PDB keyword search results

1BMQ
CRYSTAL STRUCTURE OF THE COMPLEX OF INTERLEUKIN-1BETA CONVERTING ENZYME (ICE) WITH A PEPTIDE BASED INHIBITOR, (3S )-N-METHANESULFONYL-3-({1-[N-(2-NAPHTOYL)-L-VALYL]-L-PROLYL }AMINO)-4-OXOBUTANAMIDE
Descriptor:INTERLEUKIN-1 BETA CONVERTASE
Authors:Okamoto, Y., Anan, H., Nakai, E., Morihira, K., Yonetoku, Y., Kurihara, H., Katayama, N., Sakashita, H., Terai, Y., Takeuchi, M., Shibanuma, T., Isomura, Y.
Deposit date:1998-07-24
Release date:1998-07-29
Modification date:2009-02-24
Cite:Peptide based interleukin-1 beta converting enzyme (ICE) inhibitors: synthesis, structure activity relationships and crystallographic study of the ICE-inhibitor complex.
Chem.Pharm.Bull., 47, 1999
1F9E
CASPASE-8 SPECIFICITY PROBED AT SUBSITE S4: CRYSTAL STRUCTURE OF THE CASPASE-8-Z-DEVD-CHO
Descriptor:CASPASE-8 (E.C.3.4.22.-)
Authors:Blanchard, H., Donepudi, M., Tschopp, M., Kodandapani, L., Wu, J.C., Grutter, M.G.
Deposit date:2000-07-10
Release date:2001-07-10
Modification date:2011-07-13
Cite:Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complex.
J.Mol.Biol., 302, 2000
1GFW
THE 2.8 ANGSTROM CRYSTAL STRUCTURE OF CASPASE-3 (APOPAIN OR CPP32)IN COMPLEX WITH AN ISATIN SULFONAMIDE INHIBITOR.
Descriptor:CASPASE-3 (APOPAIN OR CPP32)IN COMPLEX WITH AN ISATIN SULFONAMIDE INHIBITOR.
Authors:Concha, N.O., Janson, C.A.
Deposit date:2000-06-16
Release date:2000-06-23
Modification date:2009-02-24
Cite:Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality.
J.Biol.Chem., 275, 2000
1I3O
CRYSTAL STRUCTURE OF THE COMPLEX OF XIAP-BIR2 AND CASPASE 3
Descriptor:CASPASE 3 (E.C.3.4.22.-)/XIAP-BIR2 Complex
Authors:Riedl, S.J., Renatus, M., Schwarzenbacher, R., Zhou, Q., Sun, C., Fesik, S.W., Liddington, R.C., Salvesen, G.S.
Deposit date:2001-02-15
Release date:2001-03-21
Modification date:2009-02-24
Cite:Structural basis for the inhibition of caspase-3 by XIAP.
Cell(Cambridge,Mass.), 104, 2001
1I51
CRYSTAL STRUCTURE OF CASPASE-7 COMPLEXED WITH XIAP
Descriptor:CASPASE-7 SUBUNIT P20 (E.C.3.4.22.-)/CASPASE-7 SUBUNIT P11 (E.C.3.4.22.-)/XIAP
Authors:Chai, J., Shi, Y.
Deposit date:2001-02-23
Release date:2002-02-23
Modification date:2009-02-24
Cite:Structural basis of caspase-7 inhibition by XIAP.
Cell(Cambridge,Mass.), 104, 2001
1IBC
CRYSTAL STRUCTURE OF INHIBITED INTERLEUKIN-1BETA CONVERTING ENZYME
Descriptor:INTERLEUKIN-1BETA CONVERTING ENZYME, PEPTIDE ACE-TRP-GLU-HIS-ASP
Authors:Becker, J.W., Rotonda, J.
Deposit date:1997-02-12
Release date:1998-02-11
Modification date:2011-11-16
Cite:A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE).
