cellular response to aluminum ion / オートファジー / : / phosphatidylinositol 3-kinase complex, class III / phosphatidylinositol 3-kinase complex, class III, type II / phosphatidylinositol 3-kinase complex, class III, type I / : / response to mitochondrial depolarisation / positive regulation of attachment of mitotic spindle microtubules to kinetochore / Ub-specific processing proteases ...cellular response to aluminum ion / オートファジー / : / phosphatidylinositol 3-kinase complex, class III / phosphatidylinositol 3-kinase complex, class III, type II / phosphatidylinositol 3-kinase complex, class III, type I / : / response to mitochondrial depolarisation / positive regulation of attachment of mitotic spindle microtubules to kinetochore / Ub-specific processing proteases / response to xenobiotic stimulus => GO:0009410 / negative regulation of lysosome organization / engulfment of apoptotic cell / positive regulation of autophagosome assembly / negative regulation of autophagosome assembly / receptor catabolic process / autophagy of mitochondrion / early endosome to late endosome transport / cellular response to nitrogen starvation / late endosome to vacuole transport / response to other organism / regulation of catalytic activity / phagophore assembly site / response to iron(II) ion / mitotic metaphase chromosome alignment / extrinsic component of membrane / lysosome organization / positive regulation of cardiac muscle hypertrophy / マイトファジー / autophagosome assembly / negative regulation of reactive oxygen species metabolic process / response to vitamin E / オートファゴソーム / neuron development / amyloid-beta metabolic process / cellular response to glucose starvation / phosphatidylinositol 3-kinase binding / positive regulation of autophagy / positive regulation of intrinsic apoptotic signaling pathway / phagocytic vesicle / cellular response to epidermal growth factor stimulus / cellular response to copper ion / cellular response to amino acid starvation / response to nutrient levels / negative regulation of autophagy / regulation of cytokinesis / ミトコンドリア / オートファジー / response to lead ion / ゴルジ体 / オートファジー / cellular response to hydrogen peroxide / GTPase binding / cytoplasmic vesicle / defense response to virus / endosome membrane / response to hypoxia / エンドソーム / negative regulation of cell population proliferation / 細胞分裂 / apoptotic process / ubiquitin protein ligase binding / 樹状突起 / endoplasmic reticulum membrane / negative regulation of apoptotic process / protein kinase binding / 小胞体 / protein-containing complex / identical protein binding / 細胞核 / 細胞質基質 / 細胞質 類似検索 - 分子機能
Beclin-1 / Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #3110 / Beclin-1, BH3 domain / Beclin-1 BH3 domain, Bcl-2-interacting / Atg6/Beclin / Atg6/Beclin C-terminal domain superfamily / Atg6, BARA domain / Atg6/beclin, coiled-coil domain / Apg6 BARA domain / Apg6 coiled-coil region ...Beclin-1 / Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #3110 / Beclin-1, BH3 domain / Beclin-1 BH3 domain, Bcl-2-interacting / Atg6/Beclin / Atg6/Beclin C-terminal domain superfamily / Atg6, BARA domain / Atg6/beclin, coiled-coil domain / Apg6 BARA domain / Apg6 coiled-coil region / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Helix non-globular / Special 類似検索 - ドメイン・相同性
構造決定の手法: 多重同系置換 / 解像度: 1.9→35.92 Å / Cor.coef. Fo:Fc: 0.941 / Cor.coef. Fo:Fc free: 0.933 / SU B: 2.666 / SU ML: 0.083 / 交差検証法: THROUGHOUT / ESU R Free: 0.142 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Rfactor
反射数
%反射
Selection details
Rfree
0.23631
1062
5.2 %
RANDOM
Rwork
0.20876
-
-
-
obs
0.21024
19438
100 %
-
溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: MASK