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Yorodumi- ChemComp-H8G: N,N-diethyl-N'-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea -
+Open data
-Basic information
Entry | Database: PDB chemical components / ID: H8G | ||||
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Name | Name: Synonyms: lisuride Wikipedia | Wikipedia - Lisuride: Lisuride, sold under the brand name Dopergin among others, is a monoaminergic medication of the ergoline class which is used in the treatment of Parkinson's disease, migraine, and high prolactin levels. It is taken by mouth.
| Side effects of lisuride include nausea and vomiting, dizziness, headache, fatigue or drowsiness, insomnia or sleep, gastrointestinal disturbances such as abdominal pain or diarrhea, nasal congestion or runny nose, and hypotension, hallucinations or confusion (particularly at higher doses)... Comment | medication*YM | |
-Chemical information
Composition | Formula: C20H26N4O / Number of atoms: 51 / Formula weight: 338.447 / Formal charge: 0 | ||||||||
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Others | Type: NON-POLYMER / PDB classification: HETAIN / Three letter code: H8G / Ideal coordinates details: Corina / Model coordinates PDB-ID: 6DRX | ||||||||
History |
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External links | UniChem / BindingDB / Brenda / ChEBI / ChEMBL / CompTox / DrugBank / GtoPharmacology / HMDB / Nikkaji / PubChem / PubChem_TPharma / SureChEMBL / ZINC / ChemSpider / Wikipedia search / Google search |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Details
-SMILES
ACDLabs 12.01 | CACTVS 3.385 | OpenEye OEToolkits 2.0.6 | |
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-SMILES CANONICAL
CACTVS 3.385 | OpenEye OEToolkits 2.0.6 | |
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-InChI
InChI 1.03 |
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-InChIKey
InChI 1.03 |
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-SYSTEMATIC NAME
ACDLabs 12.01 | OpenEye OEToolkits 2.0.6 | |
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-PDB entries
Showing all 4 items
PDB-6drx:
Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor
PDB-7um6:
CryoEM structure of Go-coupled 5-HT5AR in complex with Lisuride
PDB-7wc7:
Crystal structure of serotonin 2A receptor in complex with lisuride
PDB-8uwl:
5-HT2AR bound to Lisuride in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)