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Open data
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Basic information
Entry | Database: PDB / ID: 1qr2 | ||||||
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Title | HUMAN QUINONE REDUCTASE TYPE 2 | ||||||
![]() | PROTEIN (QUINONE REDUCTASE TYPE 2) | ||||||
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Function / homology | ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() | ||||||
![]() | Foster, C. / Bianchet, M.A. / Talalay, P. / Amzel, L.M. | ||||||
![]() | ![]() Title: Crystal structure of human quinone reductase type 2, a metalloflavoprotein. Authors: Foster, C.E. / Bianchet, M.A. / Talalay, P. / Zhao, Q. / Amzel, L.M. #1: Journal: Proc.Natl.Acad.Sci.USA / Year: 1997 Title: Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase) Authors: Zhao, Q. / Yang, X.L. / Holtzclaw, W.D. / Talalay, P. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 133.5 KB | Display | ![]() |
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PDB format | ![]() | 103.9 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 2qr2C ![]() 1qrdS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS oper: (Code: given Matrix: (0.761451, -0.007801, -0.648175), Vector ![]() |
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Components
#1: Protein | Mass: 25849.338 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() ![]() #2: Chemical | #3: Chemical | ![]() #4: Water | ChemComp-HOH / | ![]() Sequence details | THE SEQUENCE DATABASE IS IN ERROR AT RESIDUE 140, CYS. THE CORRECT RESIDUE IS GLY. (RESIDUE 139 IN ...THE SEQUENCE DATABASE IS IN ERROR AT RESIDUE 140, CYS. THE CORRECT RESIDUE IS GLY. (RESIDUE 139 IN THE COORDINATE | |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.4 Å3/Da / Density % sol: 49 % | ||||||||||||||||||||||||||||||
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Crystal grow![]() | pH: 7 / Details: pH 7.0 | ||||||||||||||||||||||||||||||
Crystal | *PLUS | ||||||||||||||||||||||||||||||
Crystal grow | *PLUS Temperature: 18 ℃ / Method: vapor diffusion, hanging drop | ||||||||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Diffraction | Mean temperature: 93 K |
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Diffraction source | Source: ![]() |
Detector | Type: RIGAKU RAXIS IV / Detector: IMAGE PLATE / Date: Jan 1, 1997 |
Radiation | Monochromator: GRAPHITE / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength![]() |
Reflection | Resolution: 2.1→100 Å / Num. obs: 27290 / % possible obs: 89.8 % / Redundancy: 6.3 % / Rsym value: 5.7 / Net I/σ(I): 25 |
Reflection shell | Resolution: 2.1→2.2 Å / Redundancy: 2.6 % / Mean I/σ(I) obs: 4 / Rsym value: 24.4 / % possible all: 75.7 |
Reflection | *PLUS Num. measured all: 171959 / Rmerge(I) obs: 0.057 |
Reflection shell | *PLUS % possible obs: 75.7 % / Rmerge(I) obs: 0.244 |
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Processing
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Refinement | Method to determine structure![]() ![]() Starting model: PDB ENTRY 1QRD Resolution: 2.1→6 Å / Data cutoff high absF: 1000000 / Data cutoff low absF: 0.001 / Cross valid method: THROUGHOUT / σ(F): 3
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Refine analyze | Luzzati d res low obs: 6 Å | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 2.1→6 Å
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Refine LS restraints |
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Refine LS restraints NCS | NCS model details: RESTRAINTS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
LS refinement shell | Resolution: 2.1→2.15 Å / Total num. of bins used: 15
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Xplor file |
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Software | *PLUS Name: ![]() | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement | *PLUS Lowest resolution: 6 Å / σ(F): 3 / % reflection Rfree: 10 % / Rfactor obs: 0.219 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS
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LS refinement shell | *PLUS Rfactor Rfree: 0.329 / % reflection Rfree: 10 % / Rfactor Rwork: 0.299 |