PDB keyword search results

1DKF
CRYSTAL STRUCTURE OF A HETERODIMERIC COMPLEX OF RAR AND RXR LIGAND-BINDING DOMAINS
Descriptor:RETINOID X RECEPTOR-ALPHA
Authors:Bourguet, W., Vivat, V., Wurtz, J.M., Chambon, P., Gronemeyer, H., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:1999-12-07
Release date:2000-04-19
Modification date:2009-02-24
Cite:Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains.
Mol.Cell, 5, 2000
1FM6
THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES.
Descriptor:RETINOIC ACID RECEPTOR RXR-ALPHA
Authors:Gampe Jr., R.T., Montana, V.G., Lambert, M.H., Miller, A.B., Bledsoe, R.K., Milburn, M.V., Kliewer, S.A., Willson, T.M., Xu, H.E.
Deposit date:2000-08-16
Release date:2001-02-16
Modification date:2012-12-26
Cite:Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors.
Mol.Cell, 5, 2000
1FM9
THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES.
Descriptor:RETINOIC ACID RECEPTOR RXR-ALPHA
Authors:Gampe Jr., R.T., Montana, V.G., Lambert, M.H., Miller, A.B., Bledsoe, R.K., Milburn, M.V., Kliewer, S.A., Willson, T.M., Xu, H.E.
Deposit date:2000-08-16
Release date:2001-02-16
Modification date:2012-12-26
Cite:Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors.
Mol.Cell, 5, 2000
1K74
THE 2.3 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN PPARGAMMA AND RXRALPHA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH GW409544 AND 9-CIS RETINOIC ACID AND CO-ACTIVATOR PEPTIDES.
Descriptor:Retinoic acid receptor RXR-alpha/Peroxisome proliferator activated receptor gamma/steroid receptor coactivator
Authors:Xu, H.E., Lambert, M.H., Montana, V.G., Moore, L.B., Collins, J.L., Oplinger, J.A., Kliewer, S.A., Gampe Jr., R.T., McKee, D.D., Moore, J.T., Willson, T.M.
Deposit date:2001-10-18
Release date:2001-12-05
Modification date:2012-12-26
Cite:Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors.
Proc.Natl.Acad.Sci.USA, 98, 2001
1OVL
CRYSTAL STRUCTURE OF NURR1 LBD
Descriptor:Orphan nuclear receptor NURR1
Authors:Wang, Z., Liu, J., Walker, N.
Deposit date:2003-03-26
Release date:2003-06-03
Modification date:2009-02-24
Cite:Structure and Function of Nurr1 identifies a Class of Ligand-Independent Nuclear Receptors
Nature, 423, 2003
1R1K
CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAINS OF THE HETERODIMER ECR/USP BOUND TO PONASTERONE A
Descriptor:Ecdysone receptor, ULTRASPIRACLE PROTEIN , 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE
Authors:Billas, I.M.L., Iwema, T., Garnier, J.-M., Mitschler, A., Rochel, N., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2003-09-24
Release date:2003-11-18
Modification date:2009-02-24
Cite:Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.
Nature, 426, 2003
1R20
CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAINS OF THE HETERODIMER ECR/USP BOUND TO THE SYNTHETIC AGONIST BYI06830
Descriptor:ULTRASPIRACLE PROTEIN/ECDYSONE RECEPTOR
Authors:Billas, I.M.L., Iwema, T., Garnier, J.M., Mitschler, A., Rochel, N., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2003-09-25
Release date:2003-11-18
Modification date:2009-02-24
Cite:Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.
Nature, 426, 2003
1RDT
CRYSTAL STRUCTURE OF A NEW REXINOID BOUND TO THE RXRALPHA LIGAND BINDING DOAMIN IN THE RXRALPHA/PPARGAMMA HETERODIMER
Descriptor:Retinoic acid receptor RXR-alpha, LxxLL motif coactivator, Peroxisome proliferator activated receptor gamma
Authors:Haffner, C.D., Lenhard, J.M., Miller, A.B., McDougald, D.L., Dwornik, K., Ittoop, O.R., Gampe Jr., R.T., Xu, H.E., Blanchard, S., Montana, V.G.
Deposit date:2003-11-06
Release date:2004-11-09
Modification date:2009-02-24
Cite:Structure-based design of potent retinoid X receptor alpha agonists.
J.Med.Chem., 47, 2004
1UHL
CRYSTAL STRUCTURE OF THE LXRALFA-RXRBETA LBD HETERODIMER
Descriptor:Retinoic acid receptor RXR-beta/Oxysterols receptor LXR-alpha
Authors:Svensson, S., Ostberg, T., Jacobsson, M., Norstrom, C., Stefansson, K., Hallen, D., Johansson, I.C., Zachrisson, K., Ogg, D., Jendeberg, L.
