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Yorodumi- ChemComp-FIL: (1E)-1-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]ETHANONE O-(AMINOCARBO... -
+Open data
-Basic information
Entry | Database: PDB chemical components / ID: FIL | ||||
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Name | Name: ( Synonyms: FILAMINAST Wikipedia | Wikipedia - Filaminast: Filaminast (code name WAY-PDA 641) was a drug candidate developed by Wyeth-Ayerst.: Table 2 It is a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and an analog of rolipram, which served as a prototype molecule for several development efforts.: 668, 678 It was discontinued after a Phase II trial showed that its therapeutic window was too narrow; it could not be dosed high enough without causing significant side effects (nausea and vomiting), which was a problem with the rolipram class of molecules.: 678 ... | Comment | inhibitor*YM | |
-Chemical information
Composition | Formula: C15H20N2O4 / Number of atoms: 41 / Formula weight: 292.33 / Formal charge: 0 | ||||||
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Others | Type: NON-POLYMER / PDB classification: HETAIN / Three letter code: FIL / Model coordinates PDB-ID: 1XLZ | ||||||
History |
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External links | UniChem / BindingDB / Brenda / ChEMBL / DrugBank / Nikkaji / PubChem / PubChem_TPharma / SureChEMBL / ZINC / ChemSpider / Wikipedia search / Google search |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Details
-SMILES
CACTVS 3.341 | OpenEye OEToolkits 1.5.0 | |
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-SMILES CANONICAL
CACTVS 3.341 | OpenEye OEToolkits 1.5.0 | |
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-InChI
InChI 1.03 |
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-InChIKey
InChI 1.03 |
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-PDB entries
Showing all 1 items
PDB-1xlz:
Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Filaminast