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- EMDB-35823: Cryo-EM structure of the 48-nm repeat doublet microtubule from mo... -

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基本情報

登録情報
データベース: EMDB / ID: EMD-35823
タイトルCryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm
マップデータ
試料
  • 複合体: Mouse sperm DMT
    • タンパク質・ペプチド: x 49種
  • リガンド: x 3種
キーワードdoublet microtubule / STRUCTURAL PROTEIN (タンパク質)
機能・相同性
機能・相同性情報


male germ-line stem cell population maintenance / sperm flagellum assembly / outer dense fiber / axonemal A tubule inner sheath / manchette assembly / outer acrosomal membrane / axonemal B tubule inner sheath / regulation of brood size / establishment of left/right asymmetry / 9+0 motile cilium ...male germ-line stem cell population maintenance / sperm flagellum assembly / outer dense fiber / axonemal A tubule inner sheath / manchette assembly / outer acrosomal membrane / axonemal B tubule inner sheath / regulation of brood size / establishment of left/right asymmetry / 9+0 motile cilium / protein localization to motile cilium / left/right pattern formation / Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane / Cilium Assembly / Sealing of the nuclear envelope (NE) by ESCRT-III / epithelial cilium movement involved in determination of left/right asymmetry / regulation of calcineurin-NFAT signaling cascade / Intraflagellar transport / inner dynein arm assembly / Carboxyterminal post-translational modifications of tubulin / protein polyglutamylation / cilium-dependent cell motility / sperm axoneme assembly / positive regulation of feeding behavior / cerebrospinal fluid circulation / COPI-independent Golgi-to-ER retrograde traffic / regulation of cilium beat frequency involved in ciliary motility / sperm principal piece / MAP kinase tyrosine/serine/threonine phosphatase activity / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / cilium movement involved in cell motility / epithelial cilium movement involved in extracellular fluid movement / intraciliary transport / 9+2 motile cilium / regulation of store-operated calcium entry / PKR-mediated signaling / COPI-mediated anterograde transport / protein localization to organelle / Aggrephagy / 転移酵素; リンを含む基を移すもの / calcium ion sensor activity / ciliary transition zone / acrosomal membrane / Kinesins / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / Resolution of Sister Chromatid Cohesion / RHO GTPases activate IQGAPs / cilium movement / sperm DNA condensation / The role of GTSE1 in G2/M progression after G2 checkpoint / axoneme assembly / Recycling pathway of L1 / axonemal microtubule / cilium organization / left/right axis specification / flagellated sperm motility / COPI-dependent Golgi-to-ER retrograde traffic / gamma-tubulin ring complex / RHO GTPases Activate Formins / Separation of Sister Chromatids / Hedgehog 'off' state / Loss of Nlp from mitotic centrosomes / Recruitment of mitotic centrosome proteins and complexes / Loss of proteins required for interphase microtubule organization from the centrosome / Recruitment of NuMA to mitotic centrosomes / Anchoring of the basal body to the plasma membrane / AURKA Activation by TPX2 / Regulation of PLK1 Activity at G2/M Transition / manchette / nucleotide-activated protein kinase complex / positive regulation of cilium assembly / MHC class II antigen presentation / protein targeting to mitochondrion / CTP biosynthetic process / UTP biosynthetic process / 繊毛 / positive regulation of cell motility / protein targeting to membrane / negative regulation of TOR signaling / determination of left/right symmetry / GTP biosynthetic process / 微小管形成中心 / nucleoside diphosphate kinase activity / tubulin complex / regulation of neuron projection development / 中間径フィラメント / myosin phosphatase activity / extrinsic component of membrane / 細胞結合 / protein-serine/threonine phosphatase / beta-tubulin binding / AMP binding / regulation of cell division / receptor clustering / phosphatase activity / axoneme / mitotic cytokinesis / centriolar satellite / cilium assembly
類似検索 - 分子機能
