登録情報 | データベース: PDB / ID: 8hib |
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タイトル | The crystal structure of Pygo2-LDB1-SSBP2 triple complex |
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要素 | - LIM domain-binding protein 1
- Pygopus homolog 2
- Single-stranded DNA-binding protein 2
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キーワード | TRANSCRIPTION / Protein binding / Complex |
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機能・相同性 | 機能・相同性情報
histone acetyltransferase regulator activity / Expression and translocation of olfactory receptors / regulation of kinase activity / cellular component assembly / negative regulation of erythrocyte differentiation / spermatid nucleus differentiation / regulation of mammary gland epithelial cell proliferation / positive regulation of hemoglobin biosynthetic process / cerebellar Purkinje cell differentiation / epithelial structure maintenance ...histone acetyltransferase regulator activity / Expression and translocation of olfactory receptors / regulation of kinase activity / cellular component assembly / negative regulation of erythrocyte differentiation / spermatid nucleus differentiation / regulation of mammary gland epithelial cell proliferation / positive regulation of hemoglobin biosynthetic process / cerebellar Purkinje cell differentiation / epithelial structure maintenance / beta-catenin-TCF complex / transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery / LIM domain binding / mammary gland development / gastrulation with mouth forming second / Cardiogenesis / lens development in camera-type eye / anterior/posterior axis specification / hair follicle development / regulation of focal adhesion assembly / roof of mouth development / cell leading edge / somatic stem cell population maintenance / positive regulation of cell adhesion / developmental growth / canonical Wnt signaling pathway / positive regulation of transcription elongation by RNA polymerase II / regulation of cell migration / kidney development / Deactivation of the beta-catenin transactivating complex / Formation of the beta-catenin:TCF transactivating complex / brain development / neuron differentiation / Wnt signaling pathway / Regulation of expression of SLITs and ROBOs / RUNX1 regulates transcription of genes involved in differentiation of HSCs / nervous system development / single-stranded DNA binding / histone binding / DNA-binding transcription factor binding / transcription regulator complex / transcription coactivator activity / RNA polymerase II-specific DNA-binding transcription factor binding / transcription by RNA polymerase II / cell adhesion / negative regulation of DNA-templated transcription / chromatin binding / chromatin / regulation of DNA-templated transcription / enzyme binding / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / protein homodimerization activity / protein-containing complex / DNA binding / nucleoplasm / nucleus / metal ion binding / cytoplasm類似検索 - 分子機能 Single-stranded DNA binding protein, SSDP / Sequence-specific single-strand DNA-binding protein / : / LIM-domain binding protein/SEUSS / LIM interaction domain / LIM-domain binding protein / LIM interaction domain (LID) / LIM interaction domain (LID) domain profile. / Lissencephaly type-1-like homology motif / LIS1 homology (LisH) motif profile. ...Single-stranded DNA binding protein, SSDP / Sequence-specific single-strand DNA-binding protein / : / LIM-domain binding protein/SEUSS / LIM interaction domain / LIM-domain binding protein / LIM interaction domain (LID) / LIM interaction domain (LID) domain profile. / Lissencephaly type-1-like homology motif / LIS1 homology (LisH) motif profile. / LIS1 homology motif / Zinc finger, PHD-type, conserved site / PHD-finger / Zinc finger PHD-type signature. / Zinc finger PHD-type profile. / Zinc finger, PHD-finger / Zinc finger, PHD-type / PHD zinc finger / Zinc finger, FYVE/PHD-type / Zinc finger, RING/FYVE/PHD-type類似検索 - ドメイン・相同性 Single-stranded DNA-binding protein 2 / LIM domain-binding protein 1 / Pygopus homolog 2類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.45 Å |
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データ登録者 | Wang, H.Y. / Yan, X.X. / Xu, W.Q. |
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資金援助 | 中国, 5件 組織 | 認可番号 | 国 |
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Chinese Academy of Sciences | XDB37030302 | 中国 | Chinese Academy of Sciences | 2021kf01 | 中国 | National Natural Science Foundation of China (NSFC) | 32000862 | 中国 | National Natural Science Foundation of China (NSFC) | 32171218 | 中国 | Other government | BX20200351 | |
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引用 | ジャーナル: To Be Published タイトル: The crystal structure of Pygo2-LDB1-SSBP2 triple complex 著者: Wang, H.Y. / Yan, X.X. / Xu, W.Q. |
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履歴 | 登録 | 2022年11月19日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2023年11月22日 | Provider: repository / タイプ: Initial release |
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