PDB keyword search results

1BIF
6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE BIFUNCTIONAL ENZYME COMPLEXED WITH ATP-G-S AND PHOSPHATE
Descriptor:6-PHOSPHOFRUCTO-2-KINASE/ FRUCTOSE-2,6-BISPHOSPHATASE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Hasemann, C.A., Deisenhofer, J.
Deposit date:1996-11-08
Release date:1997-11-12
Modification date:2012-02-15
Cite:The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies.
Structure, 4, 1996
1K6M
CRYSTAL STRUCTURE OF HUMAN LIVER 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE
Descriptor:6-phosphofructo-2-kinase (e.c.2.7.1.105)/fructose-2,6-biphosphatase 2-phosphotase (e.c.3.1.3.46)
Authors:Lee, Y.H., Li, Y., Uyeda, K., Hasemann, C.A.
Deposit date:2001-10-16
Release date:2002-12-11
Modification date:2012-03-07
Cite:Tissue-specific structure/function differentiation of the liver isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
J.Biol.Chem., 278, 2003
2AXN
CRYSTAL STRUCTURE OF THE HUMAN INDUCIBLE FORM 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE
Descriptor:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme) (iPFK-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Authors:Kim, S.G., Manes, N.P., El-Maghrabi, M.R., Lee, Y.H.
Deposit date:2005-09-05
Release date:2005-12-06
Modification date:2009-06-09
Cite:Crystal structure of the hypoxia-inducible form of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3): a possible new target for cancer therapy.
J.Biol.Chem., 281, 2006
2BIF
6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE H256A MUTANT WITH F6P IN PHOSPHATASE ACTIVE SITE
Descriptor:PROTEIN (6-PHOSPHOFRUCTO-2-KINASE/ FRUCTOSE-2,6-BISPHOSPHATASE) (2.7.1.105) MUTANT (W15F, W64F, H256A, W299F, W320F)
Authors:Yuen, M.H., Hasemann, C.A.
Deposit date:1998-10-26
Release date:1999-02-16
Modification date:2009-02-24
Cite:Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities.
J.Biol.Chem., 274, 1999
2DWO
PFKFB3 IN COMPLEX WITH ADP AND PEP
Descriptor:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (E.C.2.7.1.105/3.1.3.46)
Authors:Lee, Y.H.
Deposit date:2006-08-16
Release date:2007-07-03
Modification date:2008-05-06
Cite:A Direct Substrate-Substrate Interaction Found in the Kinase Domain of the Bifunctional Enzyme, 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase
J.Mol.Biol., 370, 2007
2DWP
A PSEUDO SUBSTRATE COMPLEX OF 6-PHOSPHOFRUCTO-2-KINASE OF PFKFB
Descriptor:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (E.C.2.7.1.105/3.1.3.46)
Authors:Lee, Y.H.
Deposit date:2006-08-16
Release date:2007-07-03
Modification date:2008-05-06
Cite:A Direct Substrate-Substrate Interaction Found in the Kinase Domain of the Bifunctional Enzyme, 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase
J.Mol.Biol., 370, 2007
2I1V
CRYSTAL STRUCTURE OF PFKFB3 IN COMPLEX WITH ADP AND FRUCTOSE-2,6-BISPHOSPHATE
Descriptor:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (E.C.2.7.1.105/3.1.3.46)
Authors:Kim, S.G., El-Maghrabi, M.R., Lee, Y.H.
Deposit date:2006-08-15
Release date:2007-07-03
Modification date:2008-05-06
Cite:A Direct Substrate-Substrate Interaction Found in the Kinase Domain of the Bifunctional Enzyme, 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase
J.Mol.Biol., 370, 2007
3BIF
6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE EMPTY 6-PF-2K ACTIVE SITE
Descriptor:6-PHOSPHOFRUCTO-2-KINASE (E.C.2.7.1.105)/FRUCTOSE-2,6-BISPHOSPHATASE
Authors:Yuen, M.H., Hasemann, C.A.
Deposit date:1999-05-05
Release date:1999-09-29
Modification date:2009-02-24
Cite:A switch in the kinase domain of rat testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
Biochemistry, 38, 1999
3QPU
PFKFB3 IN COMPLEX WITH PPI
Descriptor:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (E.C.2.7.1.105, 3.1.3.46)
Authors:Cavalier, M.C., Kim, S.G., Neau, D., Lee, Y.H.
Deposit date:2011-02-14
Release date:2012-02-08
Modification date:2012-03-21
Cite:Molecular basis of the fructose-2,6-bisphosphatase reaction of PFKFB3: Transition state and the C-terminal function.
Proteins, 80, 2012
3QPV
PFKFB3 TRAPPED IN A PHOSPHO-ENZYME INTERMEDIATE STATE
Descriptor:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (E.C.2.7.1.105, 3.1.3.46)
Authors:Cavalier, M.C., Kim, S.G., Neau, D., Lee, Y.H.
Deposit date:2011-02-14
Release date:2012-02-08
Modification date:2012-03-21
Cite:Molecular basis of the fructose-2,6-bisphosphatase reaction of PFKFB3: Transition state and the C-terminal function.
Proteins, 80, 2012
3QPW
PFKFB3 IN COMPLEX WITH ALUMINUM TETRAFLUORIDE
Descriptor:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (E.C.2.7.1.105, 3.1.3.46)
Authors:Cavalier, M.C., Kim, S.G., Neau, D., Lee, Y.H.
Deposit date:2011-02-14
Release date:2012-02-08
Modification date:2012-03-21
Cite:Molecular basis of the fructose-2,6-bisphosphatase reaction of PFKFB3: Transition state and the C-terminal function.
Proteins, 80, 2012
4MA4
S-GLUTATHIONYLATED PFKFB3
Descriptor:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (E.C.2.7.1.105, 3.1.3.46)
Authors:Lee, Y.-H., Seo, M.-S.
Deposit date:2013-08-15
Release date:2013-12-11
Modification date:2014-02-12
Cite:PFKFB3 Regulates Oxidative Stress Homeostasis via Its S-Glutathionylation in Cancer.
J.Mol.Biol., 426, 2014
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