[English] 日本語
![](img/lk-miru.gif)
- PDB-8cxi: Structures of Zika Virus in Complex with Antibodies Targeting E D... -
+
Open data
-
Basic information
Entry | Database: PDB / ID: 8cxi | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Title | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy | ||||||||||||
![]() |
| ||||||||||||
![]() | VIRUS/IMMUNE SYSTEM / ![]() | ||||||||||||
Function / homology | ![]() low-density lipoprotein particle receptor binding / regulation of protein-containing complex assembly / symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT2 activity / ribonucleoside triphosphate phosphatase activity / ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Similarity search - Function | ||||||||||||
Biological species | ![]() ![]() ![]() ![]() ![]() | ||||||||||||
Method | ![]() ![]() ![]() | ||||||||||||
![]() | Liu, W. / Zhang, X.K. / Gong, D.Y. / Dai, X.H. / Sharma, A. / Zhang, T.H. / Rey, F. / Zhou, Z.H. | ||||||||||||
Funding support | ![]()
| ||||||||||||
![]() | ![]() Title: Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy Authors: Liu, W. / Zhang, X.K. / Gong, D.Y. / Dai, X.H. / Sharma, A. / Zhang, T.H. / Rey, F. / Zhou, Z.H. | ||||||||||||
History |
|
-
Structure visualization
Structure viewer | Molecule: ![]() ![]() |
---|
-
Downloads & links
-
Download
PDBx/mmCIF format | ![]() | 573.2 KB | Display | ![]() |
---|---|---|---|---|
PDB format | ![]() | 355.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
---|
-Related structure data
Related structure data | ![]() 27058MC ![]() 8cxgC ![]() 8cxhC M: map data used to model this data C: citing same article ( |
---|---|
Similar structure data | Similarity search - Function & homology ![]() |
-
Links
-
Assembly
Deposited unit | ![]()
|
---|---|
1 |
|
-
Components
#1: Protein | Mass: 69326.820 Da / Num. of mol.: 3 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() ![]() #2: Protein | Mass: 379600.719 Da / Num. of mol.: 3 Source method: isolated from a genetically manipulated source Details: Model includes only small envelope protein M UNP residues 216-290 Source: (gene. exp.) ![]() ![]() ![]() ![]() ![]() #3: Antibody | Mass: 14858.386 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() #4: Antibody | Mass: 11633.908 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() #5: Polysaccharide | ![]() Source method: isolated from a genetically manipulated source Has ligand of interest | N | |
---|
-Experimental details
-Experiment
Experiment | Method: ![]() |
---|---|
EM experiment | Aggregation state: PARTICLE / 3D reconstruction method: ![]() |
-
Sample preparation
Component | Name: Zika virus![]() | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Source (natural) |
| ||||||||||||
Source (recombinant) | Organism: ![]() ![]() | ||||||||||||
Details of virus | Empty: NO / Enveloped: YES / Isolate: SPECIES / Type: VIRION | ||||||||||||
Buffer solution | pH: 7.4 | ||||||||||||
Specimen | Embedding applied: NO / Shadowing applied: NO / Staining applied![]() ![]() | ||||||||||||
Vitrification![]() | Cryogen name: ETHANE |
-
Electron microscopy imaging
Experimental equipment | ![]() Model: Titan Krios / Image courtesy: FEI Company |
---|---|
Microscopy | Model: FEI TITAN KRIOS |
Electron gun | Electron source![]() ![]() |
Electron lens | Mode: BRIGHT FIELD![]() |
Image recording | Electron dose: 26 e/Å2 / Film or detector model: GATAN K2 SUMMIT (4k x 4k) |
-
Processing
CTF correction![]() | Type: PHASE FLIPPING AND AMPLITUDE CORRECTION |
---|---|
3D reconstruction![]() | Resolution: 3.4 Å / Resolution method: FSC 0.143 CUT-OFF / Num. of particles: 1124970 / Symmetry type: POINT |