activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c / Release of apoptotic factors from the mitochondria / CD40 receptor complex / SMAC, XIAP-regulated apoptotic response / Regulation of the apoptosome activity / SMAC (DIABLO) binds to IAPs / SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes / intrinsic apoptotic signaling pathway in response to oxidative stress / cysteine-type endopeptidase inhibitor activity involved in apoptotic process / extrinsic apoptotic signaling pathway via death domain receptors ...activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c / Release of apoptotic factors from the mitochondria / CD40 receptor complex / SMAC, XIAP-regulated apoptotic response / Regulation of the apoptosome activity / SMAC (DIABLO) binds to IAPs / SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes / intrinsic apoptotic signaling pathway in response to oxidative stress / cysteine-type endopeptidase inhibitor activity involved in apoptotic process / extrinsic apoptotic signaling pathway via death domain receptors / intrinsic apoptotic signaling pathway / positive regulation of protein ubiquitination / ミトコンドリア / cytoplasmic side of plasma membrane / activation of cysteine-type endopeptidase activity involved in apoptotic process / ubiquitin protein ligase activity / positive regulation of canonical Wnt signaling pathway / neuron apoptotic process / regulation of cell cycle / positive regulation of apoptotic process / apoptotic process / negative regulation of apoptotic process / ミトコンドリア / metal ion binding / 細胞核 / 細胞質基質 / 細胞質 類似検索 - 分子機能
Smac/DIABLO-like superfamily / Smac/DIABLO protein / Second Mitochondria-derived Activator of Caspases / XIAP/BIRC8, UBA domain / : / BIRC2/3-like, UBA domain / Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A / Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A / BIR repeat. / BIR repeat ...Smac/DIABLO-like superfamily / Smac/DIABLO protein / Second Mitochondria-derived Activator of Caspases / XIAP/BIRC8, UBA domain / : / BIRC2/3-like, UBA domain / Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A / Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A / BIR repeat. / BIR repeat / Inhibitor of Apoptosis domain / BIR repeat profile. / Baculoviral inhibition of apoptosis protein repeat / Zinc finger, C3HC4 type (RING finger) / Death-like domain superfamily / 薬指 / Zinc finger RING-type profile. / Zinc finger, RING-type / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性
Baculoviral IAP repeat-containing protein 8 / Diablo IAP-binding mitochondrial protein 類似検索 - 構成要素
BaculoviralIAPrepeat-containingprotein8 / Inhibitor of apoptosis-like protein 2 / IAP-like protein 2 / ILP-2 / Testis-specific inhibitor of ...Inhibitor of apoptosis-like protein 2 / IAP-like protein 2 / ILP-2 / Testis-specific inhibitor of apoptosis / XILP2
分子量: 12349.910 Da / 分子数: 6 / 由来タイプ: 組換発現 詳細: XILP2: human ILP2 with an N-terminal fusion (residues 253-261 from human XIAP) 由来: (組換発現) Homo sapiens (ヒト) / 遺伝子: BIRC8, ILP2 / プラスミド: pet15b / 生物種 (発現宿主): Escherichia coli / 発現宿主: Escherichia coli BL21(DE3) (大腸菌) / 株 (発現宿主): BL21DE3 / 参照: UniProt: Q96P09
#2: タンパク質・ペプチド
Diablohomolog, mitochondrial / / Second mitochondria-derived activator of caspase / Smac protein / Direct IAP binding protein with low pI
分子量: 726.883 Da / 分子数: 6 / 由来タイプ: 合成 詳細: The peptide was chemically synthesized. The sequence of the peptide is naturally found in Homo sapiens (human). 参照: UniProt: Q9NR28