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Yorodumi- SASDFZ9: RuvB-like 1 and 2, sperm-associated antigen 1 complex (His-RuvBL1... -
+Open data
-Basic information
Entry | Database: SASBDB / ID: SASDFZ9 |
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Sample | RuvB-like 1 and 2, sperm-associated antigen 1 complex (His-RuvBL1/RuvBL2/SPAG1)
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Function / homology | Function and homology information axonemal dynein complex assembly / promoter-enhancer loop anchoring activity / regulation of DNA strand elongation / positive regulation of telomere maintenance in response to DNA damage / establishment of protein localization to chromatin / R2TP complex / Swr1 complex / dynein axonemal particle / RPAP3/R2TP/prefoldin-like complex / regulation of double-strand break repair ...axonemal dynein complex assembly / promoter-enhancer loop anchoring activity / regulation of DNA strand elongation / positive regulation of telomere maintenance in response to DNA damage / establishment of protein localization to chromatin / R2TP complex / Swr1 complex / dynein axonemal particle / RPAP3/R2TP/prefoldin-like complex / regulation of double-strand break repair / positive regulation of telomerase RNA localization to Cajal body / Ino80 complex / protein folding chaperone complex / box C/D snoRNP assembly / NuA4 histone acetyltransferase complex / regulation of chromosome organization / positive regulation of double-strand break repair via homologous recombination / single fertilization / regulation of DNA replication / TFIID-class transcription factor complex binding / regulation of embryonic development / MLL1 complex / Telomere Extension By Telomerase / RNA polymerase II core promoter sequence-specific DNA binding / regulation of DNA repair / Deposition of new CENPA-containing nucleosomes at the centromere / positive regulation of DNA repair / TBP-class protein binding / DNA helicase activity / telomere maintenance / cellular response to estradiol stimulus / ADP binding / Formation of the beta-catenin:TCF transactivating complex / DNA Damage Recognition in GG-NER / euchromatin / negative regulation of canonical Wnt signaling pathway / chromatin DNA binding / beta-catenin binding / nuclear matrix / positive regulation of canonical Wnt signaling pathway / transcription corepressor activity / UCH proteinases / cellular response to UV / unfolded protein binding / nucleosome / protein folding / HATs acetylate histones / ATPase binding / spermatogenesis / regulation of apoptotic process / DNA recombination / DNA helicase / transcription coactivator activity / protein stabilization / regulation of cell cycle / hydrolase activity / Ub-specific processing proteases / chromatin remodeling / cadherin binding / cell cycle / ribonucleoprotein complex / RNA polymerase II cis-regulatory region sequence-specific DNA binding / cell division / DNA repair / centrosome / regulation of DNA-templated transcription / GTP binding / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / ATP hydrolysis activity / protein homodimerization activity / positive regulation of transcription by RNA polymerase II / extracellular exosome / nucleoplasm / ATP binding / membrane / identical protein binding / nucleus / cytosol / cytoplasm Similarity search - Function |
Biological species | Homo sapiens (human) |
Contact author |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Data source
SASBDB page | SASDFZ9 |
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-Related structure data
Similar structure data | Similarity search - Function & homologyF&H Search |
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-External links
Related items in Molecule of the Month |
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-Models
Model #2938 | Type: dummy / Radius of dummy atoms: 3.90 A / Chi-square value: 1.878 |
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-Sample
Sample | Name: RuvB-like 1 and 2, sperm-associated antigen 1 complex (His-RuvBL1/RuvBL2/SPAG1) Specimen concentration: 7 mg/ml / Entity id: 1608 / 1609 / 1792 |
