登録情報 | データベース: PDB / ID: 6bgh |
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タイトル | Solution NMR structure of Brd3 ET domain bound to Brg1 peptide |
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要素 | - Brd3_ET
- Bromodomain-containing protein 3
![](img/lk-wikipe.gif) |
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キーワード | TRANSCRIPTION (転写 (生物学)) / Transcription Bromodomain BET protein |
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機能・相同性 | 機能・相同性情報
positive regulation of glucose mediated signaling pathway / bBAF complex / npBAF complex / nBAF complex / positive regulation of transcription of nucleolar large rRNA by RNA polymerase I / negative regulation of androgen receptor signaling pathway / GBAF complex / neural retina development / regulation of G0 to G1 transition / Tat protein binding ...positive regulation of glucose mediated signaling pathway / bBAF complex / npBAF complex / nBAF complex / positive regulation of transcription of nucleolar large rRNA by RNA polymerase I / negative regulation of androgen receptor signaling pathway / GBAF complex / neural retina development / regulation of G0 to G1 transition / Tat protein binding / EGR2 and SOX10-mediated initiation of Schwann cell myelination / nucleosome disassembly / regulation of nucleotide-excision repair / RSC-type complex / RNA polymerase I preinitiation complex assembly / positive regulation by host of viral transcription / lncRNA binding / ATP-dependent chromatin remodeler activity / regulation of mitotic metaphase/anaphase transition / SWI/SNF complex / positive regulation of double-strand break repair / positive regulation of T cell differentiation / nuclear androgen receptor binding / positive regulation of stem cell population maintenance / RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known / endodermal cell differentiation / regulation of G1/S transition of mitotic cell cycle / negative regulation of cell differentiation / positive regulation of Wnt signaling pathway / positive regulation of myoblast differentiation / ATP-dependent activity, acting on DNA / Chromatin modifying enzymes / DNA polymerase binding / transcription initiation-coupled chromatin remodeling / protein localization to chromatin / Interleukin-7 signaling / helicase activity / molecular condensate scaffold activity / transcription coregulator binding / positive regulation of cell differentiation / Formation of the beta-catenin:TCF transactivating complex / 加水分解酵素; 酸無水物に作用; 酸無水物に作用・細胞または細胞小器官の運動に関与 / lysine-acetylated histone binding / negative regulation of cell growth / 動原体 / 核小体 / RMTs methylate histone arginines / positive regulation of DNA-binding transcription factor activity / nuclear matrix / positive regulation of miRNA transcription / transcription corepressor activity / p53 binding / nervous system development / positive regulation of cold-induced thermogenesis / chromatin organization / transcription coactivator activity / hydrolase activity / クロマチンリモデリング / negative regulation of DNA-templated transcription / chromatin binding / クロマチン / positive regulation of cell population proliferation / 核小体 / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / protein-containing complex / DNA binding / extracellular space / RNA binding / 核質 / ATP binding / 生体膜 / 細胞核類似検索 - 分子機能 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 - #220 / SWI/SNF complex subunit BRG1 / BRK domain / BRK domain / BRK domain superfamily / domain in transcription and CHROMO domain helicases / domain in helicases and associated with SANT domains / Glutamine-Leucine-Glutamine, QLQ / QLQ / QLQ domain profile. ...Substrate Binding Domain Of Dnak; Chain:A; Domain 2 - #220 / SWI/SNF complex subunit BRG1 / BRK domain / BRK domain / BRK domain superfamily / domain in transcription and CHROMO domain helicases / domain in helicases and associated with SANT domains / Glutamine-Leucine-Glutamine, QLQ / QLQ / QLQ domain profile. / QLQ / Snf2, ATP coupling domain / Snf2-ATP coupling, chromatin remodelling complex / Snf2-ATP coupling, chromatin remodelling complex / HSA domain / Helicase/SANT-associated domain / HSA domain profile. / : / SNF2-like, N-terminal domain superfamily / SNF2, N-terminal / SNF2-related domain / Substrate Binding Domain Of Dnak; Chain:A; Domain 2 / NET domain superfamily / NET domain profile. / Brdt, bromodomain, repeat II / Brdt, bromodomain, repeat I / NET domain / Bromodomain extra-terminal - transcription regulation / Helicase conserved C-terminal domain / Bromodomain, conserved site / Bromodomain signature. / ブロモドメイン / Bromodomain profile. / bromo domain / ブロモドメイン / Bromodomain-like superfamily / helicase superfamily c-terminal domain / Superfamilies 1 and 2 helicase C-terminal domain profile. / Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. / DEAD-like helicases superfamily / Helicase, C-terminal / Helicase superfamily 1/2, ATP-binding domain / Up-down Bundle / P-loop containing nucleoside triphosphate hydrolase / Mainly Alpha類似検索 - ドメイン・相同性 Transcription activator BRG1 / Bromodomain-containing protein 3類似検索 - 構成要素 |
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生物種 | ![](img/tx_human.gif) Homo sapiens (ヒト) |
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手法 | 溶液NMR / simulated annealing |
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データ登録者 | Szyszka, T.N. / Wai, D.C. / Mackay, J.P. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2018 タイトル: The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators. 著者: Wai, D.C.C. / Szyszka, T.N. / Campbell, A.E. / Kwong, C. / Wilkinson-White, L.E. / Silva, A.P.G. / Low, J.K.K. / Kwan, A.H. / Gamsjaeger, R. / Chalmers, J.D. / Patrick, W.M. / Lu, B. / Vakoc, ...著者: Wai, D.C.C. / Szyszka, T.N. / Campbell, A.E. / Kwong, C. / Wilkinson-White, L.E. / Silva, A.P.G. / Low, J.K.K. / Kwan, A.H. / Gamsjaeger, R. / Chalmers, J.D. / Patrick, W.M. / Lu, B. / Vakoc, C.R. / Blobel, G.A. / Mackay, J.P. |
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履歴 | 登録 | 2017年10月28日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2018年3月21日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2021年1月20日 | Group: Data collection / Database references カテゴリ: citation / citation_author / pdbx_nmr_spectrometer Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _pdbx_nmr_spectrometer.model |
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改定 1.2 | 2024年5月1日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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