登録情報 データベース : PDB / ID : 5heb 構造の表示 ダウンロードとリンクタイトル The third PDZ domain from the synaptic protein PSD-95 in complex with a C-terminal peptide derived from CRIPT 要素Cysteine-rich PDZ-binding protein Disks large homolog 4 詳細キーワード PEPTIDE BINDING PROTEIN / PDZ / GLGF (PDZドメイン) / DHR / adhesion (接着) / synapse (シナプス) / synaptic density / peptide-binding domain機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
regulation of postsynaptic density protein 95 clustering / RHO GTPases activate CIT / positive regulation of AMPA glutamate receptor clustering / neuronal ion channel clustering / P2Y1 nucleotide receptor binding / Neurexins and neuroligins / beta-1 adrenergic receptor binding / 胚 / neuroligin family protein binding / protein localization to microtubule ... regulation of postsynaptic density protein 95 clustering / RHO GTPases activate CIT / positive regulation of AMPA glutamate receptor clustering / neuronal ion channel clustering / P2Y1 nucleotide receptor binding / Neurexins and neuroligins / beta-1 adrenergic receptor binding / 胚 / neuroligin family protein binding / protein localization to microtubule / regulation of postsynaptic density assembly / structural constituent of postsynaptic density / proximal dendrite / positive regulation of neuron projection arborization / regulation of grooming behavior / synaptic vesicle maturation / receptor localization to synapse / cerebellar mossy fiber / cellular response to potassium ion / protein localization to synapse / vocalization behavior / LGI-ADAM interactions / neuron spine / Trafficking of AMPA receptors / 樹状突起 / Activation of Ca-permeable Kainate Receptor / AMPA glutamate receptor clustering / juxtaparanode region of axon / dendritic spine morphogenesis / negative regulation of receptor internalization / frizzled binding / neuron projection terminus / dendritic spine organization / postsynaptic neurotransmitter receptor diffusion trapping / acetylcholine receptor binding / establishment or maintenance of epithelial cell apical/basal polarity / positive regulation of synapse assembly / Synaptic adhesion-like molecules / RAF/MAP kinase cascade / neurotransmitter receptor localization to postsynaptic specialization membrane / positive regulation of dendrite morphogenesis / regulation of NMDA receptor activity / beta-2 adrenergic receptor binding / cortical cytoskeleton / regulation of neuronal synaptic plasticity / locomotory exploration behavior / social behavior / kinesin binding / positive regulation of excitatory postsynaptic potential / AMPA glutamate receptor complex / neuromuscular process controlling balance / excitatory synapse / positive regulation of protein tyrosine kinase activity / D1 dopamine receptor binding / Unblocking of NMDA receptors, glutamate binding and activation / glutamate receptor binding / postsynaptic density, intracellular component / positive regulation of synaptic transmission / cytoplasmic microtubule organization / extrinsic component of cytoplasmic side of plasma membrane / ionotropic glutamate receptor binding / dendrite cytoplasm / RNA splicing / dendritic shaft / synaptic membrane / cell periphery / PDZ domain binding / postsynaptic density membrane / regulation of long-term neuronal synaptic plasticity / spliceosomal complex / neuromuscular junction / establishment of protein localization / cerebral cortex development / 転写後修飾 / kinase binding / 細胞接着 / cell-cell junction / シナプス小胞 / 細胞結合 / positive regulation of cytosolic calcium ion concentration / scaffold protein binding / postsynapse / microtubule binding / chemical synaptic transmission / basolateral plasma membrane / postsynaptic membrane / protein phosphatase binding / protein-containing complex assembly / 樹状突起スパイン / postsynaptic density / neuron projection / signaling receptor binding / neuronal cell body / glutamatergic synapse / シナプス / 樹状突起 / protein-containing complex binding / protein kinase binding / 小胞体 / 生体膜 類似検索 - 分子機能 PDZ-binding protein, CRIPT / Microtubule-associated protein CRIPT / Polyubiquitination (PEST) N-terminal domain of MAGUK / Disks large homologue 1, N-terminal PEST domain / Polyubiquitination (PEST) N-terminal domain of MAGUK / PDZ-associated domain of NMDA receptors / PDZ-associated domain of NMDA receptors / Disks large 1-like / Guanylate kinase, conserved site / Guanylate kinase-like signature. ... PDZ-binding protein, CRIPT / Microtubule-associated protein CRIPT / Polyubiquitination (PEST) N-terminal domain of MAGUK / Disks large homologue 1, N-terminal PEST domain / Polyubiquitination (PEST) N-terminal domain of MAGUK / PDZ-associated domain of NMDA receptors / PDZ-associated domain of NMDA receptors / Disks large 1-like / Guanylate kinase, conserved site / Guanylate kinase-like signature. / Guanylate kinase-like domain profile. / Guanylate kinase-like domain / Guanylate kinase/L-type calcium channel beta subunit / Guanylate kinase / Guanylate kinase homologues. / PDZドメイン / Pdz3 Domain / PDZドメイン / SH3ドメイン / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZドメイン / PDZ superfamily / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3ドメイン / Roll / P-loop containing nucleoside triphosphate hydrolase / Mainly Beta 類似検索 - ドメイン・相同性 Disks large homolog 4 / Cysteine-rich PDZ-binding protein 類似検索 - 構成要素生物種 Rattus norvegicus (ドブネズミ)手法 X線回折 / 分子置換 / 解像度 : 1.65 Å 詳細データ登録者 White, K.I. / Raman, A.S. / Ranganathan, R. 資金援助 米国, 1件 詳細 詳細を隠す組織 認可番号 国 Robert A. Welch Foundation I-1366 米国
引用ジャーナル : Cell(Cambridge,Mass.) / 年 : 2016タイトル : Origins of Allostery and Evolvability in Proteins: A Case Study.著者 : Raman, A.S. / White, K.I. / Ranganathan, R. 履歴 登録 2016年1月5日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2016年11月16日 Provider : repository / タイプ : Initial release改定 1.1 2017年9月27日 Group : Author supporting evidence / Derived calculations / カテゴリ : pdbx_audit_support / pdbx_struct_oper_listItem : _pdbx_audit_support.funding_organization / _pdbx_struct_oper_list.symmetry_operation改定 1.2 2023年9月27日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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