登録情報 | データベース: PDB / ID: 3pqr |
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タイトル | Crystal structure of Metarhodopsin II in complex with a C-terminal peptide derived from the Galpha subunit of transducin |
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要素 | - Guanine nucleotide-binding protein G(t) subunit alpha-1
- Rhodopsinロドプシン
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キーワード | SIGNALING PROTEIN / protein (タンパク質) / retinal protein (レチナール) / photoreceptor / active state / chromophore (発色団) / G-protein coupled receptor (Gタンパク質共役受容体) / glycoprotein (糖タンパク質) / lipoprotein (リポタンパク質) / palmitate (パルミチン酸) / phosphoprotein / photoreceptor protein / sensory transduction / transducer (トランスデューサー) / transmembrane (膜貫通型タンパク質) / vision / G-protein (Gタンパク質) / transducin / Galpha subunit / membrane (生体膜) / receptor (受容体) / GTP-binding / myristate (ミリスチン酸) / nucleotide-binding / G-protein-coupled receptor (Gタンパク質共役受容体) / rhodopsin (ロドプシン) / opsin |
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機能・相同性 | 機能・相同性情報
Opsins / VxPx cargo-targeting to cilium / rod bipolar cell differentiation / rod photoreceptor outer segment / sperm head plasma membrane / negative regulation of cyclic-nucleotide phosphodiesterase activity / podosome assembly / absorption of visible light / opsin binding / The canonical retinoid cycle in rods (twilight vision) ...Opsins / VxPx cargo-targeting to cilium / rod bipolar cell differentiation / rod photoreceptor outer segment / sperm head plasma membrane / negative regulation of cyclic-nucleotide phosphodiesterase activity / podosome assembly / absorption of visible light / opsin binding / The canonical retinoid cycle in rods (twilight vision) / : / G protein-coupled photoreceptor activity / photoreceptor inner segment membrane / G protein-coupled opsin signaling pathway / 11-cis retinal binding / cellular response to light stimulus / G protein-coupled receptor complex / Inactivation, recovery and regulation of the phototransduction cascade / phototransduction, visible light / thermotaxis / Activation of the phototransduction cascade / outer membrane / detection of temperature stimulus involved in thermoception / arrestin family protein binding / photoreceptor cell maintenance / acyl binding / photoreceptor outer segment membrane / G alpha (i) signalling events / phototransduction / response to light stimulus / photoreceptor outer segment / G-protein alpha-subunit binding / sperm midpiece / photoreceptor inner segment / 視覚 / guanyl-nucleotide exchange factor activity / G protein-coupled receptor binding / G-protein beta/gamma-subunit complex binding / adenylate cyclase-modulating G protein-coupled receptor signaling pathway / microtubule cytoskeleton organization / photoreceptor disc membrane / GDP binding / heterotrimeric G-protein complex / cell-cell junction / 遺伝子発現 / G protein-coupled receptor signaling pathway / ゴルジ体 / GTPase activity / GTP binding / protein kinase binding / zinc ion binding / 生体膜 / identical protein binding / metal ion binding / 細胞膜類似検索 - 分子機能 Rhodopsin, N-terminal / Amino terminal of the G-protein receptor rhodopsin / ロドプシン / Opsin / Visual pigments (opsins) retinal binding site / Visual pigments (opsins) retinal binding site. / Rhopdopsin 7-helix transmembrane proteins / Rhodopsin 7-helix transmembrane proteins / G-protein alpha subunit, group I / Serpentine type 7TM GPCR chemoreceptor Srsx ...Rhodopsin, N-terminal / Amino terminal of the G-protein receptor rhodopsin / ロドプシン / Opsin / Visual pigments (opsins) retinal binding site / Visual pigments (opsins) retinal binding site. / Rhopdopsin 7-helix transmembrane proteins / Rhodopsin 7-helix transmembrane proteins / G-protein alpha subunit, group I / Serpentine type 7TM GPCR chemoreceptor Srsx / G-alpha domain profile. / Guanine nucleotide binding protein (G-protein), alpha subunit / G protein alpha subunit, helical insertion / G-protein alpha subunit / G protein alpha subunit / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family) / Up-down Bundle / P-loop containing nucleoside triphosphate hydrolase / Mainly Alpha類似検索 - ドメイン・相同性 トレハロース / 酢酸塩 / パルミチン酸 / レチナール / ロドプシン / Guanine nucleotide-binding protein G(t) subunit alpha-1類似検索 - 構成要素 |
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生物種 | Bos taurus (ウシ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.85 Å |
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データ登録者 | Choe, H.-W. / Kim, Y.J. / Park, J.H. / Morizumi, T. / Pai, E.F. / Krauss, N. / Hofmann, K.P. / Scheerer, P. / Ernst, O.P. |
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引用 | ジャーナル: Nature / 年: 2011 タイトル: Crystal structure of metarhodopsin II. 著者: Choe, H.W. / Kim, Y.J. / Park, J.H. / Morizumi, T. / Pai, E.F. / Krauss, N. / Hofmann, K.P. / Scheerer, P. / Ernst, O.P. |
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履歴 | 登録 | 2010年11月26日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2011年3月9日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 2.0 | 2020年7月29日 | Group: Atomic model / Data collection ...Atomic model / Data collection / Database references / Derived calculations / Non-polymer description / Structure summary カテゴリ: atom_site / chem_comp ...atom_site / chem_comp / entity / entity_name_com / pdbx_branch_scheme / pdbx_chem_comp_identifier / pdbx_entity_branch / pdbx_entity_branch_descriptor / pdbx_entity_branch_link / pdbx_entity_branch_list / pdbx_entity_nonpoly / pdbx_molecule_features / pdbx_nonpoly_scheme / pdbx_struct_assembly_gen / struct_asym / struct_conn / struct_ref_seq_dif / struct_site / struct_site_gen Item: _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ..._atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_asym_id / _atom_site.auth_atom_id / _atom_site.auth_comp_id / _atom_site.auth_seq_id / _atom_site.label_asym_id / _atom_site.label_atom_id / _atom_site.label_comp_id / _atom_site.label_entity_id / _atom_site.type_symbol / _chem_comp.formula / _chem_comp.formula_weight / _chem_comp.id / _chem_comp.mon_nstd_flag / _chem_comp.name / _chem_comp.pdbx_synonyms / _chem_comp.type / _pdbx_struct_assembly_gen.asym_id_list / _struct_ref_seq_dif.details 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
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改定 2.1 | 2023年9月6日 | Group: Data collection / Database references ...Data collection / Database references / Refinement description / Structure summary カテゴリ: chem_comp / chem_comp_atom ...chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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