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Yorodumi- ChemComp-8QY: N-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-N'-[(2S)-1-(... -
+Open data
-Basic information
Entry | Database: PDB chemical components / ID: 8QY | ||||
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Name | Name: Wikipedia | Wikipedia - PZM21: PZM21 is an experimental opioid analgesic drug that is being researched for the treatment of pain.
It is claimed to be a functionally selective μ-opioid receptor agonist which produces μ-opioid receptor mediated G protein signaling, with potency and efficacy similar to morphine, but with less β-arrestin 2 recruitment. However, recent reports highlight that this might be due to its low intrinsic efficacy, rather than functional selectivity or 'G protein bias' as initially reported... | Comment | agonist*YM | |
-Chemical information
Composition | Formula: C19H27N3O2S / Number of atoms: 52 / Formula weight: 361.502 / Formal charge: 0 | ||||
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Others | Type: non-polymer / PDB classification: HETAIN / Three letter code: 8QY / Ideal coordinates details: Corina / Model coordinates PDB-ID: 7SBF | ||||
History |
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External links | UniChem / BindingDB / ChEMBL / ChemicalBook / DrugBank / GtoPharmacology / Nikkaji / PubChem / SureChEMBL / ZINC / ChemSpider / Wikipedia search / Google search |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Details
-SMILES
ACDLabs 12.01 | CACTVS 3.385 | OpenEye OEToolkits 2.0.7 | |
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-SMILES CANONICAL
CACTVS 3.385 | OpenEye OEToolkits 2.0.7 | |
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-InChI
InChI 1.03 |
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-InChIKey
InChI 1.03 |
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-SYSTEMATIC NAME
ACDLabs 12.01 | OpenEye OEToolkits 2.0.7 | |
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