Entry Database : PDB / ID : 2miq Structure visualization Downloads & linksTitle Solution NMR Structure of PHD Type 1 Zinc Finger Domain 1 of Lysine-specific Demethylase Lid from Drosophila melanogaster, Northeast Structural Genomics Consortium (NESG) Target FR824J ComponentsLysine-specific demethylase lid Details Keywords OXIDOREDUCTASE / Zinc finger / PSI-Biology / Structural Genomics / Northeast Structural Genomics Consortium / NESG / Chaperone-Enabled Studies of Epigenetic Regulation Enzymes / CEBSFunction / homology Function and homology informationFunction Domain/homology Component
TFAP2 (AP-2) family regulates transcription of cell cycle factors / histone H4R3 demethylase activity / male germ-line stem cell population maintenance / synaptonemal complex organization / oocyte karyosome formation / larval somatic muscle development / [histone H3]-trimethyl-L-lysine4 demethylase / histone H3K4me/H3K4me2/H3K4me3 demethylase activity / negative regulation of stem cell differentiation / enzyme inhibitor activity ... TFAP2 (AP-2) family regulates transcription of cell cycle factors / histone H4R3 demethylase activity / male germ-line stem cell population maintenance / synaptonemal complex organization / oocyte karyosome formation / larval somatic muscle development / [histone H3]-trimethyl-L-lysine4 demethylase / histone H3K4me/H3K4me2/H3K4me3 demethylase activity / negative regulation of stem cell differentiation / enzyme inhibitor activity / Sin3-type complex / locomotor rhythm / histone reader activity / circadian regulation of gene expression / chromatin organization / chromatin remodeling / chromatin / regulation of DNA-templated transcription / positive regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / DNA binding / metal ion binding / nucleus Similarity search - Function : / : / Lysine-specific demethylase 5, C-terminal helical domain / Lysine-specific demethylase-like domain / PLU-1-like protein / Zinc finger, C5HC2-type / C5HC2 zinc finger / ARID/BRIGHT DNA binding domain / ARID DNA-binding domain / ARID DNA-binding domain superfamily ... : / : / Lysine-specific demethylase 5, C-terminal helical domain / Lysine-specific demethylase-like domain / PLU-1-like protein / Zinc finger, C5HC2-type / C5HC2 zinc finger / ARID/BRIGHT DNA binding domain / ARID DNA-binding domain / ARID DNA-binding domain superfamily / ARID/BRIGHT DNA binding domain / ARID domain profile. / BRIGHT, ARID (A/T-rich interaction domain) domain / JmjN domain / jmjN domain / JmjN domain profile. / Small domain found in the jumonji family of transcription factors / Zinc/RING finger domain, C3HC4 (zinc finger) / Herpes Virus-1 / JmjC domain, hydroxylase / A domain family that is part of the cupin metalloenzyme superfamily. / JmjC domain / JmjC domain profile. / Zinc finger, PHD-type, conserved site / PHD-finger / Zinc finger PHD-type signature. / Zinc finger PHD-type profile. / Zinc finger, PHD-finger / Zinc finger, PHD-type / PHD zinc finger / Zinc finger, FYVE/PHD-type / Zinc finger, RING/FYVE/PHD-type / 2-Layer Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species Drosophila melanogaster (fruit fly)Method SOLUTION NMR / simulated annealing DetailsModel details lowest energy, model1 Authors Xu, X. / Eletsky, A. / Shastry, R. / Maglaqui, M. / Janjua, H. / Xiao, R. / Everett, J.K. / Sukumaran, D.K. / Montelione, G.T. / Szyperski, T. ...Xu, X. / Eletsky, A. / Shastry, R. / Maglaqui, M. / Janjua, H. / Xiao, R. / Everett, J.K. / Sukumaran, D.K. / Montelione, G.T. / Szyperski, T. / Northeast Structural Genomics Consortium (NESG) / Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS) CitationJournal : To be Published Title : Solution NMR Structure of PHD Type 1 Zinc Finger Domain 1 from Lysine-specific Demethylase Lid from Drosophila melanogaster, Northeast Structural Genomics Consortium (NESG) Target FR824JAuthors : Xu, X. / Eletsky, A. / Shastry, R. / Maglaqui, M. / Janjua, H. / Xiao, R. / Everett, J.K. / Sukumaran, D. / Montelione, G.T. / Szyperski, T. History Deposition Dec 17, 2013 Deposition site : BMRB / Processing site : RCSBRevision 1.0 Jan 29, 2014 Provider : repository / Type : Initial releaseRevision 1.1 Feb 19, 2014 Group : Structure summaryRevision 1.2 Apr 23, 2014 Group : Database references / Structure summaryRevision 1.3 Jun 14, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other Category : database_2 / pdbx_database_status ... database_2 / pdbx_database_status / pdbx_nmr_software / pdbx_struct_conn_angle / struct_conn / struct_ref_seq_dif / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data / _pdbx_nmr_software.name / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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