Deposit date:2003-07-03
Release date:2004-06-01
Modification date:2009-02-24
Cite:Crystal structure of the heterodimeric complex of LXRalpha and RXRbeta ligand-binding domains in a fully agonistic conformation
Embo J., 22, 2003
1XDK
CRYSTAL STRUCTURE OF THE RARBETA/RXRALPHA LIGAND BINDING DOMAIN HETERODIMER IN COMPLEX WITH 9-CIS RETINOIC ACID AND A FRAGMENT OF THE TRAP220 COACTIVATOR
Descriptor:Retinoic acid receptor RXR-alpha, Retinoic acid receptor, beta, peroxisome proliferator-activated receptor binding protein
Authors:Pogenberg, V., Guichou, J.F., Vivat-Hannah, V., Kammerer, S., Perez, E., Germain, P., De Lera, A.R., Gronemeyer, H., Royer, C.A., Bourguet, W.
Deposit date:2004-09-07
Release date:2004-11-09
Modification date:2009-02-24
Cite:CHARACTERIZATION OF THE INTERACTION BETWEEN RAR/RXR HETERODIMERS AND TRANSCRIPTIONAL COACTIVATORS THROUGH STRUCTURAL AND FLUORESCENCE ANISOTROPY STUDIES
J.Biol.Chem., 280, 2005
1XLS
CRYSTAL STRUCTURE OF THE MOUSE CAR/RXR LBD HETERODIMER BOUND TO TCPOBOP AND 9CRA AND A TIF2 PEPTIDE CONTAING THE THIRD LXXLL MOTIFS
Descriptor:Retinoic acid receptor RXR-alpha, Orphan nuclear receptor NR1I3, Nuclear receptor coactivator 2
Authors:Suino, K., peng, L., Reynolds, R., Li, Y., Cha, J.-Y., Repa, J.J., Kliewer, S.A., Xu, H.E.
Deposit date:2004-09-30
Release date:2004-12-28
Modification date:2009-02-24
Cite:The nuclear xenobiotic receptor CAR: structural determinants of constitutive activation and heterodimerization.
Mol.Cell, 16, 2004
1XV9
CRYSTAL STRUCTURE OF CAR/RXR HETERODIMER BOUND WITH SRC1 PEPTIDE, FATTY ACID, AND 5B-PREGNANE-3,20-DIONE.
Descriptor:Retinoic acid receptor RXR-alpha, Orphan nuclear receptor NR1I3, nuclear receptor coactivator 1 isoform 1
Authors:Xu, R.X., Lambert, M.H., Wisely, B.B., Warren, E.N., Weinert, E.E., Waitt, G.M., Williams, J.D., Moore, L.B., Willson, T.M., Moore, J.T.
Deposit date:2004-10-27
Release date:2004-12-28
Modification date:2009-02-24
Cite:A Structural Basis for Constitutive Activity in the Human CAR/RXRalpha Heterodimer.
Mol.Cell, 16, 2004
1XVP
CRYSTAL STRUCTURE OF CAR/RXR HETERODIMER BOUND WITH SRC1 PEPTIDE, FATTY ACID AND CITCO
Descriptor:Orphan nuclear receptor NR1I3, Retinoic acid receptor RXR-alpha, nuclear receptor coactivator 1 isoform 1
Authors:Xu, R.X., Lambert, M.H., Wisely, B.B., Warren, E.N., Weinert, E.E., Waitt, G.M., Williams, J.D., Moore, L.B., Willson, T.M., Moore, J.T.
Deposit date:2004-10-28
Release date:2004-12-28
Modification date:2009-02-24
Cite:A Structural Basis for Constitutive Activity in the Human CAR/RXRalpha Heterodimer.
Mol.Cell, 16, 2004
1Z5X
HEMIPTERAN ECDYSONE RECEPTOR LIGAND-BINDING DOMAIN COMPLEXED WITH PONASTERONE A
Descriptor:Ultraspiracle protein (USP) a homologue of RXR, Ecdysone receptor ligand binding subunit
Authors:Carmichael, J.A., Lawrence, M.C., Graham, L.D., Pilling, P.A., Epa, V.C., Noyce, L., Lovrecz, G., Winkler, D.A., Pawlak-Skrzecz, A.
Deposit date:2005-03-21
Release date:2005-04-05
Modification date:2009-02-24
Cite:The X-ray structure of a hemipteran ecdysone receptor ligand-binding domain: comparison with a lepidopteran ecdysone receptor ligand-binding domain and implications for insecticide design.
J.Biol.Chem., 280, 2005
2ACL
LIVER X-RECEPTOR ALPHA LIGAND BINDING DOMAIN WITH SB313987
Descriptor:Retinoic acid receptor RXR-alpha, Oxysterols receptor LXR-alpha
Authors:Jaye, M.C., Krawiec, J.A., Campobasso, N., Smallwood, A., Qiu, C., Lu, Q., Kerrigan, J.J.
Deposit date:2005-07-19
Release date:2005-09-20
Modification date:2009-02-24
Cite:Discovery of substituted maleimides as liver x receptor agonists and determination of a ligand-bound crystal structure.