Spermatid-specific manchette-related protein 1 / Testis-expressed sequence 37 protein / Testis-specific serine/threonine-protein kinase 6, catalytic domain / C10orf82-like / Spermatid-specific manchette-related protein 1 / TSC21 family / Protein phosphatase 1 regulatory subunit 32 / Testis, prostate and placenta-expressed protein / Testis-expressed protein 49 / Protein phosphatase 1 regulatory subunit 32 ...Spermatid-specific manchette-related protein 1 / Testis-expressed sequence 37 protein / Testis-specific serine/threonine-protein kinase 6, catalytic domain / C10orf82-like / Spermatid-specific manchette-related protein 1 / TSC21 family / Protein phosphatase 1 regulatory subunit 32 / Testis, prostate and placenta-expressed protein / Testis-expressed protein 49 / Protein phosphatase 1 regulatory subunit 32 / Protein of unknown function DUF1143 / Atypical dual specificity phosphatase, subfamily B / Protein of unknown function DUF4541 / Protein of unknown function DUF4513 / Cilia- and flagella-associated protein 68 / Sperm-associated microtubule inner protein 10 / Cilia and flagella associated protein 90 / Sperm-tail PG-rich repeat / DJBP, EF-hand domain / Tektin bundle interacting protein 1 / Coiled-coil domain-containing protein 105 / Sperm-tail PG-rich repeat / EF-hand domain / Tektin bundle interacting protein 1 / FAM183 family / FAM183A and FAM183B related / Sperm-associated antigen 8 / Cilia- and flagella-associated protein 95 / NDPK7, first NDPk domain / Cilia- and flagella-associated protein 107 / : / Protein CFAP95 / Tektin / Cilia- and flagella-associated protein 276 / Tektin family / Protein of unknown function (DUF3695) / Cilia- and flagella-associated protein 77 / Cilia- and flagella-associated protein 77 / Uncharacterised protein FAM166/UPF0605 / Protein Flattop / Ciliary microtubule inner protein 2B-like / Nucleoside diphosphate kinase 7 / Meiosis-specific nuclear structural protein 1 / Piercer of microtubule wall 1/2 / Cilia- and flagella-associated protein 141 / Cilia- and flagella-associated protein 45 / NDPK7, second NDPk domain / Cilia- and flagella- associated protein 210 / CFAP53/TCHP / Trichohyalin-plectin-homology domain / Trichohyalin-plectin-homology domain / Piercer of microtubule wall 1/2 / Cilia- and flagella-associated protein 141 / RIB43A / RIB43A / DM10 domain / EF-hand domain-containing protein EFHC1/EFHC2/EFHB / DM10 domain / DM10 domain profile. / Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases. / Enkurin domain / Calmodulin-binding / Enkurin domain profile. / CFA20 domain / Cilia- and flagella-associated protein 20/CFAP20DC / CFA20 domain / Parkin co-regulated protein / Parkin co-regulated protein / Dual specificity phosphatase, catalytic domain / Nucleoside diphosphate kinase (NDPK)-like domain profile. / EFハンド / Dual specificity phosphatase, catalytic domain / Dual specificity phosphatase, catalytic domain / Dual specificity protein phosphatase domain / Dual specificity protein phosphatase domain profile. / Nucleoside diphosphate kinase / Nucleoside diphosphate kinase-like domain / Nucleoside diphosphate kinase / NDK / Nucleoside diphosphate kinase-like domain superfamily / EF-hand domain pair / Mir domain superfamily / Tubulin-beta mRNA autoregulation signal. / Alpha tubulin / Beta tubulin, autoregulation binding site / Beta tubulin / チューブリン / Tubulin, C-terminal / Tubulin C-terminal domain / Tubulin, conserved site / Tubulin subunits alpha, beta, and gamma signature. / Tyrosine specific protein phosphatases active site. / Protein-tyrosine phosphatase, active site / Tubulin/FtsZ family, C-terminal domain / Tubulin/FtsZ-like, C-terminal domain / Tyrosine-specific protein phosphatases domain / Tyrosine specific protein phosphatases domain profile. / Tubulin/FtsZ, C-terminal / Tubulin/FtsZ, 2-layer sandwich domain / Tubulin/FtsZ family, GTPase domain
類似検索 - ドメイン・相同性
