登録情報 データベース : PDB / ID : 1khc 構造の表示 ダウンロードとリンクタイトル Crystal Structure of the PWWP Domain of Mammalian DNA Methyltransferase Dnmt3b 要素DNA cytosine-5 methyltransferase 3B2 詳細 キーワード TRANSFERASE (転移酵素) / Five beta-sheets barrel followed by Five-helix bundle機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
: / DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates / : / heterochromatin => GO:0000792 / : / SUMOylation of DNA methylation proteins / : / PRC2 methylates histones and DNA / DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates / epigenetic programming of gene expression ... : / DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates / : / heterochromatin => GO:0000792 / : / SUMOylation of DNA methylation proteins / : / PRC2 methylates histones and DNA / DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates / epigenetic programming of gene expression / : / DNAメチルトランスフェラーゼ / DNA (cytosine-5-)-methyltransferase activity / : / DNA methylation-dependent heterochromatin formation / protein-containing complex localization / negative regulation of gene expression, epigenetic / chromosome, centromeric region / ヘテロクロマチン / positive regulation of neuron differentiation / methyltransferase activity / cellular response to amino acid stimulus / histone deacetylase binding / transcription corepressor activity / negative regulation of DNA-templated transcription / chromatin binding / positive regulation of gene expression / negative regulation of transcription by RNA polymerase II / DNA binding / 核質 / metal ion binding / 細胞核 / 細胞質 類似検索 - 分子機能 PWWP, helical domain / DNA (cytosine-5)-methyltransferase 3B, ADD domain / Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 / DNMT3, cysteine rich ADD domain / DNMT3, cysteine rich ADD domain, GATA1-like zinc finger / ADD domain / ADD domain profile. / DNA methylase, C-5 cytosine-specific, active site / C-5 cytosine-specific DNA methylases active site. / C-5 cytosine-specific DNA methylase (Dnmt) domain profile. ... PWWP, helical domain / DNA (cytosine-5)-methyltransferase 3B, ADD domain / Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 / DNMT3, cysteine rich ADD domain / DNMT3, cysteine rich ADD domain, GATA1-like zinc finger / ADD domain / ADD domain profile. / DNA methylase, C-5 cytosine-specific, active site / C-5 cytosine-specific DNA methylases active site. / C-5 cytosine-specific DNA methylase (Dnmt) domain profile. / C-5 cytosine methyltransferase / C-5 cytosine-specific DNA methylase / SH3 type barrels. - #140 / domain with conserved PWWP motif / PWWP domain / PWWP domain profile. / PWWP domain / Zinc finger, FYVE/PHD-type / SH3 type barrels. / Roll / S-adenosyl-L-methionine-dependent methyltransferase superfamily / Orthogonal Bundle / Mainly Beta / Mainly Alpha 類似検索 - ドメイン・相同性生物種 Mus musculus (ハツカネズミ)手法 X線回折 / 多波長異常分散 / 解像度 : 1.8 Å 詳細データ登録者 Qiu, C. / Sawada, K. / Zhang, X. / Cheng, X. 引用ジャーナル : Nat.Struct.Biol. / 年 : 2002タイトル : The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.著者 : Qiu, C. / Sawada, K. / Zhang, X. / Cheng, X. 履歴 登録 2001年11月29日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2002年2月27日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月27日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2011年11月16日 Group : Atomic model改定 1.4 2024年2月14日 Group : Data collection / Database references / Derived calculationsカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / struct_conn / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
すべて表示 表示を減らす Remark 600 HETEROGEN THE AUTHORS WERE UNABLE TO FIGURE OUT THE IDENTITY OF THE MOLECULES LABELED AS "UNX" FROM ... HETEROGEN THE AUTHORS WERE UNABLE TO FIGURE OUT THE IDENTITY OF THE MOLECULES LABELED AS "UNX" FROM THE ELECTRON DENSITY.