登録情報 | データベース: PDB / ID: 8a6c |
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タイトル | 1 picosecond light activated crystal structure of bovine rhodopsin in Lipidic Cubic Phase |
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要素 | Rhodopsin ロドプシン |
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キーワード | MEMBRANE PROTEIN (膜タンパク質) / GPCR (Gタンパク質共役受容体) / Opsin |
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機能・相同性 | 機能・相同性情報
Opsins / VxPx cargo-targeting to cilium / rod bipolar cell differentiation / rod photoreceptor outer segment / sperm head plasma membrane / absorption of visible light / podosome assembly / opsin binding / The canonical retinoid cycle in rods (twilight vision) / : ... Opsins / VxPx cargo-targeting to cilium / rod bipolar cell differentiation / rod photoreceptor outer segment / sperm head plasma membrane / absorption of visible light / podosome assembly / opsin binding / The canonical retinoid cycle in rods (twilight vision) / : / G protein-coupled photoreceptor activity / photoreceptor inner segment membrane / G protein-coupled opsin signaling pathway / 11-cis retinal binding / cellular response to light stimulus / G protein-coupled receptor complex / Inactivation, recovery and regulation of the phototransduction cascade / thermotaxis / Activation of the phototransduction cascade / phototransduction, visible light / outer membrane / detection of temperature stimulus involved in thermoception / photoreceptor cell maintenance / arrestin family protein binding / photoreceptor outer segment membrane / G alpha (i) signalling events / phototransduction / photoreceptor outer segment / response to light stimulus / G-protein alpha-subunit binding / sperm midpiece / 視覚 / guanyl-nucleotide exchange factor activity / photoreceptor disc membrane / microtubule cytoskeleton organization / cell-cell junction / 遺伝子発現 / G protein-coupled receptor signaling pathway / ゴルジ体 / zinc ion binding / 生体膜 / identical protein binding / 細胞膜類似検索 - 分子機能 Rhodopsin, N-terminal / Amino terminal of the G-protein receptor rhodopsin / ロドプシン / Opsin / Visual pigments (opsins) retinal binding site / Visual pigments (opsins) retinal binding site. / Serpentine type 7TM GPCR chemoreceptor Srsx / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM ... Rhodopsin, N-terminal / Amino terminal of the G-protein receptor rhodopsin / ロドプシン / Opsin / Visual pigments (opsins) retinal binding site / Visual pigments (opsins) retinal binding site. / Serpentine type 7TM GPCR chemoreceptor Srsx / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family)類似検索 - ドメイン・相同性 アセチル基 / ラウリン酸 / (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate / パルミチン酸 / レチナール / ロドプシン類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) ![](data/taxo/icon/Bos_taurus_S.png) Bos taurus (ウシ) |
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手法 | X線回折 / 自由電子レーザー / 分子置換 / 解像度: 1.8 Å |
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データ登録者 | Gruhl, T. / Weinert, T. / Rodrigues, M.J. / Milne, C.J. / Ortolani, G. / Nass, K. / Nango, E. / Sen, S. / Johnson, P.J.M. / Cirelli, C. ...Gruhl, T. / Weinert, T. / Rodrigues, M.J. / Milne, C.J. / Ortolani, G. / Nass, K. / Nango, E. / Sen, S. / Johnson, P.J.M. / Cirelli, C. / Furrer, A. / Mous, S. / Skopintsev, P. / James, D. / Dworkowski, F. / Baath, P. / Kekilli, D. / Oserov, D. / Tanaka, R. / Glover, H. / Bacellar, C. / Bruenle, S. / Casadei, C.M. / Diethelm, A.D. / Gashi, D. / Gotthard, G. / Guixa-Gonzalez, R. / Joti, Y. / Kabanova, V. / Knopp, G. / Lesca, E. / Ma, P. / Martiel, I. / Muehle, J. / Owada, S. / Pamula, F. / Sarabi, D. / Tejero, O. / Tsai, C.J. / Varma, N. / Wach, A. / Boutet, S. / Tono, K. / Nogly, P. / Deupi, X. / Iwata, S. / Neutze, R. / Standfuss, J. / Schertler, G.F.X. / Panneels, V. |