J.Med.Chem., 48, 2005
2BJ4
ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A PHAGE-DISPLAY DERIVED PEPTIDE ANTAGONIST
Descriptor:ESTROGEN RECEPTOR, PEPTIDE ANTAGONIST
Authors:Kong, E., Heldring, N., Gustafsson, J.A., Treuter, E., Hubbard, R.E., Pike, A.C.W.
Deposit date:2005-01-28
Release date:2005-02-16
Modification date:2011-07-13
Cite:Delineation of a Unique Protein-Protein Interaction Site on the Surface of the Estrogen Receptor
Proc.Natl.Acad.Sci.USA, 102, 2005
2JFA
ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH AN AFFINITY-SELECTED COREPRESSOR PEPTIDE
Descriptor:ESTROGEN RECEPTOR, COREPRESSOR PEPTIDE
Authors:Heldring, N., Pawson, T., Mcdonnell, D., Treuter, E., Gustafsson, J.A., Pike, A.C.W.
Deposit date:2007-01-29
Release date:2007-02-20
Modification date:2011-07-13
Cite:Structural Insights Into Corepressor Recognition by Antagonist-Bound Estrogen Receptors.
J.Biol.Chem., 282, 2007
2NXX
CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAINS OF THE T.CASTANEUM (COLEOPTERA) HETERODIMER ECRUSP BOUND TO PONASTERONE A
Descriptor:Ultraspiracle (USP, NR2B4), Ecdysone Receptor (EcR, NRH1)
Authors:Iwema, T., Billas, I., Moras, D.
Deposit date:2006-11-20
Release date:2007-10-02
Modification date:2009-02-24
Cite:Structural and functional characterization of a novel type of ligand-independent RXR-USP receptor.
Embo J., 26, 2007
2Q59
CRYSTAL STRUCTURE OF PPARGAMMA LBD BOUND TO FULL AGONIST MRL20
Descriptor:Peroxisome Proliferator-Activated Receptor gamma, ligand binding domain
Authors:Bruning, J.B., Nettles, K.W.
Deposit date:2007-05-31
Release date:2007-10-23
Modification date:2011-07-13
Cite:Partial Agonists Activate PPARgamma Using a Helix 12 Independent Mechanism
Structure, 15, 2007
2QA8
CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN MUTANT 537S COMPLEXED WITH GENISTEIN
Descriptor:Estrogen receptor, nuclear receptor coactivator 2
Authors:Nettles, K.W., Bruning, J.B., Nowak, J., Sharma, S.K., Hahm, J.B., Shi, Y., Kulp, K., Hochberg, R.B., Zhou, H., Katzenellenbogen, J.A., Katzenellenbogen, B.S., Kim, Y., Joachmiak, A., Greene, G.L.
Deposit date:2007-06-14
Release date:2008-03-18
Modification date:2011-07-13
Cite:NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QZO
CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN COMPLEXED WITH WAY-169916
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2
Authors:Bruning, J.B., Gil, G., Nowak, J., Katzenellenbogen, J., Nettles, K.W.
Deposit date:2007-08-16
Release date:2008-08-26
Modification date:2011-07-13
Cite:Coupling of receptor conformation and ligand orientation determine graded activity.
Nat.Chem.Biol., 6, 2010
2R40
CRYSTAL STRUCTURE OF 20E BOUND ECR/USP
Descriptor:Crystal structure of 20E bound EcR/USP
Authors:Moras, D., Billas, I.M.L., Browning, C.
Deposit date:2007-08-30
Release date:2007-10-02
Modification date:2011-07-13
Cite:Critical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone Receptor
J.Biol.Chem., 282, 2007
2VV1
HPPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH 4-HDHA
Descriptor:PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
Authors:Itoh, T., Fairall, L., Schwabe, J.W.R.
Deposit date:2008-06-02
Release date:2008-08-19
Modification date:2012-06-06
Cite:Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
2VV4
HPPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH 6-OXOOTE
Descriptor:PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
Authors:Itoh, T., Fairall, L., Schwabe, J.W.R.
Deposit date:2008-06-02
Release date:2008-08-19
Modification date:2012-06-06
Cite:Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
3A9E
CRYSTAL STRUCTURE OF A MIXED AGONIST-BOUND RAR-ALPHA AND ANTAGONIST-BOUND RXR-ALPHA HETERODIMER LIGAND BINDING DOMAINS
Descriptor:Retinoic acid receptor RXR-alpha, Retinoic acid receptor alpha, 13-mer (LXXLL motif) from Nuclear receptor coactivator 2
Authors:Sato, Y., Duclaud, S., Peluso-Iltis, C., Poussin, P., Moras, D., Rochel, N.
Deposit date:2009-10-24
Release date:2010-10-06
Modification date:2013-10-30
Cite:The Phantom Effect of the Rexinoid LG100754: structural and functional insights
Plos One, 5, 2010
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