PDB keyword search results

2CLQ
STRUCTURE OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (E.C.2.7.11.25)
Authors:Bunkoczi, G., Salah, E., Fedorov, O., Pike, A., Gileadi, O., Von Delft, F., Arrowsmith, C., Edwards, A., Sundstrom, M., Weigelt, J., Knapp, S.
Deposit date:2006-04-28
Release date:2006-05-09
Modification date:2011-07-13
Cite:Structural and Functional Characterization of the Human Protein Kinase Ask1.
Structure, 15, 2007
2CMW
STRUCTURE OF HUMAN CASEIN KINASE 1 GAMMA-1 IN COMPLEX WITH 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE (CASP TARGET)
Descriptor:CASEIN KINASE I ISOFORM GAMMA-1 (E.C.2.7.11.1)
Authors:Bunkoczi, G., Rellos, P., Das, S., Savitsky, P., Niesen, F., Sobott, F., Fedorov, O., Pike, A.C.W., Von Delft, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Weigelt, J., Knapp, S.
Deposit date:2006-05-15
Release date:2006-06-15
Modification date:2011-07-13
Cite:Structure of Human Casein Kinase 1 Gamma-1 in Complex with 2-(2-Hydroxyethylamino)-6-(3-Chloroanilino)-9-Isopropylpurine (Casp Target)
To be Published
2NRU
CRYSTAL STRUCTURE OF IRAK-4
Descriptor:Interleukin-1 receptor-associated kinase 4 (E.C.2.7.11.1)
Authors:Wang, Z., Liu, J., Walker, N.P.C.
Deposit date:2006-11-02
Release date:2006-12-12
Modification date:2009-02-24
Cite:Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper.
Structure, 14, 2006
2NRY
CRYSTAL STRUCTURE OF IRAK-4
Descriptor:interleukin-1 receptor-associated kinase 4 (E.C.2.7.11.1)
Authors:Wang, Z., Liu, J., Walker, N.P.C.
Deposit date:2006-11-02
Release date:2006-12-12
Modification date:2009-02-24
Cite:Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper.
Structure, 14, 2006
2O8Y
APO IRAK4 KINASE DOMAIN
Descriptor:Interleukin-1 receptor-associated kinase 4 (E.C.2.7.11.1)
Authors:Boriack-Sjodin, P.A., Mol, C.
Deposit date:2006-12-12
Release date:2007-12-25
Modification date:2009-02-24
Cite:Crystal structures of the apo and inhibited IRAK4 kinase domain
To be Published
2OIB
CRYSTAL STRUCTURE OF IRAK4 KINASE DOMAIN APO FORM
Descriptor:Interleukin-1 receptor-associated kinase 4 (E.C.2.7.11.1)
Authors:Kuglstatter, A., Villasenor, A.G., Browner, M.F.
Deposit date:2007-01-10
Release date:2007-03-20
Modification date:2009-02-24
Cite:Cutting Edge: IL-1 Receptor-Associated Kinase 4 Structures Reveal Novel Features and Multiple Conformations.
J.Immunol., 178, 2007
2OIC
CRYSTAL STRUCTURE OF IRAK4 KINASE DOMAIN COMPLEXED WITH STAUROSPORINE
Descriptor:Interleukin-1 receptor-associated kinase 4 (E.C.2.7.11.1)
Authors:Kuglstatter, A., Villasenor, A.G., Browner, M.F.
Deposit date:2007-01-10
Release date:2007-03-20
Modification date:2009-02-24
Cite:Cutting Edge: IL-1 Receptor-Associated Kinase 4 Structures Reveal Novel Features and Multiple Conformations.
J.Immunol., 178, 2007
2OID
CRYSTAL STRUCTURE OF IRAK4 KINASE DOMAIN COMPLEXED WITH AMPPNP
Descriptor:Interleukin-1 receptor-associated kinase 4 (E.C.2.7.11.1)
Authors:Kuglstatter, A., Villasenor, A.G., Browner, M.F.
Deposit date:2007-01-10
Release date:2007-03-20
Modification date:2009-02-24
Cite:Cutting Edge: IL-1 Receptor-Associated Kinase 4 Structures Reveal Novel Features and Multiple Conformations.
J.Immunol., 178, 2007
3COK
CRYSTAL STRUCTURE OF PLK4 KINASE
Descriptor:Serine/threonine-protein kinase PLK4 (E.C.2.7.11.21)
Authors:Atwell, S., Burley, S.K., Houle, A., Leon, B., Pelletier, L.A., Sauder, J.M., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2008-03-28
Release date:2008-04-15
Modification date:2009-06-09
Cite:Crystal structure of PLK4 kinase.
