+Open data
-Basic information
Entry | Database: PDB / ID: 2rmg | ||||||
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Title | Human Urocortin 2 | ||||||
Components | Urocortin-2 | ||||||
Keywords | HORMONE / CRF ligand / Sauvagine / Astressin / Urocortins / Urotensins / CRF receptors / Secreted | ||||||
Function / homology | Function and homology information corticotropin-releasing hormone receptor binding / corticotropin-releasing hormone receptor 2 binding / hormone binding / Class B/2 (Secretin family receptors) / cellular response to nutrient levels / digestion / hormone-mediated signaling pathway / adenylate cyclase-activating G protein-coupled receptor signaling pathway / hormone activity / extracellular space / extracellular region Similarity search - Function | ||||||
Method | SOLUTION NMR / torsion angle dynamics | ||||||
Authors | Grace, C.R.R. / Perrin, M.H. / Cantle, J.P. / Vale, W.W. / Rivier, J.E. / Riek, R. | ||||||
Citation | Journal: J.Am.Chem.Soc. / Year: 2007 Title: Common and divergent structural features of a series of corticotropin releasing factor-related peptides Authors: Grace, C.R.R. / Perrin, M.H. / Cantle, J.P. / Vale, W.W. / Rivier, J.E. / Riek, R. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2rmg.cif.gz | 241.4 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2rmg.ent.gz | 199.2 KB | Display | PDB format |
PDBx/mmJSON format | 2rmg.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/rm/2rmg ftp://data.pdbj.org/pub/pdb/validation_reports/rm/2rmg | HTTPS FTP |
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-Related structure data
-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 4158.913 Da / Num. of mol.: 1 / Source method: obtained synthetically / Details: Solid-phase approach / References: UniProt: Q96RP3 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||
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NMR experiment |
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-Sample preparation
Details | Contents: 1.5mM Human Ucn2, DMSO / Solvent system: DMSO |
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Sample | Conc.: 1.5 mM / Component: Human Ucn2 |
Sample conditions | Pressure: ambient / Temperature: 298 K |
-NMR measurement
NMR spectrometer | Type: Bruker INOVA / Manufacturer: Bruker / Model: INOVA / Field strength: 700 MHz |
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-Processing
NMR software |
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Refinement | Method: torsion angle dynamics / Software ordinal: 1 | ||||||||||||
NMR representative | Selection criteria: lowest energy | ||||||||||||
NMR ensemble | Conformer selection criteria: target function / Conformers calculated total number: 100 / Conformers submitted total number: 20 |