Chem.Biol., 4, 1997
1ICE
STRUCTURE AND MECHANISM OF INTERLEUKIN-1BETA CONVERTING ENZYME
Descriptor:INTERLEUKIN 1-BETA CONVERTING ENZYME (ICE) (E.C.3.4.22.36)
Authors:Wilson, K.P., Griffith, J.P., Kim, E.E., Navia, M.A.
Deposit date:1994-09-29
Release date:1995-07-28
Modification date:2011-07-13
Cite:Structure and mechanism of interleukin-1 beta converting enzyme.
Nature, 370, 1994
1NME
STRUCTURE OF CASP-3 WITH TETHERED SALICYLATE
Descriptor:caspase-3 large and small subunits (E.C.3.4.22.-)
Authors:Erlanson, D.A., Lam, J., Wiesmann, C., Luong, T.N., Simmons, B., DeLano, W., Choong, I.C., Flanagan, M., Lee, D., O'Brian, T.
Deposit date:2003-01-09
Release date:2003-03-11
Modification date:2009-02-24
Cite:In situ assembly of enzyme inhibitors using extended tethering.
Nat.Biotechnol., 21, 2003
1PAU
CRYSTAL STRUCTURE OF THE COMPLEX OF APOPAIN WITH THE TETRAPEPTIDE ALDEHYDE INHIBITOR AC-DEVD-CHO
Descriptor:APOPAIN, ACE-ASP-GLU-VAL-ASP-CHO
Authors:Rotonda, J., Becker, J.W.
Deposit date:1996-06-06
Release date:1997-07-07
Modification date:2011-07-13
Cite:The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis.
Nat.Struct.Biol., 3, 1996
1PYO
CRYSTAL STRUCTURE OF HUMAN CASPASE-2 IN COMPLEX WITH ACETYL-LEU-ASP-GLU-SER-ASP-CHO
Descriptor:Caspase-2, subunit p18 (E.C.3.4.22.-)/Caspase-2, subunit p18 (E.C.3.4.22.-)/Ace-LDESD peptide
Authors:Schweizer, A., Briand, C., Grutter, M.G.
Deposit date:2003-07-09
Release date:2003-08-26
Modification date:2013-07-03
Cite:Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway.
J.Biol.Chem., 278, 2003
1QDU
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-8 WITH THE TRIPEPTIDE KETONE INHIBITOR ZEVD-DCBMK
Descriptor:CASPASE-8 ALPHA-CHAIN/CASPASE-8 BETA-CHAIN/Z-EVD-DCBMK
Authors:Blanchard, H., Grutter, M.G.
Deposit date:1999-07-10
Release date:2000-07-10
Modification date:2011-07-13
Cite:The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis.
Structure Fold.Des., 7, 1999
1QTN
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-8 WITH THE TETRAPEPTIDE INHIBITOR ACE-IETD-ALDEHYDE
Descriptor:CASPASE-8 (E.C.3.4.22.-)
Authors:Watt, W., Watenpaugh, K.D.
Deposit date:1999-06-28
Release date:2000-09-20
Modification date:2012-04-04
Cite:The atomic-resolution structure of human caspase-8, a key activator of apoptosis.
Structure Fold.Des., 7, 1999
1RE1
CRYSTAL STRUCTURE OF CASPASE-3 WITH A NICOTINIC ACID ALDEHYDE INHIBITOR
Descriptor:Caspase-3 (E.C.3.4.22.-)
Authors:Becker, J.W., Rotonda, J., Soisson, S.M.
