PDB keyword search results

2ONL
CRYSTAL STRUCTURE OF THE P38A-MAPKAP KINASE 2 HETERODIMER
Descriptor:Mitogen-activated protein kinase 14 (E.C.2.7.11.24), MAP kinase-activated protein kinase 2 (E.C.2.7.11.1)
Authors:Ter Haar, E.
Deposit date:2007-01-24
Release date:2007-02-06
Modification date:2009-02-24
Cite:Crystal structure of the P38alpha-MAPKAP kinase 2 heterodimer.
J.Biol.Chem., 282, 2007
2OZA
STRUCTURE OF P38ALPHA COMPLEX
Descriptor:MAP kinase-activated protein kinase 2 (E.C.2.7.11.1)/Mitogen-activated protein kinase 14 (E.C.2.7.11.24)
Authors:White, A., Pargellis, C.A., Studts, J.M., Werneburg, B.G., Farmer II, B.T.
Deposit date:2007-02-25
Release date:2007-04-03
Modification date:2009-02-24
Cite:Molecular basis of MAPK-activated protein kinase 2:p38 assembly
Proc.Natl.Acad.Sci.Usa, 104, 2007
3O7L
CRYSTAL STRUCTURE OF PHOSPHOLAMBAN (1-19):PKA C-SUBUNIT:AMP-PNP:MG2+ COMPLEX
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha (E.C.2.7.11.11), Cardiac phospholamban
Authors:Cheng, C.Y., Taylor, S.S.
Deposit date:2010-07-30
Release date:2010-10-06
Modification date:2010-12-01
Cite:Dynamics connect substrate recognition to catalysis in protein kinase A.
Nat.Chem.Biol., 6, 2010
4KIK
HUMAN IKB KINASE BETA
Descriptor:Inhibitor of nuclear factor kappa-B kinase subunit beta (E.C.2.7.11.10)
Authors:Liu, S., Mosyak, L.
Deposit date:2013-05-02
Release date:2013-06-26
Modification date:2013-08-28
Cite:Crystal Structure of a Human I kappa B Kinase beta Asymmetric Dimer.
J.Biol.Chem., 288, 2013
1A06
CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT
Descriptor:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE
Authors:Kuriyan, J., Goldberg, J.
Deposit date:1997-12-09
Release date:1998-04-08
Modification date:2009-02-24
Cite:Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I.
Cell(Cambridge,Mass.), 84, 1996
1A9U
THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580
Descriptor:MAP KINASE P38, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE
Authors:Wang, Z., Canagarajah, B., Boehm, J.C., Kassis, S., Cobb, M.H., Young, P.R., Abdel-Meguid, S., Adams, J.L., Goldsmith, E.J.
Deposit date:1998-04-10
Release date:1999-04-20
Modification date:2009-02-24
Cite:Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1APM
2.0 ANGSTROM REFINED CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH A PEPTIDE INHIBITOR AND DETERGENT
Descriptor:CAMP-DEPENDENT PROTEIN KINASE (E.C.2.7.1.37) (C/APK) (CATALYTIC SUBUNIT) "ALPHA" ISOENZYME MUTANT WITH SER 139 REPLACED BY ALA (S139A) COMPLEX WITH THE PEPTIDE INHIBITOR PKI(5-24) AND THE DETERGENT MEGA-8
Authors:Knighton, D.R., Bell, S.M., Zheng, J., Teneyck, L.F., Xuong, N.-H., Taylor, S.S., Sowadski, J.M.
Deposit date:1993-01-18
Release date:1993-04-15
Modification date:2009-02-24
Cite:2.0 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with a peptide inhibitor and detergent.
Acta Crystallogr.,Sect.D, 49, 1993
1AQ1
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR STAUROSPORINE
Descriptor:CYCLIN-DEPENDENT PROTEIN KINASE 2, STAUROSPORINE
Authors:Endicott, J.A., Noble, M.E.M., Johnson, L.N., Lawrie, A., Tunnah, P., Brown, N.R.
Deposit date:1997-08-05
Release date:1997-11-12
Modification date:2009-02-24
Cite:Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2.