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資金援助 | スイス, 2件 組織 | 認可番号 | 国 |
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Swiss National Science Foundation | 153145 | スイス | Swiss National Science Foundation | 192760 | スイス |
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引用 | ジャーナル: Nature / 年: 2023タイトル: Ultrafast structural changes direct the first molecular events of vision. 著者: Gruhl, T. / Weinert, T. / Rodrigues, M.J. / Milne, C.J. / Ortolani, G. / Nass, K. / Nango, E. / Sen, S. / Johnson, P.J.M. / Cirelli, C. / Furrer, A. / Mous, S. / Skopintsev, P. / James, D. / ...著者: Gruhl, T. / Weinert, T. / Rodrigues, M.J. / Milne, C.J. / Ortolani, G. / Nass, K. / Nango, E. / Sen, S. / Johnson, P.J.M. / Cirelli, C. / Furrer, A. / Mous, S. / Skopintsev, P. / James, D. / Dworkowski, F. / Bath, P. / Kekilli, D. / Ozerov, D. / Tanaka, R. / Glover, H. / Bacellar, C. / Brunle, S. / Casadei, C.M. / Diethelm, A.D. / Gashi, D. / Gotthard, G. / Guixa-Gonzalez, R. / Joti, Y. / Kabanova, V. / Knopp, G. / Lesca, E. / Ma, P. / Martiel, I. / Muhle, J. / Owada, S. / Pamula, F. / Sarabi, D. / Tejero, O. / Tsai, C.J. / Varma, N. / Wach, A. / Boutet, S. / Tono, K. / Nogly, P. / Deupi, X. / Iwata, S. / Neutze, R. / Standfuss, J. / Schertler, G. / Panneels, V.#1: ジャーナル: Biorxiv / 年: 2022タイトル: ULTRAFAST STRUCTURAL CHANGES DIRECT THE FIRST MOLECULAR EVENTS OF VISION 著者: Gruhl, T. / Weinert, T. / Rodrigues, M. / Milne, C.J. / Ortolani, G. / Nass, K. / Nango, E. / Sen, S. / Johnson, P.J.M. / Cirelli, C. / Furrer, A. / Mous, S. / Skopintsev, P. / James, D. / ...著者: Gruhl, T. / Weinert, T. / Rodrigues, M. / Milne, C.J. / Ortolani, G. / Nass, K. / Nango, E. / Sen, S. / Johnson, P.J.M. / Cirelli, C. / Furrer, A. / Mous, S. / Skopintsev, P. / James, D. / Dworkowski, F. / Bath, P. / Kekilli, D. / Ozerov, D. / Tanaka, R. / Glover, H. / Bacellar, C. / Brunle, S. / Casadei, C.M. / Diethelm, A.D. / Gashi, D. / Gotthard, G. / Guixa-Gonzalez, R. / Joti, Y. / Kabanova, V. / Knopp, G. / Lesca, E. / Ma, P. / Martiel, I. / Muhle, J. / Owada, S. / Pamula, F. / Sarabi, D. / Tejero, O. / Tsai, C.J. / Varma, N. / Wach, A. / Boutet, S. / Tono, K. / Nogly, P. / Deupi, X. / Iwata, S. / Neutze, R. / Standfuss, J. / Schertler, G.F. / Panneels, V. |
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履歴 | 登録 | 2022年6月17日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2023年3月29日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年4月5日 | Group: Database references / カテゴリ: citation / Item: _citation.pdbx_database_id_PubMed / _citation.title |
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改定 1.2 | 2023年4月12日 | Group: Database references / カテゴリ: citation Item: _citation.journal_volume / _citation.page_first / _citation.page_last |
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改定 1.3 | 2024年2月7日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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