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Buffer | Name: 20 mM HEPES, 150 mM NaCl, 1% glycerol, 5 mM TCEP / pH: 7.5 |
Entity #1608 | Type: protein / Description: RuvB-like 1 / Formula weight: 51.759 / Num. of mol.: 6 / Source: Homo sapiens / References: UniProt: Q9Y265 Sequence: MVHHHHHHLV PRGSKIEEVK STTKTQRIAS HSHVKGLGLD ESGLAKQAAS GLVGQENARE ACGVIVELIK SKKMAGRAVL LAGPPGTGKT ALALAIAQEL GSKVPFCPMV GSEVYSTEIK KTEVLMENFR RAIGLRIKET KEVYEGEVTE LTPCETENPM GGYGKTISHV ...Sequence: MVHHHHHHLV PRGSKIEEVK STTKTQRIAS HSHVKGLGLD ESGLAKQAAS GLVGQENARE ACGVIVELIK SKKMAGRAVL LAGPPGTGKT ALALAIAQEL GSKVPFCPMV GSEVYSTEIK KTEVLMENFR RAIGLRIKET KEVYEGEVTE LTPCETENPM GGYGKTISHV IIGLKTAKGT KQLKLDPSIF ESLQKERVEA GDVIYIEANS GAVKRQGRCD TYATEFDLEA EEYVPLPKGD VHKKKEIIQD VTLHDLDVAN ARPQGGQDIL SMMGQLMKPK KTEITDKLRG EINKVVNKYI DQGIAELVPG VLFVDEVHML DIECFTYLHR ALESSIAPIV IFASNRGNCV IRGTEDITSP HGIPLDLLDR VMIIRTMLYT PQEMKQIIKI RAQTEGINIS EEALNHLGEI GTKTTLRYSV QLLTPANLLA KINGKDSIEK EHVEEISELF YDAKSSAKIL ADQQDKYMK |
Entity #1609 | Type: protein / Description: RuvB-like 2 / Formula weight: 51.886 / Num. of mol.: 6 / Source: Homo sapiens / References: UniProt: Q9Y230 Sequence: MATVTATTKV PEIRDVTRIE RIGAHSHIRG LGLDDALEPR QASQGMVGQL AARRAAGVVL EMIREGKIAG RAVLIAGQPG TGKTAIAMGM AQALGPDTPF TAIAGSEIFS LEMSKTEALT QAFRRSIGVR IKEETEIIEG EVVEIQIDRP ATGTGSKVGK LTLKTTEMET ...Sequence: MATVTATTKV PEIRDVTRIE RIGAHSHIRG LGLDDALEPR QASQGMVGQL AARRAAGVVL EMIREGKIAG RAVLIAGQPG TGKTAIAMGM AQALGPDTPF TAIAGSEIFS LEMSKTEALT QAFRRSIGVR IKEETEIIEG EVVEIQIDRP ATGTGSKVGK LTLKTTEMET IYDLGTKMIE SLTKDKVQAG DVITIDKATG KISKLGRSFT RARDYDAMGS QTKFVQCPDG ELQKRKEVVH TVSLHEIDVI NSRTQGFLAL FSGDTGEIKS EVREQINAKV AEWREEGKAE IIPGVLFIDE VHMLDIESFS FLNRALESDM APVLIMATNR GITRIRGTSY QSPHGIPIDL LDRLLIVSTT PYSEKDTKQI LRIRCEEEDV EMSEDAYTVL TRIGLETSLR YAIQLITAAS LVCRKRKGTE VQVDDIKRVY SLFLDESRST QYMKEYQDAF LFNELKGETM DTSLEVLFQ |
Entity #1792 | Name: SPAG1 / Type: protein / Description: Sperm-associated antigen 1 / Formula weight: 103.929 / Num. of mol.: 1 / Source: Homo sapiens / References: UniProt: Q07617 Sequence: GPHMTTKDYP SLWGFGTTKT FKIPIEHLDF KYIEKCSDVK HLEKILCVLR SGEEGYYPEL TEFCEKHLQA LAPESRALRK DKPAATAASF TAEEWEKIDG DIKSWVSEIK KEEDKMHFHE TETFPAMKDN LPPVRGSNSC LHVGKEKYSK RPTKKKTPRD YAEWDKFDVE ...Sequence: GPHMTTKDYP SLWGFGTTKT FKIPIEHLDF KYIEKCSDVK HLEKILCVLR SGEEGYYPEL TEFCEKHLQA LAPESRALRK DKPAATAASF TAEEWEKIDG DIKSWVSEIK KEEDKMHFHE TETFPAMKDN LPPVRGSNSC LHVGKEKYSK RPTKKKTPRD YAEWDKFDVE KECLKIDEDY KEKTVIDKSH LSKIETRIDT AGLTEKEKDF LATREKEKGN EAFNSGDYEE AVMYYTRSIS ALPTVVAYNN RAQAEIKLQN WNSAFQDCEK VLELEPGNVK ALLRRATTYK HQNKLREATE DLSKVLDVEP DNDLAKKTLS EVERDLKNSE AASETQTKGK RMVIQEIENS EDEEGKSGRK HEDGGGDKKP AEPAGAARAA QPCVMGNIQK KLTGKAEGGK RPARGAPQRG QTPEAGADKR SPRRASAAAA AGGGATGHPG GGQGAENPAG LKSQGNELFR SGQFAEAAGK YSAAIALLEP AGSEIADDLS ILYSNRAACY LKEGNCSGCI QDCNRALELH PFSMKPLLRR AMAYETLEQY GKAYVDYKTV LQIDCGLQLA NDSVNRLSRI LMELDGPNWR EKLSPIPAVP ASVPLQAWHP AKEMISKQAG DSSSHRQQGI TDEKTFKALK EEGNQCVNDK NYKDALSKYS ECLKINNKEC AIYTNRALCY LKLCQFEEAK QDCDQALQLA DGNVKAFYRR ALAHKGLKNY QKSLIDLNKV ILLDPSIIEA KMELEEVTRL LNLKDKTAPF NKEKERRKIE IQEVNEGKEE PGRPAGEVSM GCLASEKGGK SSRSPEDPEK LPIAKPNNAY EFGQIINALS TRKDKEACAH LLAITAPKDL PMFLSNKLEG DTFLLLIQSL KNNLIEKDPS LVYQHLLYLS KAERFKMMLT LISKGQKELI EQLFEDLSDT PNNHFTLEDI QALKRQYEL |
-Experimental information
Beam | Instrument name: SOLEIL SWING / City: Saint-Aubin / 国: France / Type of source: X-ray synchrotronSynchrotron / Wavelength: 0.1033 Å / Dist. spec. to detc.: 2 mm | ||||||||||||||||||||||||||||||
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Detector | Name: Eiger 4M / Pixsize x: 75 mm | ||||||||||||||||||||||||||||||
Scan | Title: RuvB-like 1 and 2, sperm-associated antigen 1 complex (His-RuvBL1/RuvBL2/SPAG1) Measurement date: Mar 21, 2019 / Cell temperature: 15 °C / Exposure time: 1 sec. / Number of frames: 26 / Unit: 1/A /
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Distance distribution function P(R) | Sofotware P(R): GNOM 5.0 / Number of points: 248 /
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Result | Type of curve: sec /
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