To be Published
3E7E
STRUCTURE AND SUBSTRATE RECRUITMENT OF THE HUMAN SPINDLE CHECKPOINT KINASE BUB
Descriptor:Mitotic checkpoint serine/threonine-protein kinase BUB1 (E.C.2.7.11.1)
Authors:Kang, J., Yang, M., Li, B., Qi, W., Zhang, C., Shokat, K., Tomchick, D.R., Machius, M., Yu, H.
Deposit date:2008-08-18
Release date:2008-11-25
Modification date:2011-07-13
Cite:Structure and substrate recruitment of the human spindle checkpoint kinase Bub1.
Mol.Cell, 32, 2008
3LM0
CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE KINASE 17B (STK17B)
Descriptor:Serine/threonine-protein kinase 17B (E.C.2.7.11.1)
Authors:Ugochukwu, E., Soundararajan, M., Rellos, P., Fedorov, O., Phillips, C., Wang, J., Hapka, E., Filippakopoulos, P., Chaikuad, A., Pike, A.C.W., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2010-01-29
Release date:2010-03-16
Modification date:2011-07-13
Cite:

3LM5
CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE KINASE 17B (STK17B) IN COMPLEX WITH QUERCETIN
Descriptor:---
Authors:Ugochukwu, E., Soundararajan, M., Rellos, P., Fedorov, O., Phillips, C., Wang, J., Hapka, E., Filippakopoulos, P., Chaikuad, A., Pike, A.C.W., Carpenter, L., Vollmar, M., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2010-01-29
Release date:2010-03-16
Modification date:2011-07-13
Cite:

3MTF
CRYSTAL STRUCTURE OF THE ACVR1 KINASE IN COMPLEX WITH A 2-AMINOPYRIDINE INHIBITOR
Descriptor:Activin receptor type-1 (E.C.2.7.11.30)
Authors:Chaikuad, A., Sanvitale, C., Cooper, C., Mahajan, P., Daga, N., Petrie, K., Alfano, I., Canning, P., Krojer, T., Vollmar, M., Knapp, S., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)
Deposit date:2010-04-30
Release date:2010-06-23
Cite:Crystal structure of the ACVR1 kinase in complex with a 2-aminopyridine inhibitor
To be Published
3MY0
CRYSTAL STRUCTURE OF THE ACVRL1 (ALK1) KINASE DOMAIN BOUND TO LDN-193189
Descriptor:Serine/threonine-protein kinase receptor R3 (E.C.2.7.11.30)
Authors:Chaikuad, A., Alfano, I., Cooper, C., Mahajan, P., Daga, N., Sanvitale, C., Fedorov, O., Petrie, K., Savitsky, P., Gileadi, O., Sethi, R., Krojer, T., Muniz, J.R.C., Pike, A.C.W., Vollmar, M., Carpenter, C.P., Ugochukwu, E., Knapp, S., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)
Deposit date:2010-05-08
Release date:2010-07-21
Cite:Crystal structure of the ACVRL1 (ALK1) kinase domain bound to LDN-193189
To be Published
3OOM
CRYSTAL STRUCTURE OF THE ACVR1 KINASE DOMAIN IN COMPLEX WITH THE IMIDAZO[1,2-B]PYRIDAZINE INHIBITOR K00507
Descriptor:Activin receptor type-1 (E.C.2.7.11.30)
Authors:Chaikuad, A., Sanvitale, C., Cooper, C., Mahajan, P., Daga, N., Petrie, K., Alfano, I., Gileadi, O., Fedorov, O., Allerston, C., Krojer, T., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)
Deposit date:2010-08-31
Release date:2010-10-13
Modification date:2010-10-27
Cite:Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00507
To be Published
3Q4U
CRYSTAL STRUCTURE OF THE ACVR1 KINASE DOMAIN IN COMPLEX WITH LDN-193189
Descriptor:Activin receptor type-1 (E.C.2.7.11.30)
Authors:Chaikuad, A., Sanvitale, C., Cooper, C.D.O., Mahajan, P., Daga, N., Petrie, K., Alfano, I., Gileadi, O., Fedorov, O., Allerston, C.K., Krojer, T., Vollmar, M., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)
Deposit date:2010-12-24
Release date:2011-02-09
Cite:Crystal structure of the ACVR1 kinase domain in complex with LDN-193189
To be Published
3VW6
CRYSTAL STRUCTURE OF HUMAN APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) WITH IMIDAZOPYRIDINE INHIBITOR
Descriptor:Mitogen-activated protein kinase kinase kinase 5 (E.C.2.7.11.25)
Authors:Terao, Y., Suzuki, H., Yoshikawa, M., Yashiro, H., Takekawa, S., Fujitani, Y., Okada, K., Inoue, Y., Yamamoto, Y., Nakagawa, H., Yao, S., Kawamoto, T., Uchikawa, O.
