登録情報 | データベース: PDB / ID: 8bia |
---|
タイトル | Crystal structure of Scribble PDZ1 with PTHR |
---|
要素 | - Parathyroid hormone/parathyroid hormone-related peptide receptor
- Protein scribble homolog
|
---|
キーワード | PROTEIN BINDING (タンパク質) / Scribble (ドゥードゥルアート) / PTHR / PDZ domain (PDZドメイン) / cell polarity |
---|
機能・相同性 | 機能・相同性情報
neurotransmitter receptor transport postsynaptic membrane to endosome / extrinsic component of postsynaptic density membrane / establishment of T cell polarity / parathyroid hormone receptor activity / apoptotic process involved in morphogenesis / establishment of apical/basal cell polarity / cochlear nucleus development / synaptic vesicle targeting / Scrib-APC-beta-catenin complex / astrocyte cell migration ...neurotransmitter receptor transport postsynaptic membrane to endosome / extrinsic component of postsynaptic density membrane / establishment of T cell polarity / parathyroid hormone receptor activity / apoptotic process involved in morphogenesis / establishment of apical/basal cell polarity / cochlear nucleus development / synaptic vesicle targeting / Scrib-APC-beta-catenin complex / astrocyte cell migration / polarized epithelial cell differentiation / myelin sheath abaxonal region / neurotransmitter receptor transport, endosome to postsynaptic membrane / protein localization to adherens junction / cell-cell contact zone / mammary gland duct morphogenesis / post-anal tail morphogenesis / G protein-coupled peptide receptor activity / establishment or maintenance of epithelial cell apical/basal polarity / activation of GTPase activity / regulation of postsynaptic neurotransmitter receptor internalization / auditory receptor cell stereocilium organization / Class B/2 (Secretin family receptors) / osteoblast development / RND2 GTPase cycle / RND3 GTPase cycle / positive regulation of inositol phosphate biosynthetic process / positive regulation of receptor recycling / positive chemotaxis / receptor clustering / bone mineralization / RHOJ GTPase cycle / RHOQ GTPase cycle / negative regulation of activated T cell proliferation / G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger / peptide hormone binding / CDC42 GTPase cycle / synaptic vesicle endocytosis / 免疫シナプス / negative regulation of mitotic cell cycle / chondrocyte differentiation / signaling adaptor activity / cell maturation / bone resorption / Asymmetric localization of PCP proteins / skeletal system development / neural tube closure / 接着結合 / wound healing / adenylate cyclase-modulating G protein-coupled receptor signaling pathway / adenylate cyclase-activating G protein-coupled receptor signaling pathway / 細胞接着 / intracellular calcium ion homeostasis / : / 遊走 / cell-cell junction / positive regulation of type II interferon production / presynapse / 細胞結合 / lamellipodium / phospholipase C-activating G protein-coupled receptor signaling pathway / G alpha (s) signalling events / basolateral plasma membrane / in utero embryonic development / cell population proliferation / postsynaptic density / cell surface receptor signaling pathway / receptor complex / cadherin binding / positive regulation of apoptotic process / apical plasma membrane / G protein-coupled receptor signaling pathway / negative regulation of cell population proliferation / glutamatergic synapse / positive regulation of cell population proliferation / protein homodimerization activity / extracellular exosome / 核質 / 細胞核 / 細胞膜 / 細胞質類似検索 - 分子機能 GPCR, family 2, parathyroid hormone receptor / Leucine-rich repeats, bacterial type / ロイシンリッチリピート / G-protein coupled receptors family 2 signature 1. / Hormone receptor domain / GPCR, family 2, extracellular hormone receptor domain / G-protein coupled receptors family 2 profile 1. / Domain present in hormone receptors / GPCR family 2, extracellular hormone receptor domain superfamily / G-protein coupled receptors family 2 signature 2. ...GPCR, family 2, parathyroid hormone receptor / Leucine-rich repeats, bacterial type / ロイシンリッチリピート / G-protein coupled receptors family 2 signature 1. / Hormone receptor domain / GPCR, family 2, extracellular hormone receptor domain / G-protein coupled receptors family 2 profile 1. / Domain present in hormone receptors / GPCR family 2, extracellular hormone receptor domain superfamily / G-protein coupled receptors family 2 signature 2. / GPCR, family 2, secretin-like, conserved site / GPCR, family 2, secretin-like / 7 transmembrane receptor (Secretin family) / GPCR, family 2-like / G-protein coupled receptors family 2 profile 2. / ロイシンリッチリピート / Leucine-rich repeat, typical subtype / Leucine-rich repeats, typical (most populated) subfamily / Leucine-rich repeat profile. / PDZドメイン / ロイシンリッチリピート / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZドメイン / PDZ superfamily / Leucine-rich repeat domain superfamily類似検索 - ドメイン・相同性 リン酸塩 / Parathyroid hormone/parathyroid hormone-related peptide receptor / Protein scribble homolog類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.4 Å |
---|
データ登録者 | Stewart, B.Z. / Kvansakul, M. |
---|
資金援助 | オーストラリア, 2件 組織 | 認可番号 | 国 |
---|
National Health and Medical Research Council (NHMRC, Australia) | APP1103871 | オーストラリア | Australian Research Council (ARC) | FT130101349 | オーストラリア |
|
---|
引用 | ジャーナル: To Be Published タイトル: Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide 著者: Stewart, B.Z. / Caria, S. / Humbert, P.O. / Kvansakul, M. |
---|
履歴 | 登録 | 2022年11月2日 | 登録サイト: PDBE / 処理サイト: PDBE |
---|
改定 1.0 | 2023年11月15日 | Provider: repository / タイプ: Initial release |
---|
|
---|