Entry Database : PDB / ID : 6iyl Structure visualization Downloads & linksTitle The structure of EntE with 3-cyanobenzoyl adenylate analog Components2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex Details Keywords LIGASE / adenylation / non-ribosomal peptide biosynthesisFunction / homology Function and homology informationFunction Domain/homology Component
(2,3-dihydroxybenzoyl)adenylate synthase / 2,3-dihydroxybenzoate-[aryl-carrier protein] ligase / enterobactin synthase / 2,3-dihydroxybenzoate--[aryl-carrier protein] ligase / 2,3-dihydroxybenzoate-serine ligase activity / enterobactin biosynthetic process / siderophore biosynthetic process / acyltransferase activity / ligase activity / ATP binding ... (2,3-dihydroxybenzoyl)adenylate synthase / 2,3-dihydroxybenzoate-[aryl-carrier protein] ligase / enterobactin synthase / 2,3-dihydroxybenzoate--[aryl-carrier protein] ligase / 2,3-dihydroxybenzoate-serine ligase activity / enterobactin biosynthetic process / siderophore biosynthetic process / acyltransferase activity / ligase activity / ATP binding / membrane / cytosol Similarity search - Function 2,3-dihydroxybenzoate-AMP ligase / ANL, N-terminal domain / ANL, N-terminal domain / AMP-binding enzyme, C-terminal domain / AMP-binding enzyme C-terminal domain / AMP-binding, conserved site / Putative AMP-binding domain signature. / AMP-dependent synthetase/ligase / AMP-binding enzyme, C-terminal domain superfamily / AMP-binding enzyme ... 2,3-dihydroxybenzoate-AMP ligase / ANL, N-terminal domain / ANL, N-terminal domain / AMP-binding enzyme, C-terminal domain / AMP-binding enzyme C-terminal domain / AMP-binding, conserved site / Putative AMP-binding domain signature. / AMP-dependent synthetase/ligase / AMP-binding enzyme, C-terminal domain superfamily / AMP-binding enzyme / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homology Chem-B1X / 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex / Enterobactin synthase component E Similarity search - ComponentBiological species Escherichia coli 1303 (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.56 Å DetailsAuthors Miyanaga, A. / Ishikawa, F. Funding support Japan, 2items Details Hide detailsOrganization Grant number Country Japan Society for the Promotion of Science 17H05438 Japan Japan Society for the Promotion of Science 16H06451 Japan
CitationJournal : Angew.Chem.Int.Ed.Engl. / Year : 2019Title : An Engineered Aryl Acid Adenylation Domain with an Enlarged Substrate Binding Pocket.Authors : Ishikawa, F. / Miyanaga, A. / Kitayama, H. / Nakamura, S. / Nakanishi, I. / Kudo, F. / Eguchi, T. / Tanabe, G. History Deposition Dec 17, 2018 Deposition site : PDBJ / Processing site : PDBJRevision 1.0 Apr 17, 2019 Provider : repository / Type : Initial releaseRevision 1.1 May 1, 2019 Group : Data collection / Database references / Category : citation / citation_author / Item : _citation.title / _citation_author.identifier_ORCIDRevision 1.2 May 29, 2019 Group : Data collection / Database references / Category : citation / citation_authorItem : _citation.journal_abbrev / _citation.journal_volume ... _citation.journal_abbrev / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation_author.identifier_ORCID Revision 1.3 Nov 22, 2023 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / refine_hist / struct_ncs_dom_lim Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _refine_hist.d_res_low / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
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