登録情報 データベース : PDB / ID : 4lnu 構造の表示 ダウンロードとリンクタイトル Nucleotide-free kinesin motor domain in complex with tubulin and a DARPin 要素Designed ankyrin repeat protein (DARPIN) D1 Kinesin-1 heavy chain キネシン Tubulin alpha chain Tubulin beta chain 詳細キーワード CELL CYCLE/MOTOR PROTEIN / ALPHA-TUBULIN / APO-KINESIN / BETA-TUBULIN (チューブリン) / DARPIN / KINESIN (キネシン) / MICROTUBULE (微小管) / TUBULIN (チューブリン) / CELL CYCLE-MOTOR PROTEIN complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
cytoplasm organization / cytolytic granule membrane / plus-end-directed vesicle transport along microtubule / anterograde neuronal dense core vesicle transport / anterograde dendritic transport of neurotransmitter receptor complex / mitocytosis / retrograde neuronal dense core vesicle transport / anterograde axonal protein transport / vesicle transport along microtubule / lysosome localization ... cytoplasm organization / cytolytic granule membrane / plus-end-directed vesicle transport along microtubule / anterograde neuronal dense core vesicle transport / anterograde dendritic transport of neurotransmitter receptor complex / mitocytosis / retrograde neuronal dense core vesicle transport / anterograde axonal protein transport / vesicle transport along microtubule / lysosome localization / positive regulation of potassium ion transport / natural killer cell mediated cytotoxicity / Kinesins / plus-end-directed microtubule motor activity / RHO GTPases activate KTN1 / stress granule disassembly / mitochondrion transport along microtubule / COPI-dependent Golgi-to-ER retrograde traffic / 繊毛 / centrosome localization / synaptic vesicle transport / kinesin complex / microtubule motor activity / microtubule-based movement / Insulin processing / centriolar satellite / Signaling by ALK fusions and activated point mutants / cytoplasmic microtubule / Nuclear events stimulated by ALK signaling in cancer / microtubule-based process / phagocytic vesicle / axon cytoplasm / MHC class II antigen presentation / regulation of membrane potential / cellular response to interleukin-4 / dendrite cytoplasm / 軸索誘導 / positive regulation of synaptic transmission, GABAergic / positive regulation of protein localization to plasma membrane / structural constituent of cytoskeleton / microtubule cytoskeleton organization / cellular response to type II interferon / double-stranded RNA binding / microtubule binding / vesicle / 微小管 / cadherin binding / GTPase activity / ubiquitin protein ligase binding / protein-containing complex binding / GTP binding / perinuclear region of cytoplasm / ATP hydrolysis activity / ミトコンドリア / ATP binding / 生体膜 / identical protein binding / 細胞質基質 / 細胞質 類似検索 - 分子機能 Kinesin motor domain / キネシン / Helix hairpin bin / Kinesin-like protein / Tubulin/FtsZ, C-terminal domain / Tubulin/FtsZ, GTPase domain / Ankyrin repeat-containing domain / Kinesin motor domain signature. / Kinesin motor domain, conserved site / Kinesin motor domain ... Kinesin motor domain / キネシン / Helix hairpin bin / Kinesin-like protein / Tubulin/FtsZ, C-terminal domain / Tubulin/FtsZ, GTPase domain / Ankyrin repeat-containing domain / Kinesin motor domain signature. / Kinesin motor domain, conserved site / Kinesin motor domain / Kinesin motor domain profile. / Kinesin motor, catalytic domain. ATPase. / Kinesin motor domain / 60s Ribosomal Protein L30; Chain: A; / Kinesin motor domain superfamily / Tubulin-beta mRNA autoregulation signal. / Alpha tubulin / Beta tubulin, autoregulation binding site / Beta tubulin / チューブリン / Tubulin, C-terminal / Tubulin C-terminal domain / Tubulin, conserved site / Tubulin subunits alpha, beta, and gamma signature. / Tubulin/FtsZ family, C-terminal domain / Tubulin/FtsZ-like, C-terminal domain / Tubulin/FtsZ, C-terminal / Tubulin/FtsZ, 2-layer sandwich domain / Tubulin/FtsZ family, GTPase domain / Tubulin/FtsZ family, GTPase domain / Tubulin/FtsZ, GTPase domain / Tubulin/FtsZ, GTPase domain superfamily / Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat / Αソレノイド / Helix Hairpins / P-loop containing nucleoside triphosphate hydrolase / ロスマンフォールド / 2-Layer Sandwich / Orthogonal Bundle / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta 類似検索 - ドメイン・相同性 GUANOSINE-5'-DIPHOSPHATE / グアノシン三リン酸 / Tubulin beta chain / Kinesin-1 heavy chain / Tubulin alpha chain 類似検索 - 構成要素生物種 Artificial gene (人工物) Homo sapiens (ヒト)Ovis aries (ヒツジ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.19 Å 詳細データ登録者 Cao, L. / Gigant, B. / Knossow, M. 引用ジャーナル : Nat Commun / 年 : 2014タイトル : The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement著者 : Cao, L. / Wang, W. / Jiang, Q. / Wang, C. / Knossow, M. / Gigant, B. 履歴 登録 2013年7月12日 登録サイト : RCSB / 処理サイト : PDBJ改定 1.0 2014年12月3日 Provider : repository / タイプ : Initial release改定 1.1 2023年11月8日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn / struct_ref_seq_dif / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr2_auth_seq_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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