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Yorodumi- PDB-2m0c: Solution NMR Structure of Homeobox Domain of Human ALX4, Northeas... -
+Open data
-Basic information
Entry | Database: PDB / ID: 2m0c | ||||||
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Title | Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C | ||||||
Components | Homeobox protein aristaless-like 4 | ||||||
Keywords | GENE REGULATION / Structural Genomics / NORTHEAST STRUCTURAL GENOMICS CONSORTIUM / NESG / PSI-Biology / Protein Structure Initiative | ||||||
Function / homology | Function and homology information HMG box domain binding / embryonic skeletal system morphogenesis / digestive tract development / embryonic forelimb morphogenesis / embryonic hindlimb morphogenesis / muscle organ development / anterior/posterior pattern specification / embryonic digit morphogenesis / roof of mouth development / hair follicle development ...HMG box domain binding / embryonic skeletal system morphogenesis / digestive tract development / embryonic forelimb morphogenesis / embryonic hindlimb morphogenesis / muscle organ development / anterior/posterior pattern specification / embryonic digit morphogenesis / roof of mouth development / hair follicle development / post-embryonic development / skeletal system development / RNA polymerase II transcription regulatory region sequence-specific DNA binding / sequence-specific double-stranded DNA binding / DNA-binding transcription activator activity, RNA polymerase II-specific / regulation of apoptotic process / transcription regulator complex / DNA-binding transcription factor activity, RNA polymerase II-specific / chromatin / regulation of transcription by RNA polymerase II / DNA binding / nucleoplasm / nucleus Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | SOLUTION NMR / simulated annealing | ||||||
Model details | lowest energy, model 1 | ||||||
Authors | Xu, X. / Eletsky, A. / Pulavarti, S. / Lee, D. / Janjua, H. / Xiao, R. / Acton, T.B. / Everett, J.K. / Montelione, G.T. / Szyperski, T. / Northeast Structural Genomics Consortium (NESG) | ||||||
Citation | Journal: To be Published Title: Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C Authors: Xu, X. / Eletsky, A. / Pulavarti, S. / Lee, D. / Janjua, H. / Xiao, R. / Acton, T.B. / Everett, J.K. / Montelione, G.T. / Szyperski, T. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2m0c.cif.gz | 587.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2m0c.ent.gz | 501.6 KB | Display | PDB format |
PDBx/mmJSON format | 2m0c.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/m0/2m0c ftp://data.pdbj.org/pub/pdb/validation_reports/m0/2m0c | HTTPS FTP |
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-Related structure data
Similar structure data | |
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Other databases |
-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 9356.658 Da / Num. of mol.: 1 / Fragment: Homeobox DNA binding residues 209-280 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Gene: ALX4, KIAA1788 / Production host: Escherichia coli (E. coli) / Strain (production host): BL21(DE3)pMgK / References: UniProt: Q9H161 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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NMR experiment |
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-Sample preparation
Details |
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Sample |
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Sample conditions | pH: 7.5 / Pressure: ambient / Temperature: 298 K |
-NMR measurement
NMR spectrometer |
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-Processing
NMR software |
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