PDB keyword search results

3JQA
CRYSTAL STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND INHIBITOR 2-AMINO-1,9-DIHYDRO-6H-PURINE-6-THIONE (DX4)
Descriptor:Pteridine reductase 1 (E.C.1.5.1.33)
Authors:Tulloch, L.B., Hunter, W.N.
Deposit date:2009-09-06
Release date:2009-12-08
Modification date:2011-07-13
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
1E3W
RAT BRAIN 3-HYDROXYACYL-COA DEHYDROGENASE BINARY COMPLEX WITH NADH AND 3-KETO BUTYRATE
Descriptor:SHORT CHAIN 3-HYDROXYACYL-COA DEHYDROGENASE (E.C.1.1.1.35)
Authors:Powell, A.J., Read, J.A., Brady, R.L.
Deposit date:2000-06-26
Release date:2001-05-25
Modification date:2009-02-24
Cite:Recognition of Structurally Diverse Substrates by Type II 3-Hydroxyacyl-Coa Dehydrogenase (Hadh II) Amyloid-Beta Binding Alcohol Dehydrogenase (Abad)
J.Mol.Biol., 303, 2000
2WD7
PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH NADP AND DDD00066750
Descriptor:PTERIDINE REDUCTASE (E.C.1.5.1.33)
Authors:Robinson, D.A., Wyatt, P.G., Spinks, D., Brenk, R.
Deposit date:2009-03-20
Release date:2009-06-30
Modification date:2012-10-10
Cite:One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening.
J.Med.Chem., 52, 2009
2YHI
TRYPANOSOMA BRUCEI PTR1 IN COMPLEX WITH INHIBITOR WH16
Descriptor:PTERIDINE REDUCTASE, PUTATIVE (E.C.1.5.1.33)
Authors:Nerini, E., Dawson, A., Hunter, W.N., Costi, M.P.
Deposit date:2011-05-03
Release date:2012-05-23
Cite:Structural Studies of Thiadiazole Derivatives that Inhibit Trypanosoma Brucei Growth.
To be Published
3BMC
STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND SUBSTRATE (FOLATE)
Descriptor:Pteridine reductase
Authors:Tulloch, L.B., Hunter, W.N.
Deposit date:2007-12-13
Release date:2008-12-16
Modification date:2011-07-13
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
3BMN
STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND INHIBITOR (COMPOUND AX3)
Descriptor:Pteridine reductase
Authors:Martini, V.P., Iulek, J., Tulloch, L.B., Hunter, W.N.
Deposit date:2007-12-13
Release date:2008-12-16
Modification date:2011-07-13
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
3BMO
STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND INHIBITOR (COMPOUND AX4)
Descriptor:Pteridine reductase
Authors:Martini, V.P., Iulek, J., Hunter, W.N., Tulloch, L.B.
Deposit date:2007-12-13
Release date:2008-12-16
Modification date:2011-07-13
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
3BMQ
STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND INHIBITOR (COMPOUND AX5)
Descriptor:Pteridine reductase
Authors:Martini, V.P., Iulek, J., Hunter, W.N.
Deposit date:2007-12-13
Release date:2008-12-16
Modification date:2011-07-13
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
3D3W
STRUCTURE OF L-XYLULOSE REDUCTASE WITH BOUND COENZYME, PHOSPHATE AND HYDROXIDE.
Descriptor:L-xylulose reductase (E.C.1.1.1.10)
Authors:Zhao, H.-T., El-Kabbani, O.
Deposit date:2008-05-12
Release date:2009-04-21
Modification date:2009-07-28
Cite:Structure/function analysis of a critical disulfide bond in the active site of L-xylulose reductase.
Cell.Mol.Life Sci., 66, 2009
3JQ7
CRYSTAL STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND INHIBITOR 6-PHENYLPTERIDINE-2,4,7-TRIAMINE (DX2)
Descriptor:Pteridine reductase 1 (E.C.1.5.1.33)
Authors:Tulloch, L.B., Hunter, W.N.
Deposit date:2009-09-06
Release date:2009-12-08
Modification date:2011-07-13
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
3JQ8
CRYSTAL STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND INHIBITOR 6,7,7-TRIMETHYL-7,8-DIHYDROPTERIDINE-2,4-DIAMINE (DX3)
Descriptor:Pteridine reductase 1 (E.C.1.5.1.33)
Authors:Tulloch, L.B., Hunter, W.N.
Deposit date:2009-09-06
Release date:2009-12-08
Modification date:2011-07-13
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
3JQ9
CRYSTAL STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND INHIBITOR 2-AMINO-6-(1,3-BENZODIOXOL-5-YL)-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE (AX1)
Descriptor:Pteridine reductase 1 (E.C.1.5.1.33)
Authors:Tulloch, L.B., Hunter, W.N.
Deposit date:2009-09-06
Release date:2009-12-08
Modification date:2010-01-19
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
3JQB
CRYSTAL STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND INHIBITOR 2-AMINO-5-(2-PHENYLETHYL)-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE (DX6)
Descriptor:Pteridine reductase 1 (E.C.1.5.1.33)
Authors:Tulloch, L.B., Hunter, W.N.
