PDB keyword search results

1DMW
CRYSTAL STRUCTURE OF DOUBLE TRUNCATED HUMAN PHENYLALANINE HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN
Descriptor:PHENYLALANINE HYDROXYLASE (E.C.1.14.16.1)
Authors:Erlandsen, H., Stevens, R.C., Flatmark, T.
Deposit date:1999-12-15
Release date:2000-03-24
Modification date:2009-02-24
Cite:Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase.
Biochemistry, 39, 2000
1J8T
CATALYTIC DOMAIN OF HUMAN PHENYLALANINE HYDROXYLASE FE(II)
Descriptor:PHENYLALANINE-4-HYDROXYLASE (E.C.1.14.16.1)
Authors:Andersen, O.A., Flatmark, T., Hough, E.
Deposit date:2001-05-22
Release date:2002-05-22
Modification date:2009-02-24
Cite:High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin.
J.Mol.Biol., 314, 2001
1J8U
CATALYTIC DOMAIN OF HUMAN PHENYLALANINE HYDROXYLASE FE(II) IN COMPLEX WITH TETRAHYDROBIOPTERIN
Descriptor:PHENYLALANINE-4-HYDROXYLASE (E.C.1.14.16.1)
Authors:Andersen, O.A., Flatmark, T., Hough, E.
Deposit date:2001-05-22
Release date:2002-05-22
Modification date:2009-02-24
Cite:High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin.
J.Mol.Biol., 314, 2001
1KW0
CATALYTIC DOMAIN OF HUMAN PHENYLALANINE HYDROXYLASE (FE(II)) IN COMPLEX WITH TETRAHYDROBIOPTERIN AND THIENYLALANINE
Descriptor:Phenylalanine-4-hydroxylase (E.C.1.14.16.1)
Authors:Andersen, O.A., Flatmark, T., Hough, E.
Deposit date:2002-01-28
Release date:2003-01-28
Modification date:2009-02-24
Cite:Crystal Structure of the Ternary Complex of the Catalytic Domain of Human Phenylalanine Hydroxylase with Tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its Implications for the Mechanism of Catalysis and Substrate Activation
J.Mol.Biol., 320, 2002
1LRM
CRYSTAL STRUCTURE OF BINARY COMPLEX OF THE CATALYTIC DOMAIN OF HUMAN PHENYLALANINE HYDROXYLASE WITH DIHYDROBIOPTERIN (BH2)
Descriptor:Phenylalanine-4-hydroxylase
Authors:Andersen, O.A.
Deposit date:2002-05-15
Release date:2002-06-12
Modification date:2009-02-24
Cite:

1LTU
CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM, APO (NO IRON BOUND) STRUCTURE
Descriptor:PHENYLALANINE-4-HYDROXYLASE (E.C.1.14.16.1)
Authors:Erlandsen, H., Kim, J.Y., Patch, M.G., Han, A., Volner, A., Abu-Omar, M.M., Stevens, R.C.
Deposit date:2002-05-20
Release date:2002-07-17
Modification date:2009-02-24
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1LTV
CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE WITH BOUND OXIDIZED FE(III)
Descriptor:PHENYLALANINE-4-HYDROXYLASE (E.C.1.14.16.1)
Authors:Erlandsen, H., Kim, J.Y., Patch, M.G., Han, A., Volner, A., Abu-Omar, M.M., Stevens, R.C.
Deposit date:2002-05-20
Release date:2002-07-17
Modification date:2009-02-24
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1LTZ
CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE HAS BOUND IRON (III) AND OXIDIZED COFACTOR 7,8-DIHYDROBIOPTERIN
Descriptor:PHENYLALANINE-4-HYDROXYLASE (E.C.1.14.16.1)
Authors:Erlandsen, H., Kim, J.Y., Patch, M.G., Han, A., Volner, A., Abu-Omar, M.M., Stevens, R.C.
Deposit date:2002-05-21
Release date:2002-07-17
Modification date:2009-02-24
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1MLW
CRYSTAL STRUCTURE OF HUMAN TRYPTOPHAN HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN COFACTOR AND FE(III)
Descriptor:Tryptophan 5-monooxygenase (E.C.1.14.16.4)
Authors:Wang, L., Erlandsen, H., Haavik, J., Knappskog, P.M., Stevens, R.C.