Cilia and flagella associated protein 77 / Cilia- and flagella- associated protein 210 / Tektin bundle-interacting protein 1 / Family with sequence similarity 183, member B / Tektin-5 / Tubulin alpha-3 chain / Tubulin beta-4B chain / Protein phosphatase 1 regulatory subunit 32 / Tektin-4 / Spermatid-specific manchette-related protein 1 ...Cilia and flagella associated protein 77 / Cilia- and flagella- associated protein 210 / Tektin bundle-interacting protein 1 / Family with sequence similarity 183, member B / Tektin-5 / Tubulin alpha-3 chain / Tubulin beta-4B chain / Protein phosphatase 1 regulatory subunit 32 / Tektin-4 / Spermatid-specific manchette-related protein 1 / Sperm-associated antigen 8 / Cilia- and flagella-associated protein 107 / Piercer of microtubule wall 1 protein / Cilia- and flagella-associated protein 52 / Meiosis-specific nuclear structural protein 1 / Testis, prostate and placenta-expressed protein / EF-hand calcium-binding domain-containing protein 6 / Protein Flattop / Cilia- and flagella-associated protein 161 / Enkurin / Tektin-3 / Cilia- and flagella-associated protein 20 / Testis expressed 49 / EF-hand domain-containing family member B / Outer dense fiber protein 3 / Tektin-2 / Testis-specific serine/threonine-protein kinase 6 / Cilia- and flagella-associated protein 95 / Uncharacterized protein C10orf82 homolog / RIB43A-like with coiled-coils protein 1 / Cilia- and flagella-associated protein 68 / Cilia- and flagella-associated protein 53 / EF-hand domain-containing family member C2 / Ciliary microtubule inner protein 2A / Tektin-like protein 1 / RIB43A-like with coiled-coils protein 2 / Dual specificity phosphatase 21 / Cilia- and flagella-associated protein 141 / Sperm-associated microtubule inner protein 10 / EF-hand domain-containing protein 1 / Cilia- and flagella-associated protein 45 / Cilia- and flagella-associated protein 276 / Testis-expressed sequence 37 protein / Tektin-1 / Parkin coregulated gene protein homolog / Cilia- and flagella-associated protein 90 / Ciliary microtubule inner protein 2C / Nucleoside diphosphate kinase homolog 7 / Piercer of microtubule wall 2 protein
類似検索 - 構成要素
生物種Mus musculus (ハツカネズミ) / house mouse (ハツカネズミ)
手法単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.5 Å
データ登録者Zhou LN / Gui M / Wu JP
資金援助 中国, 1件
OrganizationGrant number国
National Natural Science Foundation of China (NSFC) 中国
引用ジャーナル: Cell / 年: 2023
タイトル: Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility.
著者: Lunni Zhou / Haobin Liu / Siyu Liu / Xiaoyu Yang / Yue Dong / Yun Pan / Zhuang Xiao / Beihong Zheng / Yan Sun / Pengyu Huang / Xixi Zhang / Jin Hu / Rui Sun / Shan Feng / Yi Zhu / Mingxi Liu ...著者: Lunni Zhou / Haobin Liu / Siyu Liu / Xiaoyu Yang / Yue Dong / Yun Pan / Zhuang Xiao / Beihong Zheng / Yan Sun / Pengyu Huang / Xixi Zhang / Jin Hu / Rui Sun / Shan Feng / Yi Zhu / Mingxi Liu / Miao Gui / Jianping Wu /
要旨: Sperm motility is crucial for successful fertilization. Highly decorated doublet microtubules (DMTs) form the sperm tail skeleton, which propels the movement of spermatozoa. Using cryo-electron ...Sperm motility is crucial for successful fertilization. Highly decorated doublet microtubules (DMTs) form the sperm tail skeleton, which propels the movement of spermatozoa. Using cryo-electron microscopy (cryo-EM) and artificial intelligence (AI)-based modeling, we determined the structures of mouse and human sperm DMTs and built an atomic model of the 48-nm repeat of the mouse sperm DMT. Our analysis revealed 47 DMT-associated proteins, including 45 microtubule inner proteins (MIPs). We identified 10 sperm-specific MIPs, including seven classes of Tektin5 in the lumen of the A tubule and FAM166 family members that bind the intra-tubulin interfaces. Interestingly, the human sperm DMT lacks some MIPs compared with the mouse sperm DMT. We also discovered variants in 10 distinct MIPs associated with a subtype of asthenozoospermia characterized by impaired sperm motility without evident morphological abnormalities. Our study highlights the conservation and tissue/species specificity of DMTs and expands the genetic spectrum of male infertility.
履歴
登録2023年4月5日-
ヘッダ(付随情報) 公開2023年7月5日-
マップ公開2023年7月5日-
更新2023年7月5日-
現状2023年7月5日処理サイト: PDBj / 状態: 公開

