登録情報 | データベース: PDB / ID: 6k3f |
---|
タイトル | Crystal Structure of beta-Arrestin 2 in Complex with CXCR7 Phosphopeptide |
---|
要素 | - Beta-arrestin-2Arrestin beta 2
- Peptide from Atypical chemokine receptor 3ペプチド
|
---|
キーワード | SIGNALING PROTEIN / Complex |
---|
機能・相同性 | 機能・相同性情報
type 2A serotonin receptor binding / platelet activating factor receptor binding / postsynaptic signal transduction / positive regulation of synaptic transmission, dopaminergic / oculomotor nerve development / alpha-1A adrenergic receptor binding / follicle-stimulating hormone receptor binding / Activation of SMO / G alpha (s) signalling events / alpha-1B adrenergic receptor binding ...type 2A serotonin receptor binding / platelet activating factor receptor binding / postsynaptic signal transduction / positive regulation of synaptic transmission, dopaminergic / oculomotor nerve development / alpha-1A adrenergic receptor binding / follicle-stimulating hormone receptor binding / Activation of SMO / G alpha (s) signalling events / alpha-1B adrenergic receptor binding / follicle-stimulating hormone signaling pathway / positive regulation of mesenchymal stem cell migration / angiotensin receptor binding / C-X-C chemokine binding / positive regulation of cardiac muscle cell differentiation / C-X-C chemokine receptor activity / WNT5A-dependent internalization of FZD4 / protein kinase B binding / MAP2K and MAPK activation / Ub-specific processing proteases / negative regulation of toll-like receptor signaling pathway / C-C chemokine receptor activity / Cargo recognition for clathrin-mediated endocytosis / C-C chemokine binding / Clathrin-mediated endocytosis / scavenger receptor activity / negative regulation of interleukin-12 production / regulation of G protein-coupled receptor signaling pathway / negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage / positive regulation of calcium ion transport / arrestin family protein binding / G protein-coupled receptor internalization / type 1 angiotensin receptor binding / chemokine-mediated signaling pathway / adult walking behavior / Thrombin signalling through proteinase activated receptors (PARs) / Chemokine receptors bind chemokines / mitogen-activated protein kinase binding / positive regulation of epithelial cell apoptotic process / negative regulation of natural killer cell mediated cytotoxicity / negative regulation of interleukin-1 beta production / positive regulation of DNA biosynthetic process / negative regulation of release of cytochrome c from mitochondria / negative regulation of smooth muscle cell apoptotic process / detection of temperature stimulus involved in sensory perception of pain / negative regulation of interleukin-6 production / positive regulation of receptor internalization / negative regulation of tumor necrosis factor production / endocytic vesicle / D1 dopamine receptor binding / positive regulation of collagen biosynthetic process / 脈管形成 / coreceptor activity / negative regulation of canonical NF-kappaB signal transduction / クラスリン / negative regulation of protein ubiquitination / cell chemotaxis / transforming growth factor beta receptor signaling pathway / 14-3-3 protein binding / negative regulation of protein phosphorylation / G protein-coupled receptor binding / calcium-mediated signaling / regulation of protein phosphorylation / modulation of chemical synaptic transmission / receptor internalization / recycling endosome / エンドサイトーシス / positive regulation of peptidyl-tyrosine phosphorylation / protein transport / positive regulation of peptidyl-serine phosphorylation / G alpha (i) signalling events / positive regulation of cytosolic calcium ion concentration / cytoplasmic vesicle / postsynaptic membrane / proteasome-mediated ubiquitin-dependent protein catabolic process / basolateral plasma membrane / 血管新生 / negative regulation of neuron apoptotic process / 樹状突起スパイン / transcription by RNA polymerase II / positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / positive regulation of ERK1 and ERK2 cascade / molecular adaptor activity / protein ubiquitination / エンドソーム / 細胞接着 / エンドソーム / 免疫応答 / positive regulation of protein phosphorylation / G protein-coupled receptor signaling pathway / protein domain specific binding / negative regulation of cell population proliferation / external side of plasma membrane / signaling receptor binding / intracellular membrane-bounded organelle / glutamatergic synapse / ubiquitin protein ligase binding / protein-containing complex binding / positive regulation of gene expression / enzyme binding類似検索 - 分子機能 Atypical chemokine receptor 3 / : / Arrestin, conserved site / Arrestins signature. / アレスチン / Arrestin, N-terminal / Arrestin-like, N-terminal / Arrestin C-terminal-like domain / Arrestin (or S-antigen), N-terminal domain / Arrestin (or S-antigen), C-terminal domain ...Atypical chemokine receptor 3 / : / Arrestin, conserved site / Arrestins signature. / アレスチン / Arrestin, N-terminal / Arrestin-like, N-terminal / Arrestin C-terminal-like domain / Arrestin (or S-antigen), N-terminal domain / Arrestin (or S-antigen), C-terminal domain / Arrestin (or S-antigen), C-terminal domain / Arrestin-like, C-terminal / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family) / Immunoglobulin E-set類似検索 - ドメイン・相同性 Atypical chemokine receptor 3 / Beta-arrestin-2類似検索 - 構成要素 |
---|
生物種 | Rattus norvegicus (ドブネズミ) Homo sapiens (ヒト) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.3 Å |
---|
データ登録者 | Min, K.J. / Yoon, H.J. / Lee, H.H. |
---|
資金援助 | 韓国, 3件 組織 | 認可番号 | 国 |
---|
National Research Foundation (NRF, Korea) | 2015R1A5A1008958 | 韓国 | National Research Foundation (NRF, Korea) | 2018R1A2B2008142 | 韓国 | Ministry of Science, ICT and Future Planning (MSIP) | 2014M1A8A1049296 | 韓国 |
|
---|
引用 | ジャーナル: Structure / 年: 2020 タイトル: Crystal Structure of beta-Arrestin 2 in Complex with CXCR7 Phosphopeptide. 著者: Min, K. / Yoon, H.J. / Park, J.Y. / Baidya, M. / Dwivedi-Agnihotri, H. / Maharana, J. / Chaturvedi, M. / Chung, K.Y. / Shukla, A.K. / Lee, H.H. |
---|
履歴 | 登録 | 2019年5月18日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
---|
改定 1.0 | 2020年6月10日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2021年6月23日 | Group: Database references / Structure summary / カテゴリ: citation / citation_author / struct Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _struct.title |
---|
改定 1.2 | 2023年11月22日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
---|
|
---|