptor:Kelch-like ECH-associated protein 1
Authors:Kunishima, N., Tanaka, T., Satoh, M., Saburi, H.
Deposit date:2012-01-12
Release date:2013-01-16
Cite:Crystal Structure of Keap1 in Complex with Synthetic Small Molecular based on a co-crystallization
To be Published
3VNH
CRYSTAL STRUCTURE OF KEAP1 SOAKED WITH SYNTHETIC SMALL MOLECULAR
Descriptor:Kelch-like ECH-associated protein 1
Authors:Kunishima, N., Tanaka, T., Satoh, M., Saburi, H.
Deposit date:2012-01-12
Release date:2013-01-16
Cite:Crystal Structure of Keap1 Soaked with Synthetic Small Molecular
To be Published
3ZGC
CRYSTAL STRUCTURE OF THE KEAP1-NEH2 COMPLEX
Descriptor:KELCH-LIKE ECH-ASSOCIATED PROTEIN 1, NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2
Authors:Hoerer, S., Reinert, D., Ostmann, K., Hoevels, Y., Nar, H.
Deposit date:2012-12-17
Release date:2013-06-12
Cite:Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
Acta Crystallogr.,Sect.F, 69, 2013
3ZGD
CRYSTAL STRUCTURE OF A KEAP1 MUTANT
Descriptor:KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
Authors:Hoerer, S., Reinert, D., Ostmann, K., Hoevels, Y., Nar, H.
Deposit date:2012-12-17
Release date:2013-06-12
Cite:Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
Acta Crystallogr.,Sect.F, 69, 2013
4ASC
CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN KBTBD5
Descriptor:KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 5
Authors:Canning, P., Ayinampudi, V., Krojer, T., Strain-Damerell, C., Raynor, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N., Structural Genomics Consortium, (SGC)
Deposit date:2012-04-30
Release date:2012-05-09
Modification date:2013-03-27
Cite:Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
J.Biol.Chem., 288, 2013
4IN4
CRYSTAL STRUCTURE OF CPD 15 BOUND TO KEAP1 KELCH DOMAIN
Descriptor:Kelch-like ECH-associated protein 1
Authors:Silvian, L., Marcotte, D.
Deposit date:2013-01-03
Release date:2013-05-15
Modification date:2013-07-03
Cite:Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism.
Bioorg.Med.Chem., 21, 2013
4IQK
CRYSTAL STRUCTURE OF CPD 16 BOUND TO KEAP1 KELCH DOMAIN
Descriptor:Kelch-like ECH-associated protein 1
Authors:Silvian, L., Marcotte, D.
Deposit date:2013-01-11
Release date:2013-05-15
Modification date:2013-07-03
Cite:Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism.
Bioorg.Med.Chem., 21, 2013
3WDZ
CRYSTAL STRUCTURE OF KEAP1 IN COMPLEX WITH PHOSPHORYLATED P62
Descriptor:Kelch-like ECH-associated protein 1, Peptide from Sequestosome-1
Authors:Fukutomi, T., Takagi, K., Mizushima, T., Tanaka, K., Komatsu, M., Yamamoto, M.
Deposit date:2013-06-26
Release date:2013-09-04
Modification date:2013-12-25
Cite:Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.
Mol.Cell, 51, 2013
4IFL
CRYSTAL STRUCTURES OF APO KEAP1, KEAP1-PEPTIDE, AND KEAP1-COMPOUND COMPLEXES
Descriptor:CRYSTAL STRUCTURE OF THE KELCH-NEH2 COMPLEX
Authors:Pan, H., Lin, M., Yang, Y., Callaway, K., Baker, J., Diep, L., Yan, J., Tanaka, K., Zhu, Y.L., Konradi, A.W., Jobling, M., Tam, D., Ren, Z., Cheung, H., Bova, M., Riley, B.E., Yao, N., Artis, D.R.
Deposit date:2012-12-14
Release date:2013-12-18
Cite:Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes
Acta Crystallogr.,Sect.D
4IFN
CRYSTAL STRUCTURES OF APO KEAP1, KEAP1-PEPTIDE, AND KEAP1-COMPOUND COMPLEXES
Descriptor:kelch-like ECH-associated protein 1
Authors:Pan, H., Lin, M., Yang, Y., Callaway, K., Baker, J., Diep, L., Yan, J., Tanaka, K., Zhu, Y.L., Konradi, A.W., Jobling, M., Tam, D., Ren, Z., Cheung, H., Bova, M., Riley, B.E., Yao, N., Artis, D.R.
Deposit date:2012-12-14
Release date:2013-12-18
Cite:Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes
Acta Crystallogr.,Sect.D
3WN7
CRYSTAL STRUCTURE OF KEAP1 IN COMPLEX WITH THE N-TERMINAL REGION OF THE NRF2 TRANSCRIPTION FACTOR
Descriptor:Kelch-like ECH-associated protein 1, Peptide from Nuclear factor erythroid 2-related factor 2
Authors:Fukutomi, T., Takagi, K., Mizushima, T., Ohuchi, N., Yamamoto, M.
Deposit date:2013-12-05
Release date:2013-12-25
Cite:Kinetic, Thermodynamic and Structural Characterizations of Association between Nrf2-DLGex Degron and Keap1
To be Published
4CH9
CRYSTAL STRUCTURE OF THE HUMAN KLHL3 KELCH DOMAIN IN COMPLEX WITH A WNK4 PEPTIDE
Descriptor:KELCH-LIKE PROTEIN 3, SERINE/THREONINE-PROTEIN KINASE WNK4 (E.C.2.7.11.1)
Authors:Sorrell, F.J., Schumacher, F.R., Kurz, T., Alessi, D.R., Newman, J., Goubin, S., Chalk, R., Kopec, J., Tallant, C., Williams, E., Krojer, T., Von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.
Deposit date:2013-11-29
Release date:2014-01-08
Cite:Crystal Structure of the Human Klhl3 Kelch Domain in Complex with a Wnk4 Peptide
To be Published
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