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Yorodumi- PDB-1cfi: NMR STRUCTURE OF CALCIUM ION-BOUND GAMMA-CARBOXY-GLUTAMIC ACID-RI... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1cfi | ||||||
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Title | NMR STRUCTURE OF CALCIUM ION-BOUND GAMMA-CARBOXY-GLUTAMIC ACID-RICH DOMAIN OF FACTOR IX | ||||||
Components | COAGULATION FACTOR IXFactor IX | ||||||
Keywords | COAGULATION FACTOR / BLOOD COAGULATION / PLASMA / SERINE PROTEASE / CALCIUM-BINDING | ||||||
Function / homology | Function and homology information Defective F9 secretion / Defective gamma-carboxylation of F9 / coagulation factor IXa / Defective F9 activation / Defective factor IX causes thrombophilia / Defective cofactor function of FVIIIa variant / Defective F9 variant does not activate FX / zymogen activation / Extrinsic Pathway of Fibrin Clot Formation / Protein hydroxylation ...Defective F9 secretion / Defective gamma-carboxylation of F9 / coagulation factor IXa / Defective F9 activation / Defective factor IX causes thrombophilia / Defective cofactor function of FVIIIa variant / Defective F9 variant does not activate FX / zymogen activation / Extrinsic Pathway of Fibrin Clot Formation / Protein hydroxylation / Gamma-carboxylation of protein precursors / Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus / Removal of aminoterminal propeptides from gamma-carboxylated proteins / Intrinsic Pathway of Fibrin Clot Formation / Golgi lumen / blood coagulation / collagen-containing extracellular matrix / endopeptidase activity / endoplasmic reticulum lumen / serine-type endopeptidase activity / calcium ion binding / proteolysis / extracellular space / extracellular exosome / extracellular region / metal ion binding / plasma membrane Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Freedman, S.J. / Furie, B.C. / Furie, B. / Baleja, J.D. | ||||||
Citation | Journal: Biochemistry / Year: 1995 Title: Structure of the calcium ion-bound gamma-carboxyglutamic acid-rich domain of factor IX. Authors: Freedman, S.J. / Furie, B.C. / Furie, B. / Baleja, J.D. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1cfi.cif.gz | 151.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1cfi.ent.gz | 129.7 KB | Display | PDB format |
PDBx/mmJSON format | 1cfi.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/cf/1cfi ftp://data.pdbj.org/pub/pdb/validation_reports/cf/1cfi | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 6293.366 Da / Num. of mol.: 1 Fragment: THE GLA AND AROMATIC AMINO ACID STACK DOMAINS, RESIDUES 1 - 47 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Organ: BLOOD / References: UniProt: P00740, coagulation factor IXa |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Sample conditions | pH: 5.35 / Temperature units: K |
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Crystal grow | *PLUS Method: other / Details: NMR |
-Processing
NMR software | Name: DGII / Developer: HAVEL / Classification: refinement |
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NMR ensemble | Conformers submitted total number: 17 |