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- PDB-2zav: Arginase I (homo sapiens): native and unliganded structure at 1.7... -
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Open data
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Basic information
Entry | Database: PDB / ID: 2zav | ||||||
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Title | Arginase I (homo sapiens): native and unliganded structure at 1.70 A resolution | ||||||
![]() | Arginase-1![]() | ||||||
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Function / homology | ![]() positive regulation of neutrophil mediated killing of fungus / ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Di Costanzo, L. / Christianson, D.W. | ||||||
![]() | ![]() Title: Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster Authors: Di Costanzo, L. / Pique, M.E. / Christianson, D.W. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 138.2 KB | Display | ![]() |
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PDB format | ![]() | 106.6 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 2phaC ![]() 2phoC ![]() 2aebS C: citing same article ( S: Starting model for refinement |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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1 | ![]()
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2 | ![]()
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Unit cell |
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Components
#1: Protein | ![]() Mass: 34779.879 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() ![]() ![]() #2: Chemical | ChemComp-MN / #3: Water | ChemComp-HOH / | ![]() |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.36 Å3/Da / Density % sol: 47.87 % |
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Crystal grow![]() | Method: vapor diffusion, hanging drop / pH: 7 Details: 14% JEFFAMINE 2001, 0.1M HEPES pH 7.0, 50mM BICINE pH 8.5, 1.4mM Tymine, VAPOR DIFFUSION, HANGING DROP |
-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: ADSC QUANTUM 210 / Detector: CCD / Date: Feb 14, 2007 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength![]() |
Reflection twin | Type: merohedral / Operator: -h,-k,l / Fraction: 0.5 |
Reflection | Resolution: 1.7→50 Å / Num. all: 68183 / Num. obs: 68183 / % possible obs: 97.3 % / Observed criterion σ(F): 1 / Observed criterion σ(I): 2 / Redundancy: 4.4 % / Biso Wilson estimate: 22.6 Å2 / Rmerge(I) obs: 0.058 / Net I/σ(I): 3.5 |
Reflection shell | Resolution: 1.7→1.76 Å / Redundancy: 4.2 % / Rmerge(I) obs: 0.416 / Mean I/σ(I) obs: 3.52 / Num. unique all: 7000 / % possible all: 100 |
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Processing
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Refinement | Method to determine structure![]() ![]() Starting model: 2AEB: chain A Resolution: 1.7→50 Å / σ(I): 0 Details: Used weighted full matrix least squares procedure. the data diffraction is affect by perfect twinning, twin fraction: 0.5; operator: -h,-k,l The structure factor file is raw data file.
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Refinement step | Cycle: LAST / Resolution: 1.7→50 Å
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Refine LS restraints |
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