+Open data
-Basic information
Entry | Database: PDB / ID: 1ar8 | |||||||||
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Title | P1/MAHONEY POLIOVIRUS, MUTANT P1095S | |||||||||
Components | (P1/MAHONEY POLIOVIRUS) x 5 | |||||||||
Keywords | VIRUS / PICORNAVIRUS / POLIOVIRUS / COAT PROTEIN / Icosahedral virus | |||||||||
Function / homology | Function and homology information symbiont-mediated suppression of host translation initiation / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity / picornain 2A / symbiont-mediated suppression of host mRNA export from nucleus / ribonucleoside triphosphate phosphatase activity / symbiont genome entry into host cell via pore formation in plasma membrane / picornain 3C / T=pseudo3 icosahedral viral capsid ...symbiont-mediated suppression of host translation initiation / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity / picornain 2A / symbiont-mediated suppression of host mRNA export from nucleus / ribonucleoside triphosphate phosphatase activity / symbiont genome entry into host cell via pore formation in plasma membrane / picornain 3C / T=pseudo3 icosahedral viral capsid / host cell cytoplasmic vesicle membrane / endocytosis involved in viral entry into host cell / nucleoside-triphosphate phosphatase / protein complex oligomerization / monoatomic ion channel activity / RNA helicase activity / induction by virus of host autophagy / cysteine-type endopeptidase activity / RNA-directed RNA polymerase / viral RNA genome replication / virus-mediated perturbation of host defense response / RNA-dependent RNA polymerase activity / DNA-templated transcription / host cell nucleus / virion attachment to host cell / structural molecule activity / proteolysis / RNA binding / ATP binding / membrane / metal ion binding Similarity search - Function | |||||||||
Biological species | Human poliovirus 1 | |||||||||
Method | X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution: 2.9 Å | |||||||||
Authors | Wien, M.W. / Curry, S. / Filman, D.J. / Hogle, J.M. | |||||||||
Citation | Journal: Nat.Struct.Biol. / Year: 1997 Title: Structural studies of poliovirus mutants that overcome receptor defects. Authors: Wien, M.W. / Curry, S. / Filman, D.J. / Hogle, J.M. #1: Journal: Acta Crystallogr.,Sect.D / Year: 1996 Title: A Pseudo-Cell Based Approach to Efficient Crystallographic Refinement of Viruses Authors: Jacobson, D.H. / Hogle, J.M. / Filman, D.J. #2: Journal: J.Virol. / Year: 1995 Title: Poliovirus Variants Selected on Mutant Receptor-Expressing Cells Identify Capsid Residues that Expand Receptor Recognition Authors: Colston, E.M. / Racaniello, V.R. #3: Journal: Science / Year: 1985 Title: Three-Dimensional Structure of Poliovirus at 2.9 A Resolution Authors: Hogle, J.M. / Chow, M. / Filman, D.J. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1ar8.cif.gz | 170.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1ar8.ent.gz | 131.5 KB | Display | PDB format |
PDBx/mmJSON format | 1ar8.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1ar8_validation.pdf.gz | 446.2 KB | Display | wwPDB validaton report |
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Full document | 1ar8_full_validation.pdf.gz | 461.3 KB | Display | |
Data in XML | 1ar8_validation.xml.gz | 19.3 KB | Display | |
Data in CIF | 1ar8_validation.cif.gz | 32.2 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ar/1ar8 ftp://data.pdbj.org/pub/pdb/validation_reports/ar/1ar8 | HTTPS FTP |
-Related structure data
Related structure data | 1al2C 1ar6C 1ar7C 1ar9C 1asjC 2plvS S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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4 |
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5 |
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Unit cell |
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Symmetry | Point symmetry: (Hermann–Mauguin notation: 532 / Schoenflies symbol: I (icosahedral)) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Noncrystallographic symmetry (NCS) | NCS oper:
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