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Open data
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Basic information
Entry | Database: PDB / ID: 1bn1 | ||||||
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Title | CARBONIC ANHYDRASE II INHIBITOR | ||||||
![]() | CARBONIC ANHYDRASE![]() | ||||||
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Function / homology | ![]() positive regulation of cellular pH reduction / positive regulation of dipeptide transmembrane transport / regulation of monoatomic anion transport / ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() | ||||||
![]() | Boriack-Sjodin, P.A. / Zeitlin, S. / Christianson, D.W. | ||||||
![]() | ![]() Title: Structural analysis of inhibitor binding to human carbonic anhydrase II. Authors: Boriack-Sjodin, P.A. / Zeitlin, S. / Chen, H.H. / Crenshaw, L. / Gross, S. / Dantanarayana, A. / Delgado, P. / May, J.A. / Dean, T. / Christianson, D.W. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 77 KB | Display | ![]() |
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PDB format | ![]() | 56.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 1bn3C ![]() 1bn4C ![]() 1bnmC ![]() 1bnnC ![]() 1bnqC ![]() 1bntC ![]() 1bnuC ![]() 1bnvC ![]() 1bnwC ![]() 2cbaS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
#1: Protein | ![]() Mass: 29157.863 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) ![]() ![]() ![]() ![]() |
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#2: Chemical | ChemComp-HG / ![]() |
#3: Chemical | ChemComp-ZN / |
#4: Chemical | ChemComp-AL5 / |
#5: Water | ChemComp-HOH / ![]() |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.17 Å3/Da / Density % sol: 43 % | |||||||||||||||||||||||||
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Crystal grow![]() | pH: 10 / Details: pH 10.0 | |||||||||||||||||||||||||
Crystal | *PLUS | |||||||||||||||||||||||||
Crystal grow | *PLUS pH: 8 / Method: vapor diffusion, sitting drop | |||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Diffraction | Mean temperature: 298 K |
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Diffraction source | Source: ![]() |
Detector | Type: RIGAKU RAXIS / Detector: IMAGE PLATE / Date: Jun 1, 1994 / Details: MIRRORS |
Radiation | Monochromator: NI FILTER / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength![]() |
Reflection | Resolution: 2.1→6.5 Å / Num. obs: 13725 / % possible obs: 93.1 % / Observed criterion σ(I): 2 / Redundancy: 3.5 % / Rmerge(I) obs: 0.063 |
Reflection | *PLUS Num. measured all: 51323 |
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Processing
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Refinement | Method to determine structure![]() Starting model: PDB ENTRY 2CBA Resolution: 2.1→6.5 Å / Data cutoff high absF: 100000 / Data cutoff low absF: 0.1 / σ(F): 2
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Refinement step | Cycle: LAST / Resolution: 2.1→6.5 Å
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Refine LS restraints |
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Xplor file |
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Software | *PLUS Name: ![]() | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS
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