Deposit date:2002-08-31
Release date:2002-12-18
Modification date:2009-02-24
Cite:Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin
Biochemistry, 41, 2002
1MMK
CRYSTAL STRUCTURE OF TERNARY COMPLEX OF THE CATALYTIC DOMAIN OF HUMAN PHENYLALANINE HYDROXYLASE ((FEII)) COMPLEXED WITH TETRAHYDROBIOPTERIN AND THIENYLALANINE
Descriptor:Phenylalanine-4-hydroxylase(E.C.1.14.16.1)
Authors:Andersen, O.A., Flatmark, T., Hough, E.
Deposit date:2002-09-04
Release date:2003-09-04
Modification date:2009-02-24
Cite:2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding
J.Mol.Biol., 333, 2003
1MMT
CRYSTAL STRUCTURE OF TERNARY COMPLEX OF THE CATALYTIC DOMAIN OF HUMAN PHENYLALANINE HYDROXYLASE (FE(II)) COMPLEXED WITH TETRAHYDROBIOPTERIN AND NORLEUCINE
Descriptor:Phenylalanine-4-hydroxylase(E.C.1.14.16.1)
Authors:Andersen, O.A., Flatmark, T., Hough, E.
Deposit date:2002-09-04
Release date:2003-09-04
Modification date:2009-02-24
Cite:2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding
J.Mol.Biol., 333, 2003
1PAH
HUMAN PHENYLALANINE HYDROXYLASE DIMER, RESIDUES 117-424
Descriptor:PHENYLALANINE HYDROXYLASE
Authors:Stevens, R.C., Erlandsen, H.
Deposit date:1997-10-25
Release date:1999-01-13
Modification date:2009-02-24
Cite:Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria.
Nat.Struct.Biol., 4, 1997
1TDW
CRYSTAL STRUCTURE OF DOUBLE TRUNCATED HUMAN PHENYLALANINE HYDROXYLASE BH4-RESPONSIVE PKU MUTANT A313T.
Descriptor:Phenylalanine-4-hydroxylase (E.C.1.14.16.1)
Authors:Erlandsen, H., Pey, A.L., Gamez, A., Perez, B., Desviat, L.R., Aguado, C., Koch, R., Surendran, S., Tyring, S., Matalon, R., Scriver, C.R., Ugarte, M., Martinez, A., Stevens, R.C.
Deposit date:2004-05-24
Release date:2004-11-30
Modification date:2009-02-24
Cite:Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1TG2
CRYSTAL STRUCTURE OF PHENYLALANINE HYDROXYLASE A313T MUTANT WITH 7,8-DIHYDROBIOPTERIN BOUND
Descriptor:Phenylalanine-4-hydroxylase (E.C.1.14.16.1)
Authors:Erlandsen, H., Pey, A.L., Gamez, A., Perez, B., Desviat, L.R., Aguado, C., Koch, R., Surendran, S., Tyring, S., Matalon, R., Scriver, C.R., Ugarte, M., Martinez, A., Stevens, R.C.
Deposit date:2004-05-28
Release date:2004-11-30
Modification date:2009-02-24
Cite:Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1TOH
TYROSINE HYDROXYLASE CATALYTIC AND TETRAMERIZATION DOMAINS FROM RAT
Descriptor:TYROSINE HYDROXYLASE
Authors:Goodwill, K.E., Sabatier, C., Stevens, R.C.
Deposit date:1997-06-04
Release date:1998-06-03
Modification date:2011-07-13
Cite:Crystal structure of tyrosine hydroxylase at 2.3 A and its implications for inherited neurodegenerative diseases.
Nat.Struct.Biol., 4, 1997
2PAH
TETRAMERIC HUMAN PHENYLALANINE HYDROXYLASE
Descriptor:PROTEIN (PHENYLALANINE HYDROXYLASE) (1.14.16.1)
Authors:Stevens, R.C., Fusetti, F., Erlandsen, H.
Deposit date:1998-05-26
Release date:1999-10-06
Modification date:2011-07-13
Cite:Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria.
J.Biol.Chem., 273, 1998
2TOH
TYROSINE HYDROXYLASE CATALYTIC AND TETRAMERIZATION DOMAINS FROM RAT
Descriptor:TYROSINE 3-MONOOXYGENASE, 7,8-DIHYDROBIOPTERIN
Authors:Goodwill, K.E., Sabatier, C., Stevens, R.C.
Deposit date:1998-08-26
Release date:1999-08-26
Modification date:2011-07-13
Cite:Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 A resolution: self-hydroxylation of Phe300 and the pterin-binding site.