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構造の表示

添付画像

emd_35823.png

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マップ

ファイルダウンロード / ファイル: emd_35823.map.gz / 形式: CCP4 / 大きさ: 689 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
ボクセルのサイズX=Y=Z: 1.087 Å
密度
表面レベル登録者による: 0.3
最小 - 最大0.0 - 2.8214865
平均 (標準偏差)0.0727588 (±0.17619546)
対称性空間群: 1
詳細

EMDB XML:

マップ形状
Axis orderXYZ
Origin2041330
サイズ426530800
Spacing530426800
セルA: 576.11 Å / B: 463.062 Å / C: 869.60004 Å
α=β=γ: 90.0 °

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添付データ

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試料の構成要素

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全体 : Mouse sperm DMT

全体名称: Mouse sperm DMT
要素
  • 複合体: Mouse sperm DMT
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 95
    • タンパク質・ペプチド: EF-hand domain-containing family member B
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 53
    • タンパク質・ペプチド: Nucleoside diphosphate kinase 7Nucleoside-diphosphate kinase
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 107
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 141
    • タンパク質・ペプチド: Tektin-1
    • タンパク質・ペプチド: Tubulin alpha-3 chain
    • タンパク質・ペプチド: Tubulin beta-4B chain
    • タンパク質・ペプチド: Meiosis-specific nuclear structural protein 1
    • タンパク質・ペプチド: Tektin-2
    • タンパク質・ペプチド: Tektin-3
    • タンパク質・ペプチド: Sperm-associated antigen 8
    • タンパク質・ペプチド: Tektin-4
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 161
    • タンパク質・ペプチド: Piercer of microtubule wall 2 protein
    • タンパク質・ペプチド: Protein FAM166A
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 68
    • タンパク質・ペプチド: Cilia and flagella-associated protein 77
    • タンパク質・ペプチド: Family with sequence similarity 183, member B
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 90
    • タンパク質・ペプチド: Protein FAM166C
    • タンパク質・ペプチド: RIB43A-like with coiled-coils protein 1
    • タンパク質・ペプチド: Dual specificity phosphatase 21
    • タンパク質・ペプチド: EF-hand domain-containing protein 1
    • タンパク質・ペプチド: Testis expressed 49
    • タンパク質・ペプチド: Testis-expressed sequence 37 protein
    • タンパク質・ペプチド: Tektin bundle-interacting protein 1
    • タンパク質・ペプチド: RIB43A-like with coiled-coils protein 2
    • タンパク質・ペプチド: Tektin-5
    • タンパク質・ペプチド: EF-hand domain-containing family member C2
    • タンパク質・ペプチド: Spermatid-specific manchette-related protein 1
    • タンパク質・ペプチド: Protein phosphatase 1 regulatory subunit 32
    • タンパク質・ペプチド: Testis-specific serine/threonine-protein kinase 6
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 20
    • タンパク質・ペプチド: Outer dense fiber protein 3
    • タンパク質・ペプチド: Parkin coregulated gene protein homolog
    • タンパク質・ペプチド: Testis, prostate and placenta-expressed protein精巣
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 45
    • タンパク質・ペプチド: Uncharacterized protein C10orf82 homolog
    • タンパク質・ペプチド: Coiled-coil domain-containing protein 105
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 52
    • タンパク質・ペプチド: Enkurin
    • タンパク質・ペプチド: Testis-expressed protein 43
    • タンパク質・ペプチド: Protein Flattop
    • タンパク質・ペプチド: EF-hand calcium-binding domain-containing protein 6
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 210
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 276
    • タンパク質・ペプチド: Piercer of microtubule wall 1 protein
  • リガンド: GUANOSINE-5'-TRIPHOSPHATEグアノシン三リン酸
  • リガンド: MAGNESIUM ION
  • リガンド: GUANOSINE-5'-DIPHOSPHATE