Deposit date:2003-11-06
Release date:2004-05-11
Modification date:2011-07-13
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis
J.Med.Chem., 47, 2004
1RHJ
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A PRYAZINONE INHIBITOR
Descriptor:Apopain precursor (E.C.3.4.22.-)
Authors:Becker, J.W., Rotonda, J., Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Modification date:2009-02-24
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
1RHK
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A PHENYL-PROPYL-KETONE INHIBITOR
Descriptor:Apopain (E.C.3.4.22.-), acetyl-asp-glu-val-asp-phenyl propyl ketone
Authors:Becker, J.W., Rotonda, J., Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Modification date:2011-07-27
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
1RHM
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A NICOTINIC ACID ALDEHYDE INHIBITOR
Descriptor:Apopain precursor (E.C.3.4.22.-)
Authors:Becker, J.W., Rotonda, J., Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Modification date:2009-02-24
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
1RHQ
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A BROMOMETHOXYPHENYL INHIBITOR
Descriptor:Apopain (E.C.3.4.22.-)
Authors:Becker, J.W., Rotonda, J., Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Modification date:2014-01-22
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
1RHR
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A CINNAMIC ACID METHYL ESTER INHIBITOR
Descriptor:Apopain (E.C.3.4.22.-)
Authors:Becker, J.W., Rotonda, J., Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Modification date:2011-07-13
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
1RHU
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A 5,6,7 TRICYCLIC PEPTIDOMIMETIC INHIBITOR
Descriptor:Apopain (E.C.3.4.22.-)
Authors:Becker, J.W., Rotonda, J., Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Modification date:2011-07-13
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
1RWK
CRYSTAL STRUCTURE OF HUMAN CASPASE-1 IN COMPLEX WITH 3-(2-MERCAPTO-ACETYLAMINO)-4-OXO-PENTANOIC ACID
Descriptor:Interleukin-1 beta convertase (E.C.3.4.22.36)
Authors:Romanowski, M.J., Lam, J.W., Fahr, B.T., O'Brien, T.
Deposit date:2003-12-16
Release date:2004-12-28
Modification date:2011-07-13
Cite:Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWM
CRYSTAL STRUCTURE OF HUMAN CASPASE-1 IN COMPLEX WITH 4-OXO-3-[2-(5-{[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-METHYL}-THIOPHEN-2-YL)-ACETYLAMINO]-PENTANOIC ACID
Descriptor:Interleukin-1 beta convertase (E.C.3.4.22.36)
Authors:Romanowski, M.J., Waal, N.D., Fahr, B.T., O'Brien, T.
Deposit date:2003-12-16
Release date:2004-12-28
Modification date:2011-07-13
Cite:Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWN
CRYSTAL STRUCTURE OF HUMAN CASPASE-1 IN COMPLEX WITH 3-{2-ETHYL-6-[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-HEXANOYLAMINO}-4-OXO-BUTYRIC ACID
Descriptor:Interleukin-1 beta convertase (E.C.3.4.22.36)
Authors:Romanowski, M.J., Fahr, B.T., O'Brien, T.
Deposit date:2003-12-16
Release date:2004-12-28
Modification date:2011-07-13
Cite:Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWO
CRYSTAL STRUCTURE OF HUMAN CASPASE-1 IN COMPLEX WITH 4-OXO-3-{6-[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-PENTANOIC ACID
Descriptor:Interleukin-1 beta convertase (E.C.3.4.22.36)
Authors:Romanowski, M.J., Waal, N.D., Fahr, B.T., O'Brien, T.
Deposit date:2003-12-16
Release date:2004-12-28
Modification date:2011-07-13
Cite:Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWP
CRYSTAL STRUCTURE OF HUMAN CASPASE-1 IN COMPLEX WITH 3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRIC ACID
Descriptor:Interleukin-1 beta convertase (E.C.3.4.22.36)
Authors:Romanowski, M.J., Fahr, B.T., O'Brien, T.
Deposit date:2003-12-16
Release date:2004-12-28
Modification date:2011-07-13
Cite:Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWV
CRYSTAL STRUCTURE OF HUMAN CASPASE-1 IN COMPLEX WITH 5-[5-(1-CARBOXYMETHYL-2-OXO-PROPYLCARBAMOYL)-5-PHENYL-PENTYLSULFAMOYL]-2-HYDROXY-BENZOIC ACID
Descriptor:Interleukin-1 beta convertase (E.C.3.4.22.36)
Authors:Romanowski, M.J., Burdett, M.T., Fahr, B.T., O'Brien, T.
Deposit date:2003-12-17
Release date:2004-12-28
Modification date:2011-07-13
Cite:Novel Caspase-1 Inhibitors Discovered Using Tethering(SM) with Extenders
TO BE PUBLISHED
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