Entry | Database: PDB / ID: 6dxe |
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Title | Crystal structure of chalcone synthase from Arabidopsis thaliana - M64I F170S G173A S213G Q217A T270V C347S mutant |
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Components | Chalcone synthase |
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Keywords | TRANSFERASE / Thiolase / Flavonoid / Polyketide synthase |
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Function / homology | Function and homology information
regulation of anthocyanin biosynthetic process / chalcone synthase activity / chalcone synthase / naringenin-chalcone synthase activity / auxin polar transport / plant-type vacuole membrane / flavonoid biosynthetic process / response to jasmonic acid / polyketide biosynthetic process / response to auxin ...regulation of anthocyanin biosynthetic process / chalcone synthase activity / chalcone synthase / naringenin-chalcone synthase activity / auxin polar transport / plant-type vacuole membrane / flavonoid biosynthetic process / response to jasmonic acid / polyketide biosynthetic process / response to auxin / response to gravity / response to UV-B / response to wounding / response to oxidative stress / endoplasmic reticulum / nucleusSimilarity search - Function Chalcone/stilbene synthase, active site / Chalcone and stilbene synthases active site. / Chalcone/stilbene synthase, N-terminal / Polyketide synthase, type III / Chalcone/stilbene synthase, C-terminal / Chalcone and stilbene synthases, C-terminal domain / Chalcone and stilbene synthases, N-terminal domain / Thiolase/Chalcone synthase / Peroxisomal Thiolase; Chain A, domain 1 / Thiolase-like ...Chalcone/stilbene synthase, active site / Chalcone and stilbene synthases active site. / Chalcone/stilbene synthase, N-terminal / Polyketide synthase, type III / Chalcone/stilbene synthase, C-terminal / Chalcone and stilbene synthases, C-terminal domain / Chalcone and stilbene synthases, N-terminal domain / Thiolase/Chalcone synthase / Peroxisomal Thiolase; Chain A, domain 1 / Thiolase-like / 3-Layer(aba) Sandwich / Alpha BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_plant.gif) ![](data/taxo/icon/Arabidopsis_thaliana_S.png) Arabidopsis thaliana (thale cress) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 1.608 Å |
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Authors | Liou, G. / Chiang, Y.C. / Wang, Y. / Weng, J.K. |
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Funding support | United States, 1items Organization | Grant number | Country |
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National Science Foundation (NSF, United States) | CHE-1709616 | United States |
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Citation | Journal: J. Biol. Chem. / Year: 2018 Title: Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants. Authors: Liou, G. / Chiang, Y.C. / Wang, Y. / Weng, J.K. |
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History | Deposition | Jun 28, 2018 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Oct 17, 2018 | Provider: repository / Type: Initial release |
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Revision 1.1 | Dec 19, 2018 | Group: Data collection / Database references / Category: citation / citation_author Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation_author.identifier_ORCID |
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Revision 1.2 | Nov 27, 2019 | Group: Author supporting evidence / Category: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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Revision 2.0 | Nov 15, 2023 | Group: Atomic model / Data collection / Database references Category: atom_site / chem_comp_atom ...atom_site / chem_comp_atom / chem_comp_bond / database_2 Item: _atom_site.Cartn_x / _atom_site.Cartn_y ..._atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_atom_id / _atom_site.label_atom_id / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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