Deposit date:2009-09-06
Release date:2009-12-08
Modification date:2010-01-19
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
3JQF
CRYSTAL STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND INHIBITOR 1,3,5-TRIAZINE-2,4,6-TRIAMINE (AX2)
Descriptor:Pteridine reductase 1 (E.C.1.5.1.33)
Authors:Tulloch, L.B., Hunter, W.N.
Deposit date:2009-09-06
Release date:2009-12-08
Modification date:2012-12-26
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
3JQG
CRYSTAL STRUCTURE OF PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN TERNARY COMPLEX WITH COFACTOR (NADP+) AND INHIBITOR 6-[(4-METHOXYBENZYL)SULFANYL]PYRIMIDINE-2,4-DIAMINE (AX6)
Descriptor:Pteridine reductase 1 (E.C.1.5.1.33)
Authors:Tulloch, L.B., Hunter, W.N.
Deposit date:2009-09-06
Release date:2009-12-08
Modification date:2011-07-13
Cite:Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
1A27
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 C-TERMINAL DELETION MUTANT COMPLEXED WITH ESTRADIOL AND NADP+
Descriptor:17-BETA-HYDROXYSTEROID-DEHYDROGENASE, ESTRADIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Mazza, C., Breton, R., Housset, D., Fontecilla-Camps, J.-C.
Deposit date:1998-01-16
Release date:1998-05-27
Modification date:2011-07-13
Cite:Human Type I 17Beta-Hydroxysteroid Dehydrogenase: Site Directed Mutagenesis and X-Ray Crystallography Structure-Function Analysis
Thesis, Universite Joseph Fourier, 1997
1A4U
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS
Descriptor:ALCOHOL DEHYDROGENASE
Authors:Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Deposit date:1998-02-05
Release date:1999-02-16
Modification date:2009-02-24
Cite:The refined crystal structure of Drosophila lebanonensis alcohol dehydrogenase at 1.9 A resolution.
J.Mol.Biol., 282, 1998
1AE1
TROPINONE REDUCTASE-I COMPLEX WITH NADP
Descriptor:TROPINONE REDUCTASE-I, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Nakajima, K., Yamashita, A., Akama, H., Nakatsu, T., Kato, H., Hashimoto, T., Oda, J., Yamada, Y.
Deposit date:1997-10-23
Release date:1998-11-18
Modification date:2009-02-24
Cite:Crystal structures of two tropinone reductases: different reaction stereospecificities in the same protein fold.
Proc.Natl.Acad.Sci.USA, 95, 1998
1AHH
7 ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEXED WITH NAD+
Descriptor:7 ALPHA-HYDROXYSTEROID DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Tanaka, N., Nonaka, T., Mitsui, Y.
Deposit date:1995-08-25
Release date:1996-10-14
Modification date:2011-07-13
Cite:Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli.
Biochemistry, 35, 1996
1AHI
7 ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEXED WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID
Descriptor:7 ALPHA-HYDROXYSTEROID DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Tanaka, N., Nonaka, T., Mitsui, Y.
Deposit date:1995-08-25
Release date:1996-10-14
Modification date:2013-10-30
Cite:Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli.
Biochemistry, 35, 1996
1B14
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS BINARY COMPLEX WITH NAD+
Descriptor:ALCOHOL DEHYDROGENASE (E.C.1.1.1.1)
Authors:Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Deposit date:1998-11-25
Release date:1999-11-26
Modification date:2011-07-13
Cite:The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.
J.Mol.Biol., 289, 1999
1B15
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS TERNARY COMPLEX WITH NAD-ACETONE
Descriptor:ALCOHOL DEHYDROGENASE (E.C.1.1.1.1)
Authors:Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Deposit date:1998-11-25
Release date:1999-11-26
Modification date:2009-02-24
Cite:The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.
J.Mol.Biol., 289, 1999
1B16
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS TERNARY COMPLEX WITH NAD-3-PENTANONE
Descriptor:PROTEIN (ALCOHOL DEHYDROGENASE) (1.1.1.1)
Authors:Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Deposit date:1998-11-25
Release date:1999-11-29
Modification date:2011-07-13
Cite:The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.
J.Mol.Biol., 289, 1999
1B2L
ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS: TERNARY COMPLEX WITH NAD-CYCLOHEXANONE
Descriptor:ALCOHOL DEHYDROGENASE (E.C.1.1.1.1)
Authors:Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Deposit date:1998-11-26
Release date:1999-11-26
Modification date:2011-07-13
Cite:The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.
J.Mol.Biol., 289, 1999
1BDB
CIS-BIPHENYL-2,3-DIHYDRODIOL-2,3-DEHYDROGENASE FROM PSEUDOMONAS SP. LB400
Descriptor:CIS-BIPHENYL-2,3-DIHYDRODIOL-2,3-DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Huelsmeyer, M., Hecht, H.-J., Niefind, K., Hofer, B., Timmis, K.N., Schomburg, D.
Deposit date:1997-05-10
Release date:1997-11-12
Modification date:2011-07-13
Cite:Crystal structure of cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase from a PCB degrader at 2.0 A resolution.
Protein Sci., 7, 1998
Loading...
Loading