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- SASDGH2: Interleukin 11, N-terminally truncated (Interleukin 11, N-termina... -

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Open data


ID or keywords:

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Basic information

Entry
Database: SASBDB / ID: SASDGH2
SampleInterleukin 11, N-terminally truncated
  • Interleukin 11, N-terminal truncation (protein), IL11, Homo sapiens
Function / homology
Function and homology information


interleukin-11 receptor binding / cytokine activity / growth factor activity / cell population proliferation / positive regulation of MAPK cascade / positive regulation of cell population proliferation / cytoplasm
Similarity search - Function
Interleukin-11, mammalian / Interleukin-11 / Interleukin 11 / Four-helical cytokine-like, core
Similarity search - Domain/homology
Biological speciesHomo sapiens (human)
Contact author
  • Riley D. Metcalfe (Bio21 Institute, The University of Melbourne, Melbourne, Australia)

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

Downloads & links

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Models

Model #3564
Type: atomic / Chi-square value: 1.428 / P-value: 0.000626

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Sample

SampleName: Interleukin 11, N-terminally truncated / Specimen concentration: 5 mg/ml
BufferName: 20 mM Tris, 150 mM NaCl, 0.2% sodium azide / pH: 8.5
Entity #1804Name: IL11 / Type: protein / Description: Interleukin 11, N-terminal truncation / Formula weight: 18.249 / Num. of mol.: 1 / Source: Homo sapiens / References: UniProt: A8K3F7
Sequence:
GSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL

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Experimental information

BeamInstrument name: Australian Synchrotron SAXS/WAXS / City: Melbourne / : Australia / Type of source: X-ray synchrotronSynchrotron / Wavelength: 0.1078 Å / Dist. spec. to detc.: 2.038 mm
DetectorName: Dectris/Pilatus3 S 2M / Pixsize x: 172 mm
Scan
Title: Interleukin 11, N-terminally truncated / Measurement date: Jun 8, 2019 / Cell temperature: 20 °C / Exposure time: 1 sec. / Number of frames: 8 / Unit: 1/A /
MinMax
Q0.0074 0.6639
Distance distribution function P(R)
Sofotware P(R): GNOM 5.0 / Number of points: 458 /
MinMax
Q0.0103239 0.45859
P(R) point1 458
R0 54
Result
Type of curve: sec /
ExperimentalPorod
MW16.3 kDa13.6 kDa
Volume-21.7 nm3

P(R)GuinierGuinier error
Forward scattering, I00.006139 0.006122 2.4E-5
Radius of gyration, Rg1.76 nm1.743 nm0.011

MinMax
D-5.4
Guinier point4 70

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