PDB keyword search results

3E7S
STRUCTURE OF BOVINE ENOS OXYGENASE DOMAIN WITH INHIBITOR AR-C95791
Descriptor:Nitric oxide synthase, endothelial (E.C.1.14.13.39)
Authors:Garcin, E.D., Arvai, A.S., Rosenfeld, R.J., Kroeger, M.D., Crane, B.R., Andersson, G., Andrews, G., Hamley, P.J., Mallinder, P.R., Nicholls, D.J., St-Gallay, S.A., Tinker, A.C., Gensmantel, N.P., Mete, A., Cheshire, D.R., Connolly, S., Stuehr, D.J., Aberg, A., Wallace, A.V., Tainer, J.A., Getzoff, E.D.
Deposit date:2008-08-18
Release date:2008-10-07
Modification date:2009-06-09
Cite:Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
1D0C
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 3-BROMO-7-NITROINDAZOLE (H4B FREE)
Descriptor:BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN (E.C.1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-09-09
Release date:2001-11-21
Modification date:2011-07-13
Cite:Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism.
Biochemistry, 40, 2001
1D0O
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 3-BROMO-7-NITROINDAZOLE (H4B PRESENT)
Descriptor:BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME (E.C.1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-09-13
Release date:2001-11-21
Modification date:2011-07-13
Cite:Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism.
Biochemistry, 40, 2001
1D1V
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH S-ETHYL-N-PHENYL-ISOTHIOUREA (H4B BOUND)
Descriptor:BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME (E.C.1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-09-21
Release date:2001-07-25
Modification date:2011-07-13
Cite:Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.
J.Biol.Chem., 276, 2001
1D1W
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 2-AMINOTHIAZOLINE (H4B BOUND)
Descriptor:BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN (1.14.13.39)
Authors:Li, H., Raman, C.S., Martasek, P., Kral, V., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-09-21
Release date:2000-10-25
Modification date:2011-07-13
Cite:Mapping the active site polarity in structures of endothelial nitric oxide synthase heme domain complexed with isothioureas.
J.Inorg.Biochem., 81, 2000
1D1X
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1,4-PBITU (H4B BOUND)
Descriptor:BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN (1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-09-21
Release date:2001-07-25
Modification date:2011-07-13
Cite:Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.
J.Biol.Chem., 276, 2001
1D1Y
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1,3-PBITU (H4B FREE)
Descriptor:BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN (1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-09-21
Release date:2001-07-25
Modification date:2011-07-13
Cite:Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.
J.Biol.Chem., 276, 2001
1DD7
MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN (DELTA 114) (N-[(1,3-BENZODIOXOL-5-YL)METHYL]-1-[2-(1H-IMIDAZOL-1-YL)PYRIMIDIN-4-YL]-4-(METHOXYCARBONYL)-PIPERAZINE-2-ACETAMIDE COMPLEX
Descriptor:INDUCIBLE NITRIC OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Adler, M., Whitlow, M.
Deposit date:1999-11-08
Release date:2000-03-29
Modification date:2009-02-24
Cite:Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry.
Proc.Natl.Acad.Sci.USA, 97, 2000
1DF1
MURINE INOSOXY DIMER WITH ISOTHIOUREA BOUND IN THE ACTIVE SITE
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Crane, B.R., Rosenfeld, R.J., Arvai, A.S., Ghosh, D.K., Ghosh, S., Tainer, J.A., Stuehr, D.J., Getzoff, E.D.
Deposit date:1999-11-16
Release date:1999-12-08
Modification date:2011-07-13
Cite:N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization.
EMBO J., 18, 1999
1DM6
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH N-(4-CHLOROPHENYL)-N'-HYDROXYGUANIDINE (H4B FREE)
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39) (HEME DOMAIN)
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-12-13
Release date:2000-12-13
Modification date:2011-07-13
Cite:Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism.
Biochemistry, 40, 2001
1DM7
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH HOMOARGININE (H4B FREE)
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39) (HEME DOMAIN)
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-12-13
Release date:2000-12-13
Modification date:2011-07-13
Cite:Crystal Structures of Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed With Various Inhibitors
To be Published
1DM8
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1,2,4-TRIAZOLE-CARBOXAMIDINE (H4B BOUND)
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39) (HEME DOMAIN)
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-12-13
Release date:2000-12-13
Modification date:2011-07-13
Cite:Crystal Structures of Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed With Various Inhibitors
To be Published
1DMI
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 6S-H4B
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39) (HEME DOMAIN)
Authors:Raman, C.S., Li, H., Martasek, P., Kotsonis, P., Pfleiderer, W., Schmidt, H.H.H.W., Masters, B.S.S., Poulos, T.L.