Biochemistry, 37, 1998
2V27
STRUCTURE OF THE COLD ACTIVE PHENYLALANINE HYDROXYLASE FROM COLWELLIA PSYCHRERYTHRAEA 34H
Descriptor:PHENYLALANINE HYDROXYLASE (E.C.1.14.16.1)
Authors:Leiros, H.-K.S., Pey, A.L., Innselset, M., Moe, E., Leiros, I., Steen, I.H., Martinez, A.
Deposit date:2007-06-03
Release date:2007-06-19
Modification date:2009-02-24
Cite:Structure of Phenylalanine Hydroxylase from Colwellia Psychrerythraea 34H, a Monomeric Cold Active Enzyme with Local Flexibility Around the Active Site and High Overall Stability.
J.Biol.Chem., 282, 2007
2V28
APO STRUCTURE OF THE COLD ACTIVE PHENYLALANINE HYDROXYLASE FROM COLWELLIA PSYCHRERYTHRAEA 34H
Descriptor:PHENYLALANINE-4-HYDROXYLASE (E.C.1.14.16.1)
Authors:Leiros, H.-K.S., Pey, A.L., Innselset, M., Moe, E., Leiros, I., Steen, I.H., Martinez, A.
Deposit date:2007-06-04
Release date:2007-06-19
Modification date:2009-02-24
Cite:Structure of Phenylalanine Hydroxylase from Colwellia Psychrerythraea 34H, a Monomeric Cold Active Enzyme with Local Flexibility Around the Active Site and High Overall Stability.
J.Biol.Chem., 282, 2007
2XSN
CRYSTAL STRUCTURE OF HUMAN TYROSINE HYDROXYLASE CATALYTIC DOMAIN
Descriptor:TYROSINE 3-MONOOXYGENASE (E.C.1.14.16.2)
Authors:Muniz, J.R.C., Cooper, C.D.O., Yue, W.W., Krysztofinska, E., Von Delft, F., Knapp, S., Gileadi, O., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Kavanagh, K.L., Oppermann, U.
Deposit date:2010-10-29
Release date:2010-11-17
Modification date:2012-12-05
Cite:Crystal Structure of Human Tyrosine Hydroxylase Catalytic Domain
To be Published
3E2T
THE CATALYTIC DOMAIN OF CHICKEN TRYPTOPHAN HYDROXYLASE 1 WITH BOUND TRYPTOPHAN
Descriptor:Tryptophan 5-hydroxylase 1 (E.C.1.14.16.4)
Authors:Windahl, M.S., Petersen, C.R., Christensen, H.E.C., Harris, P.
Deposit date:2008-08-06
Release date:2008-11-04
Modification date:2009-02-24
Cite:Crystal structure of tryptophan hydroxylase with bound amino acid substrate
Biochemistry, 47, 2008
3HF6
CRYSTAL STRUCTURE OF HUMAN TRYPTOPHAN HYDROXYLASE TYPE 1 WITH BOUND LP-521834 AND FE
Descriptor:Tryptophan 5-hydroxylase 1 (E.C.1.14.16.4)
Authors:Tari, L.W., Swanson, R.V., Hunter, M.J.
Deposit date:2009-05-11
Release date:2009-11-24
Modification date:2010-04-21
Cite:Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis
Curr Chem Genomics, 4, 2010
3HF8
CRYSTAL STRUCTURE OF HUMAN TRYOPTOPHAN HYDROXYLASE TYPE 1 WITH BOUND LP-533401 AND FE
Descriptor:Tryptophan 5-hydroxylase 1 (E.C.1.14.16.4)
Authors:Tari, L.W., Swanson, R.V., Hunter, M.J.
Deposit date:2009-05-11
Release date:2010-04-21
Modification date:2012-03-28
Cite:Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis.
Curr Chem Genomics, 4, 2010
3HFB
CRYSTAL STRUCTURE OF HUMAN TRYOPTOPHAN HYDROXYLASE TYPE 1 WITH LP-534193
Descriptor:Tryptophan 5-hydroxylase 1 (E.C.1.14.16.4)
Authors:Tari, L.W., Swanson, R.V., Hunter, M.J.
Deposit date:2009-05-11
Release date:2010-04-21
Modification date:2012-03-28
Cite:Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis.
Curr Chem Genomics, 4, 2010
3PAH
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND ADRENALINE INHIBITOR
Descriptor:PHENYLALANINE HYDROXYLASE, ADR L-EPINEPHRINE
Authors:Erlandsen, H., Flatmark, T., Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Modification date:2013-03-20
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
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