+Open data
-Basic information
Entry | Database: PDB / ID: 6y31 | ||||||
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Title | NG domain of human SRP54 T117 deletion mutant | ||||||
Components | Signal recognition particle 54 kDa protein | ||||||
Keywords | RNA BINDING PROTEIN / SRP54 NG domain / Protein translocation / Severe congenital neutropenia / Disease mutant | ||||||
Function / homology | Function and homology information SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition / endoplasmic reticulum signal peptide binding / signal recognition particle, endoplasmic reticulum targeting / granulocyte differentiation / signal-recognition-particle GTPase / protein targeting to ER / SRP-dependent cotranslational protein targeting to membrane, translocation / 7S RNA binding / exocrine pancreas development / SRP-dependent cotranslational protein targeting to membrane ...SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition / endoplasmic reticulum signal peptide binding / signal recognition particle, endoplasmic reticulum targeting / granulocyte differentiation / signal-recognition-particle GTPase / protein targeting to ER / SRP-dependent cotranslational protein targeting to membrane, translocation / 7S RNA binding / exocrine pancreas development / SRP-dependent cotranslational protein targeting to membrane / SRP-dependent cotranslational protein targeting to membrane / ribonucleoprotein complex binding / neutrophil chemotaxis / GDP binding / nuclear speck / GTPase activity / GTP binding / endoplasmic reticulum / ATP hydrolysis activity / RNA binding / nucleus / cytosol / cytoplasm Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 4.001 Å | ||||||
Authors | Juaire, K.D. / Lapouge, K. / Becker, M.M.M. / Kotova, I. / Haas, M. / Carapito, R. / Wild, K. / Bahram, S. / Sinning, I. | ||||||
Funding support | Germany, 1items
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Citation | Journal: Structure / Year: 2021 Title: Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia. Authors: Juaire, K.D. / Lapouge, K. / Becker, M.M.M. / Kotova, I. / Michelhans, M. / Carapito, R. / Wild, K. / Bahram, S. / Sinning, I. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6y31.cif.gz | 465.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6y31.ent.gz | 391.9 KB | Display | PDB format |
PDBx/mmJSON format | 6y31.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/y3/6y31 ftp://data.pdbj.org/pub/pdb/validation_reports/y3/6y31 | HTTPS FTP |
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-Related structure data
Related structure data | 6y2zSC 6y30C 6y32C S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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