登録情報 | データベース: PDB / ID: 8iee |
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タイトル | Crystal structure of nanobody VHH-31 with MERS-CoV RBD |
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要素 | |
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キーワード | VIRAL PROTEIN (ウイルスタンパク質) / MERS-CoV (MERSコロナウイルス) / nanobody (ナノボディ) / VIRAL PROTEIN-IMMUNE SYSTEM complex (ウイルス性) |
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機能・相同性 | 機能・相同性情報
endocytosis involved in viral entry into host cell / host cell endoplasmic reticulum-Golgi intermediate compartment membrane / receptor-mediated virion attachment to host cell / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / エンベロープ (ウイルス) / host cell plasma membrane / virion membrane / 生体膜類似検索 - 分子機能 Spike (S) protein S1 subunit, receptor-binding domain, MERS-CoV / Spike (S) protein S1 subunit, N-terminal domain, MERS-CoV-like / Spike glycoprotein S2, coronavirus, C-terminal / Coronavirus spike glycoprotein S2, intravirion / Betacoronavirus spike (S) glycoprotein S1 subunit N-terminal (NTD) domain profile. / Spike glycoprotein, N-terminal domain superfamily / Betacoronavirus spike (S) glycoprotein S1 subunit C-terminal (CTD) domain profile. / Spike glycoprotein, betacoronavirus / Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus / Spike S1 subunit, receptor binding domain superfamily, betacoronavirus ...Spike (S) protein S1 subunit, receptor-binding domain, MERS-CoV / Spike (S) protein S1 subunit, N-terminal domain, MERS-CoV-like / Spike glycoprotein S2, coronavirus, C-terminal / Coronavirus spike glycoprotein S2, intravirion / Betacoronavirus spike (S) glycoprotein S1 subunit N-terminal (NTD) domain profile. / Spike glycoprotein, N-terminal domain superfamily / Betacoronavirus spike (S) glycoprotein S1 subunit C-terminal (CTD) domain profile. / Spike glycoprotein, betacoronavirus / Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus / Spike S1 subunit, receptor binding domain superfamily, betacoronavirus / Betacoronavirus spike glycoprotein S1, receptor binding / Spike glycoprotein S1, N-terminal domain, betacoronavirus-like / Betacoronavirus-like spike glycoprotein S1, N-terminal / Spike glycoprotein S2, coronavirus, heptad repeat 1 / Spike glycoprotein S2, coronavirus, heptad repeat 2 / Coronavirus spike (S) glycoprotein S2 subunit heptad repeat 2 (HR2) region profile. / Coronavirus spike (S) glycoprotein S2 subunit heptad repeat 1 (HR1) region profile. / Spike glycoprotein S2 superfamily, coronavirus / Spike glycoprotein S2, coronavirus / Coronavirus spike glycoprotein S2 / Coronavirus spike glycoprotein S1, C-terminal / Coronavirus spike glycoprotein S1, C-terminal類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_virus.gif) ![](data/taxo/wicon/MERS-CoV_electron_micrograph1.jpg) Middle East respiratory syndrome-related coronavirus (MERSコロナウイルス)
![](img/tx_mammal.gif) ![](data/taxo/icon/Camelus_dromedarius_S.png) Camelus dromedarius (ヒトコブラクダ) |
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手法 | X線回折 / 分子置換 / 解像度: 3.21 Å |
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データ登録者 | Wang, X. / Tian, L. |
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資金援助 | 1件 |
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引用 | ジャーナル: To Be Published タイトル: Structures and neutralizing mechanisms of camel nanobodies targeting the receptor-binding domain of MERS-CoV spike glycoprotein 著者: Tian, L. / Wang, R. / Zhang, L. / Wang, X. |
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履歴 | 登録 | 2023年2月15日 | 登録サイト: PDBJ / 処理サイト: PDBC |
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改定 1.0 | 2024年2月28日 | Provider: repository / タイプ: Initial release |
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