Nat.Struct.Biol., 4, 1997
1ATP
2.2 ANGSTROM REFINED CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH MNATP AND A PEPTIDE INHIBITOR
Descriptor:CAMP-DEPENDENT PROTEIN KINASE (E.C.2.7.1.37) (C/APK) (CATALYTIC SUBUNIT) COMPLEX WITH THE PEPTIDE INHIBITOR PKI(5-24) AND MNATP (A TERNARY COMPLEX OF CAPK)
Authors:Zheng, J., Trafny, E.A., Knighton, D.R., Xuong, N.-H., Taylor, S.S., Teneyck, L.F., Sowadski, J.M.
Deposit date:1993-01-08
Release date:1993-04-15
Modification date:2009-02-24
Cite:2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor.
Acta Crystallogr.,Sect.D, 49, 1993
1B38
HUMAN CYCLIN-DEPENDENT KINASE 2
Descriptor:CELL DIVISION PROTEIN KINASE 2
Authors:Brown, N.R., Noble, M.E.M., Lawrie, A.M., Morris, M.C., Tunnah, P., Divita, G., Johnson, L.N., Endicott, J.A.
Deposit date:1998-12-17
Release date:1998-12-23
Modification date:2009-02-24
Cite:Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity.
J.Biol.Chem., 274, 1999
1B39
HUMAN CYCLIN-DEPENDENT KINASE 2 PHOSPHORYLATED ON THR 160
Descriptor:CELL DIVISION PROTEIN KINASE 2
Authors:Brown, N.R., Noble, M.E.M., Lawrie, A.M., Morris, M.C., Tunnah, P., Divita, G., Johnson, L.N., Endicott, J.A.
Deposit date:1998-12-17
Release date:1998-12-23
Modification date:2009-02-24
Cite:Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity.
J.Biol.Chem., 274, 1999
1BI7
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX
Descriptor:CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR
Authors:Russo, A.A., Tong, L., Lee, J.O., Jeffrey, P.D., Pavletich, N.P.
Deposit date:1998-06-22
Release date:1999-01-13
Modification date:2009-02-24
Cite:Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
1BI8
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX
Descriptor:CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR
Authors:Russo, A.A., Tong, L., Lee, J.O., Jeffrey, P.D., Pavletich, N.P.
Deposit date:1998-06-22
Release date:1999-01-13
Modification date:2009-02-24
Cite:Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
1BKX
A BINARY COMPLEX OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND ADENOSINE FURTHER DEFINES CONFORMATIONAL FLEXIBILITY
Descriptor:CAMP-DEPENDENT PROTEIN KINASE, ADENOSINE-5'-MONOPHOSPHATE
Authors:Narayana, N., Cox, S., Xuong, N., Ten Eyck, L.F., Taylor, S.S.
Deposit date:1997-07-01
Release date:1998-03-18
Modification date:2009-02-24
Cite:A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility.
Structure, 5, 1997
1BL6
THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB216995
Descriptor:PROTEIN (MAP KINASE P38) MUTANT (19 RESIDUES INSERTED AT N-TERMINUS)
Authors:Wang, Z., Canagarajah, B.J., Boehm, J.C., Kassis, S., Cobb, M.H., Young, P.R., Abdel-Meguid, S., Adams, J.L., Goldsmith, E.J.
Deposit date:1998-07-11
Release date:1999-07-26
Modification date:2009-02-24
Cite:Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BL7
THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB220025
Descriptor:PROTEIN (MAP KINASE P38) MUTANT (19 RESIDUES INSERTED AT N-TERMINUS)
Authors:Wang, Z., Canagarajah, B.J., Boehm, J.C., Kassis, S., Cobb, M.H., Young, P.R., Abdel-Meguid, S., Adams, J.L., Goldsmith, E.J.
Deposit date:1998-07-23
Release date:1999-07-26
Modification date:2009-02-24
Cite:Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BLX
P19INK4D/CDK6 COMPLEX
Descriptor:CYCLIN-DEPENDENT KINASE 6, P19INK4D
Authors:Brotherton, D.H., Dhanaraj, V., Wick, S., Brizuela, L., Domaille, P.J., Volyanik, E., Xu, X., Parisini, E., Smith, B.O., Archer, S.J., Serrano, M., Brenner, S.L., Blundell, T.L., Laue, E.D.