Deposit date:1999-12-14
Release date:2000-12-20
Modification date:2011-07-13
Cite:Crystal Structures of Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with the Pterin Analogues
To be Published
1DMJ
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 5,6-CYCLIC-TETRAHYDROPTERIDINE
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39) (HEME DOMAIN)
Authors:Kotsonis, P., Frohlich, L.G., Raman, C.S., Li, H., Berg, M., Gerwig, R., Groehn, V., Kang, Y., Al-Masoudi, N., Taghavi-Moghadam, S., Mohr, D., Munch, U., Schnabel, J., Martasek, P., Masters, B.S., Strobel, H., Poulos, T., Matter, H., Pfleiderer, W., Schmidt, H.H.
Deposit date:1999-12-14
Release date:2000-12-20
Modification date:2011-07-13
Cite:Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
J.Biol.Chem., 276, 2001
1DMK
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 4-AMINO-6-PHENYL-TETRAHYDROPTERIDINE
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39) (HEME DOMAIN)
Authors:Kotsonis, P., Frohlich, L.G., Raman, C.S., Li, H., Berg, M., Gerwig, R., Groehn, V., Kang, Y., Al-Masoudi, N., Taghavi-Moghadam, S., Mohr, D., Munch, U., Schnabel, J., Martasek, P., Masters, B.S., Strobel, H., Poulos, T., Matter, H., Pfleiderer, W., Schmidt, H.H.
Deposit date:1999-12-14
Release date:2000-12-20
Modification date:2011-07-13
Cite:Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
J.Biol.Chem., 276, 2001
1DWV
MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER N-HYDROXYARGININE AND 4-AMINO TETRAHYDROBIOPTERIN
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Crane, B.R., Arvai, A.S., Getzoff, E.D., Stuehr, D.J., Tainer, J.A.
Deposit date:1999-12-14
Release date:2000-02-06
Modification date:2009-06-16
Cite:Structures of the N(Omega)-Hydroxy-L-Arginine Complex of Inducible Nitric Oxide Synthase Oxygenase Dimer with Active Andinactive Pterins
Biochemistry, 39, 2000
1DWW
MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER N-HYDROXYARGININE AND DIHYDROBIOPTERIN
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Crane, B.R., Arvai, A.S., Getzoff, E.D., Stuehr, D.J., Tainer, J.A.
Deposit date:1999-12-14
Release date:2000-02-06
Modification date:2009-06-16
Cite:Structures of the N(Omega)-Hydroxy-L-Arginine Complex of Inducible Nitric Oxide Synthase Oxygenase Dimer with Active Andinactive Pterins
Biochemistry, 39, 2000
1DWX
MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER N-HYDROXYARGININE AND TETRAHYDROBIOPTERIN
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Crane, B.R., Arvai, A.S., Getzoff, E.D., Stuehr, D.J., Tainer, J.A.
Deposit date:1999-12-14
Release date:2000-02-06
Modification date:2009-06-16
Cite:Structures of the N(Omega)-Hydroxy-L-Arginine Complex of Inducible Nitric Oxide Synthase Oxygenase Dimer with Active Andinactive Pterins
Biochemistry, 39, 2000
1ED4
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH IPITU (H4B FREE)
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Kral, V., Masters, B.S.S., Poulos, T.L.
Deposit date:2000-01-26
Release date:2000-10-25
Modification date:2011-07-13
Cite:Mapping the active site polarity in structures of endothelial nitric oxide synthase heme domain complexed with isothioureas.
J.Inorg.Biochem., 81, 2000
1ED5
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH NNA(H4B FREE)
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:2000-01-26
Release date:2001-01-31
Modification date:2011-07-13
Cite:Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism.
Biochemistry, 40, 2001
1ED6
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-NIO (H4B FREE)
Descriptor:NITRIC OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Southan, G.J., Masters, B.S.S., Poulos, T.L.
Deposit date:2000-01-26
Release date:2001-01-31
Modification date:2011-07-13
Cite:Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
Biochemistry, 40, 2001
1FOI
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1400W(H4B-FREE)
Descriptor:NITRIC-OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Masters, B.S.S., Poulos, T.L.
Deposit date:2000-08-28
Release date:2001-07-20
Modification date:2011-07-13
Cite:Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
Biochemistry, 40, 2001
1FOJ
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 7-NITROINDAZOLE-2-CARBOXAMIDINE (H4B PRESENT)
Descriptor:NITRIC-OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Masters, B.S., Poulos, T.L.
Deposit date:2000-08-28
Release date:2001-11-16
Modification date:2011-07-13
Cite:Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism
Biochemistry, 40, 2001
1FOL
REDUCED BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG(H4B-FREE)
Descriptor:NITRIC-OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Masters, B.S., Poulos, T.L.
Deposit date:2000-08-28
Release date:2001-07-20
Modification date:2011-07-13
Cite:Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors
Biochemistry, 40, 2001
1FOO
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG AND NO(H4B-FREE)
Descriptor:NITRIC-OXIDE SYNTHASE (E.C.1.14.13.39)
Authors:Raman, C.S., Li, H., Martasek, P., Masters, B.S.S., Poulos, T.L.
Deposit date:2000-08-28
Release date:2001-07-20
Modification date:2011-07-13
Cite:Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
Biochemistry, 40, 2001
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