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超分子 #1: Mouse sperm DMT

超分子名称: Mouse sperm DMT / タイプ: complex / ID: 1 / 親要素: 0 / 含まれる分子: #1-#49
由来(天然)生物種: Mus musculus (ハツカネズミ)

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分子 #1: Cilia- and flagella-associated protein 95

分子名称: Cilia- and flagella-associated protein 95 / タイプ: protein_or_peptide / ID: 1 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 26.633035 KDa
配列文字列: MGTFDSQCHE CFESKERWYE IGPTDLLERK GSLTLRSHHK KYSEPVLVYS WHRNREAFPK DYDIESLETV KNLCMSTYKR FGSDSPRWM SEAREQMAQV LVNKDLVEKK KTGLLDEETL CPGILERDPE LPPTGFRDVP MESPPDPRKP CFSTTYSEDF T PQYEYPPP ...文字列:
MGTFDSQCHE CFESKERWYE IGPTDLLERK GSLTLRSHHK KYSEPVLVYS WHRNREAFPK DYDIESLETV KNLCMSTYKR FGSDSPRWM SEAREQMAQV LVNKDLVEKK KTGLLDEETL CPGILERDPE LPPTGFRDVP MESPPDPRKP CFSTTYSEDF T PQYEYPPP ACPRREEYSI VHRKCRSQFT DLNGSKRLGI NTWHDESGIY ANSEAKQKLY ALARNPIVPF

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分子 #2: EF-hand domain-containing family member B

分子名称: EF-hand domain-containing family member B / タイプ: protein_or_peptide / ID: 2 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 95.891961 KDa
配列文字列: MCSFVRVGSP KPLQTSASPL EMSSLRRTRA PEISELGLTP EQKDDIRDRV LRGSKSPTEL GFDLRLEQDR KWRERMGSSE AKSPPCHAL GVGLERHTIS GTPTEMGNLG LHKGSAFQGS KPLGVLPGRV GPENKGLPPR LRYGGTLHPP FSTVHASPLA A ESRRRPLA ...文字列:
MCSFVRVGSP KPLQTSASPL EMSSLRRTRA PEISELGLTP EQKDDIRDRV LRGSKSPTEL GFDLRLEQDR KWRERMGSSE AKSPPCHAL GVGLERHTIS GTPTEMGNLG LHKGSAFQGS KPLGVLPGRV GPENKGLPPR LRYGGTLHPP FSTVHASPLA A ESRRRPLA WGSAWTDAVV EKQPVVGLEL RKEPEKEPTC VVMNPYPEMP PKEVDIGLPQ TQESDEAKNT EPLIGLVREP SE CPFAQQP EEKKEPGSTE PGVEPPGNIR PIYSGKFFDR VPCWPSAGKV KPVGYRVATC LTEKLPRLMT PPEAKKYFNF RYP PAGAER VFYGRANDPQ IAPYLTHGLR SKISIPMGSL INPQPITTFQ QKIKDKKESI YFSHQRAPLG KSHDQTPGLP KGMD VINTT LGTPTIRELS VRDTVNPSKS FEDVLKEGQE GHDLYTVSHN DYFAGEAKNR KYNPASFHRF NLYGIPTPHF NDGRT MAKA LHWLHELQME RGAKIVSKRV DDFKEKFQHK LGKVLDPIAE TMNVPPGHTF GSCLHPEEYG AGDLIHYRSP DEYLRG KDH QRAVVAAARH HLKKFNHQNF DTLQVAFRHY DKKGDGVIDR AELHEACVQA NLHLDKMLLD HLFDYCDVDQ DGLINYL EF ANFLNWKDRI PLKEHEKRVV VKGKKPDCEN VTDTSMGEAE PSLLINPEDI VPKEPGSSEE TLRTIQRPGD KVSHQYKT T SSEINAVVGA VPSMCHPIFG VPTIRSDISA PRIRRVSDMN NYGDEGNAYS LLHPSIFSQK GVFERDFFKT RSKEEISDI LTNIGVKLSK EEFENVWNLA SKKHQRGEVC VETIRNVLDE LLHADLVKCK TAM