Deposit date:1998-07-21
Release date:1999-06-01
Modification date:2009-02-24
Cite:Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d.
Nature, 395, 1998
1BMK
THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB218655
Descriptor:PROTEIN (MAP KINASE P38) MUTANT (19 RESIDUES INSERTED AT N-TERMINUS)
Authors:Wang, Z., Canagarajah, B., Boehm, J.C., Kassis, S., Cobb, M.H., Young, P.R., Abdel- Meguid, S., Adams, J.L., Goldsmith, E.J.
Deposit date:1998-07-23
Release date:1999-07-23
Modification date:2009-02-24
Cite:Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BUH
CRYSTAL STRUCTURE OF THE HUMAN CDK2 KINASE COMPLEX WITH CELL CYCLE-REGULATORY PROTEIN CKSHS1
Descriptor:PROTEIN (CDK2 HUMAN)
Authors:Bourne, Y., Tainer, J.A.
Deposit date:1998-09-03
Release date:1998-09-09
Modification date:2009-02-24
Cite:Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1.
Cell(Cambridge,Mass.), 84, 1996
1BX6
CRYSTAL STRUCTURE OF THE POTENT NATURAL PRODUCT INHIBITOR BALANOL IN COMPLEX WITH THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:CAMP-DEPENDENT PROTEIN KINASE, BALANOL
Authors:Narayana, N., Xuong, N.-H., Ten Eyck, L.F., Taylor, S.S.
Deposit date:1998-10-13
Release date:1999-04-27
Modification date:2009-02-24
Cite:Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase.
Biochemistry, 38, 1999
1CDK
CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT (E.C.2.7.1.37) (PROTEIN KINASE A) COMPLEXED WITH PROTEIN KINASE INHIBITOR PEPTIDE FRAGMENT 5-24 (PKI(5-24) ISOELECTRIC VARIANT CA) AND MN2+ ADENYLYL IMIDODIPHOSPHATE (MNAMP-PNP) AT PH 5.6 AND 7C AND 4C
Descriptor:CAMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MYRISTIC ACID
Authors:Bossemeyer, D., Engh, R.A., Kinzel, V., Ponstingl, H., Huber, R.
Deposit date:1994-07-04
Release date:1995-10-15
Modification date:2012-08-01
Cite:Phosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24).
EMBO J., 12, 1993
1CKI
RECOMBINANT CASEIN KINASE I DELTA TRUNCATION MUTANT CONTAINING RESIDUES 1-317
Descriptor:CASEIN KINASE I DELTA
Authors:Longenecker, K.L., Roach, P.J., Hurley, T.D.
Deposit date:1995-08-25
Release date:1995-12-07
Modification date:2009-02-24
Cite:Three-dimensional structure of mammalian casein kinase I: molecular basis for phosphate recognition.
J.Mol.Biol., 257, 1996
1CKJ
CASEIN KINASE I DELTA TRUNCATION MUTANT CONTAINING RESIDUES 1-317 COMPLEX WITH BOUND TUNGSTATE
Descriptor:RECOMBINANT CASEIN KINASE I DELTA
Authors:Longenecker, K.L., Roach, P.J., Hurley, T.D.
Deposit date:1995-08-25
Release date:1995-12-07
Modification date:2009-02-24
Cite:Three-dimensional structure of mammalian casein kinase I: molecular basis for phosphate recognition.
J.Mol.Biol., 257, 1996
1CKP
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR PURVALANOL B
Descriptor:PROTEIN (CYCLIN-DEPENDENT PROTEIN KINASE 2) (2.7.1.37)
Authors:Gray, N.S., Thunnissen, A.M.W.H., Schultz, P.G., Kim, S.H.
Deposit date:1998-07-14
Release date:1999-01-13
Modification date:2010-03-31
Cite:Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.
Science, 281, 1998
1CM8
PHOSPHORYLATED MAP KINASE P38-GAMMA
Descriptor:MAP KINASE P38-GAMMA
Authors:Bellon, S., Fitzgibbon, M.J., Fox, T., Hsiao, H.M., Wilson, K.P.
Deposit date:1999-05-17
Release date:2000-05-17
Modification date:2009-02-24
Cite:The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation.
Structure Fold.Des., 7, 1999
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