- PDB-8f5q: Crystal structure of human PCNA in complex with the PIP box of FBH1 -
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基本情報
登録情報
データベース: PDB / ID: 8f5q
タイトル
Crystal structure of human PCNA in complex with the PIP box of FBH1
要素
F-box DNA helicase 1
Proliferating cell nuclear antigen増殖細胞核抗原
キーワード
DNA BINDING PROTEIN (DNA結合タンパク質) / Complex
機能・相同性
機能・相同性情報
negative regulation of chromatin binding / response to intra-S DNA damage checkpoint signaling / positive regulation of deoxyribonuclease activity / dinucleotide insertion or deletion binding / PCNA-p21 complex / mitotic telomere maintenance via semi-conservative replication / DNA 3'-5' helicase / purine-specific mismatch base pair DNA N-glycosylase activity / positive regulation of DNA-directed DNA polymerase activity / 核ラミナ ...negative regulation of chromatin binding / response to intra-S DNA damage checkpoint signaling / positive regulation of deoxyribonuclease activity / dinucleotide insertion or deletion binding / PCNA-p21 complex / mitotic telomere maintenance via semi-conservative replication / DNA 3'-5' helicase / purine-specific mismatch base pair DNA N-glycosylase activity / positive regulation of DNA-directed DNA polymerase activity / 核ラミナ / MutLalpha complex binding / Polymerase switching / Telomere C-strand (Lagging Strand) Synthesis / DNA translocase activity / Processive synthesis on the lagging strand / PCNA complex / positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage / Removal of the Flap Intermediate / Processive synthesis on the C-strand of the telomere / Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) / Polymerase switching on the C-strand of the telomere / Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) / Transcription of E2F targets under negative control by DREAM complex / Removal of the Flap Intermediate from the C-strand / DNA catabolic process / replisome / SCF複合体 / response to L-glutamate / histone acetyltransferase binding / 3'-5' DNA helicase activity / DNA polymerase processivity factor activity / G1/S-Specific Transcription / leading strand elongation / replication fork processing / response to dexamethasone / nuclear replication fork / SUMOylation of DNA replication proteins / estrous cycle / PCNA-Dependent Long Patch Base Excision Repair / cyclin-dependent protein kinase holoenzyme complex / DNAミスマッチ修復 / DNA修復 / negative regulation of double-strand break repair via homologous recombination / response to cadmium ion / DNA polymerase binding / isomerase activity / epithelial cell differentiation / positive regulation of DNA repair / DNA helicase activity / Translesion synthesis by REV1 / base-excision repair, gap-filling / Translesion synthesis by POLK / Translesion synthesis by POLI / Gap-filling DNA repair synthesis and ligation in GG-NER / TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest / DNA複製 / positive regulation of DNA replication / male germ cell nucleus / liver regeneration / nuclear estrogen receptor binding / Recognition of DNA damage by PCNA-containing replication complex / Termination of translesion DNA synthesis / double-strand break repair via homologous recombination / Translesion Synthesis by POLH / HDR through Homologous Recombination (HRR) / Dual Incision in GG-NER / receptor tyrosine kinase binding / cellular response to hydrogen peroxide / Dual incision in TC-NER / Gap-filling DNA repair synthesis and ligation in TC-NER / cellular response to UV / cellular response to xenobiotic stimulus / E3 ubiquitin ligases ubiquitinate target proteins / response to estradiol / heart development / single-stranded DNA binding / double-stranded DNA binding / damaged DNA binding / chromosome, telomeric region / nuclear body / protein ubiquitination / positive regulation of protein phosphorylation / DNA修復 / 中心体 / DNA damage response / chromatin binding / クロマチン / protein-containing complex binding / enzyme binding / negative regulation of transcription by RNA polymerase II / ATP hydrolysis activity / extracellular exosome / 核質 / ATP binding / identical protein binding / 細胞核 類似検索 - 分子機能