Deposit date:2012-08-06
Release date:2012-10-31
Cite:Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors
Bioorg.Med.Chem.Lett., 2012
4BF2
CRYSTAL STRUCTURES OF ASK1-INHIBITOR COMPLEXES
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (E.C.2.7.12.2)
Authors:Singh, O., Shillings, A., Craggs, P., Wall, I., Rowland, P., Skarzynski, T., Hobbs, C.I., Hardwick, P., Tanner, R., Blunt, M., Witty, D.R., Smith, K.J.
Deposit date:2013-03-13
Release date:2013-07-03
Modification date:2013-08-07
Cite:Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design.
Protein Sci., 22, 2013
4BGG
CRYSTAL STRUCTURE OF THE ACVR1 KINASE IN COMPLEX WITH LDN-213844
Descriptor:ACTIVIN RECEPTOR TYPE-1 (E.C.2.7.11.30)
Authors:Sanvitale, C., Canning, P., Cooper, C., Wang, Y., Mohedas, A.H., Choi, S., Yu, P.B., Cuny, G.D., Nowak, R., Coutandin, D., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)
Deposit date:2013-03-26
Release date:2013-04-10
Cite:Crystal Structure of the Acvr1 Kinase in Complex with Ldn-213844
To be Published
4BHN
CRYSTAL STRUCTURES OF ASK1-INHIBITOR COMPLEXES
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (E.C.2.7.11.25)
Authors:Singh, O., Shillings, A., Craggs, P., Wall, I., Rowland, P., Skarzynski, T., Hobbs, C.I., Hardwick, P., Tanner, R., Blunt, M., Witty, D.R., Smith, K.J.
Deposit date:2013-04-04
Release date:2013-07-03
Modification date:2013-08-07
Cite:Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design.
Protein Sci., 22, 2013
4BIB
CRYSTAL STRUCTURES OF ASK1-INHIBITOR COMPLEXES
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (E.C.2.7.11.25)
Authors:Singh, O., Shillings, A., Craggs, P., Wall, I., Rowland, P., Skarzynski, T., Hobbs, C.I., Hardwick, P., Tanner, R., Blunt, M., Witty, D.R., Smith, K.J.
Deposit date:2013-04-10
Release date:2013-07-03
Modification date:2013-08-07
Cite:Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design.
Protein Sci., 22, 2013
4BIC
CRYSTAL STRUCTURES OF ASK1-INHIBITOR COMPLEXES
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (E.C.2.7.11.25)
Authors:Singh, O., Shillings, A., Craggs, P., Wall, I., Rowland, P., Skarzynski, T., Hobbs, C.I., Hardwick, P., Tanner, R., Blunt, M., Witty, D.R., Smith, K.J.
Deposit date:2013-04-10
Release date:2013-07-03
Modification date:2013-08-07
Cite:Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design.
Protein Sci., 22, 2013
4BID
CRYSTAL STRUCTURES OF ASK1-INHIBITOR COMPLEXES
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (E.C.2.7.11.25)
Authors:Singh, O., Shillings, A., Craggs, P., Wall, I., Rowland, P., Skarzynski, T., Hobbs, C.I., Hardwick, P., Tanner, R., Blunt, M., Witty, D.R., Smith, K.J.
Deposit date:2013-04-10
Release date:2013-07-03
Modification date:2013-08-14
Cite:Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design.
Protein Sci., 22, 2013
4BIE
CRYSTAL STRUCTURES OF ASK1-INHIBITOR COMPLEXES
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (E.C.2.7.11.25)
Authors:Singh, O., Shillings, A., Craggs, P., Wall, I., Rowland, P., Skarzynski, T., Hobbs, C.I., Hardwick, P., Tanner, R., Blunt, M., Witty, D.R., Smith, K.J.
Deposit date:2013-04-10
Release date:2013-07-03
Modification date:2013-08-07
Cite:Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design.
Protein Sci., 22, 2013
4BWK
STRUCTURE OF NEUROSPORA CRASSA PAN3 PSEUDOKINASE
Descriptor:PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3
Authors:Christie, M., Boland, A., Huntzinger, E., Weichenrieder, O., Izaurralde, E.
Deposit date:2013-07-04
Release date:2013-08-21
Modification date:2013-08-28
Cite:Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins
Mol.Cell, 51, 2013
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