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Open data
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Basic information
Entry | ![]() | |||||||||
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Title | VMAT2 protonated state | |||||||||
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![]() | transporter B / ![]() | |||||||||
Function / homology | ![]() serotonin secretion by mast cell / sequestering of neurotransmitter / somato-dendritic dopamine secretion / histamine uptake / neurotransmitter loading into synaptic vesicle / monoamine:proton antiporter activity / aminergic neurotransmitter loading into synaptic vesicle / clathrin-sculpted monoamine transport vesicle membrane / Serotonin Neurotransmitter Release Cycle / serotonin:sodium:chloride symporter activity ...serotonin secretion by mast cell / sequestering of neurotransmitter / somato-dendritic dopamine secretion / histamine uptake / neurotransmitter loading into synaptic vesicle / monoamine:proton antiporter activity / aminergic neurotransmitter loading into synaptic vesicle / clathrin-sculpted monoamine transport vesicle membrane / Serotonin Neurotransmitter Release Cycle / serotonin:sodium:chloride symporter activity / Dopamine Neurotransmitter Release Cycle / Norepinephrine Neurotransmitter Release Cycle / serotonin uptake / dopaminergic synapse / dopamine transport / monoamine transmembrane transporter activity / Na+/Cl- dependent neurotransmitter transporters / monoamine transport / histamine secretion by mast cell / ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Similarity search - Function | |||||||||
Biological species | ![]() ![]() | |||||||||
Method | ![]() ![]() | |||||||||
![]() | Jiang DH / Wu D | |||||||||
Funding support | ![]()
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![]() | ![]() Title: VMAT2 protonated state Authors: Jiang DH / Wu D | |||||||||
History |
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Structure visualization
Supplemental images |
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Downloads & links
-EMDB archive
Map data | ![]() | 117.8 MB | ![]() | |
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Header (meta data) | ![]() ![]() | 12.4 KB 12.4 KB | Display Display | ![]() |
Images | ![]() | 28.2 KB | ||
Filedesc metadata | ![]() | 5.2 KB | ||
Others | ![]() ![]() | 116 MB 116 MB | ||
Archive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 8xobMC M: atomic model generated by this map C: citing same article ( |
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Similar structure data | Similarity search - Function & homology ![]() |
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Links
EMDB pages | ![]() ![]() |
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Related items in Molecule of the Month |
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Map
File | ![]() | ||||||||||||||||||||
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Voxel size | X=Y=Z: 0.85 Å | ||||||||||||||||||||
Density |
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Symmetry | Space group: 1 | ||||||||||||||||||||
Details | EMDB XML:
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-Supplemental data
-Half map: #2
File | emd_38525_half_map_1.map | ||||||||||||
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Projections & Slices |
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Density Histograms |
-Half map: #1
File | emd_38525_half_map_2.map | ||||||||||||
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Projections & Slices |
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Density Histograms |
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Sample components
-Entire : complex with p
Entire | Name: complex with p |
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Components |
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-Supramolecule #1: complex with p
Supramolecule | Name: complex with p / type: complex / ID: 1 / Parent: 0 / Macromolecule list: all |
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Source (natural) | Organism: ![]() ![]() |
-Macromolecule #1: Synaptic vesicular amine transporter,transporter B
Macromolecule | Name: Synaptic vesicular amine transporter,transporter B / type: protein_or_peptide / ID: 1 / Number of copies: 1 / Enantiomer: LEVO |
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Source (natural) | Organism: ![]() ![]() |
Molecular weight | Theoretical: 61.926078 KDa |
Recombinant expression | Organism: ![]() ![]() |
Sequence | String: SRKLILFIVF LALLLDNMLL TVVVPIIPSY LYSIKHEKNA TEIQTARPVH TASISDSFQS IFSYYDNSTM VTGNATRDLT LHQTATQHM VTNASAVPSD CPSEDKDLLN ENVQVGLLFA SKATVQLITN PFIGLLTNRI GYPIPIFAGF CIMFVSTIMF A FSSSYAFL ...String: SRKLILFIVF LALLLDNMLL TVVVPIIPSY LYSIKHEKNA TEIQTARPVH TASISDSFQS IFSYYDNSTM VTGNATRDLT LHQTATQHM VTNASAVPSD CPSEDKDLLN ENVQVGLLFA SKATVQLITN PFIGLLTNRI GYPIPIFAGF CIMFVSTIMF A FSSSYAFL LIARSLQGIG SSCSSVAGMG MLASVYTDDE ERGNVMGIAL GGLAMGVLVG PPFGSVLYEF VGKTAPFLVL AA LVLLDGA IQLFVLQPSR VQPESQKGTP LTTLLKDPYI LIAAGSICFA NMGIAMLEPA LPIWMMETMC SRKWQLGVAF LPA SISYLI GTNIFGILAH KMGRWLCALL GMIIVGVSIL CIPFAKNIYG LIAPNFGVGF AIGMVDSSMM PIMGYLVDLR HVSV YGSVY AIADVAFCMG YAIGPSAGGA IAKAIGFPWL MTIIGIIDIL FAPLCFFLRS PPQVQLVESG GALVQPGGSL RLSCA ASGF PVNRYSMRWY RQAPGKEREW VAGMSSAGDR SSYEDSVKGR FTISRDDARN TVYLQMNSLK PEDTAVYYCN VNVGFE YWG QGTQVTVSSK UniProtKB: Synaptic vesicular amine transporter |
-Experimental details
-Structure determination
Method | ![]() |
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Aggregation state | particle |
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Sample preparation
Buffer | pH: 6.5 |
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Vitrification | Cryogen name: ETHANE |
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Electron microscopy
Microscope | FEI TITAN KRIOS |
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Electron beam | Acceleration voltage: 300 kV / Electron source: ![]() |
Electron optics | Illumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELD![]() |
Image recording | Film or detector model: GATAN K3 BIOQUANTUM (6k x 4k) / Average electron dose: 60.0 e/Å2 |
Experimental equipment | ![]() Model: Titan Krios / Image courtesy: FEI Company |
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Image processing
Startup model | Type of model: OTHER |
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Initial angle assignment | Type: RANDOM ASSIGNMENT |
Final angle assignment | Type: MAXIMUM LIKELIHOOD |
Final reconstruction | Resolution.type: BY AUTHOR / Resolution: 3.15 Å / Resolution method: FSC 0.143 CUT-OFF / Number images used: 232622 |