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分子 #3: Cilia- and flagella-associated protein 53

分子名称: Cilia- and flagella-associated protein 53 / タイプ: protein_or_peptide / ID: 3 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 62.036609 KDa
配列文字列: MYSQQFGTVP REFKGPTPKA VIIRAKPPKA QRAEQHLKRI QRSYHKYHTT LASIKSNEEN RLKCDWIQRN NHKTFDSLVQ ARVQDAMQG FVINTEERRN KLRELLASEE NEYFSEMQLK GETIEEKKDK MRERTKLLRE KKEKERQEFV AEKLDQQFRE R CEELRTKL ...文字列:
MYSQQFGTVP REFKGPTPKA VIIRAKPPKA QRAEQHLKRI QRSYHKYHTT LASIKSNEEN RLKCDWIQRN NHKTFDSLVQ ARVQDAMQG FVINTEERRN KLRELLASEE NEYFSEMQLK GETIEEKKDK MRERTKLLRE KKEKERQEFV AEKLDQQFRE R CEELRTKL ASIHEKKVVE ERNAQIEFNK ELKRQKLVEE HLFARLWEED RLAKERREAQ EEKRQRELVQ NTRLGLDAQV TS IQAQRQG ARRMKEEEAR ILEQNKAQIK REDEQEKLQK QKRRQETRSS LKKAVQDKIE SMQREYREDL DLNMKLVGRA LQD LQDEAD KKKQKREEMG REQKIYNDYL MQRREEEKAQ EKELNRLLED IKAKKLAEKD RELALQRAAR KQLMNEVMNT RKLQ VQERL QRKLREQEEL ALHEQRISES LKVLHQEDME DFARRCALAE EYRNQLQMQI AHQQQAREAE KEEERQEFEA GLAAN KACL DKIQRILSEN QALSQNVHPM RRGYPDKPPL

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分子 #4: Nucleoside diphosphate kinase 7

分子名称: Nucleoside diphosphate kinase 7 / タイプ: protein_or_peptide / ID: 4 / コピー数: 3 / 光学異性体: LEVO / EC番号: nucleoside-diphosphate kinase
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 44.489828 KDa
配列文字列: MRACQQGRSS SLVSPYMAPK NQSERFAFIA EWYDPNASLL RRYELLFYPV DGSVEMHDVK NRRTFLKRTK YEDLRLEDLF IGNKVNVFS RQLVLIDYGD QYTARQLGSR KEKTLALIKP DAVSKAGEII EMINKSGFTI TKLRMMTLTR KEAADFHVDH H SRPFYNEL ...文字列:
MRACQQGRSS SLVSPYMAPK NQSERFAFIA EWYDPNASLL RRYELLFYPV DGSVEMHDVK NRRTFLKRTK YEDLRLEDLF IGNKVNVFS RQLVLIDYGD QYTARQLGSR KEKTLALIKP DAVSKAGEII EMINKSGFTI TKLRMMTLTR KEAADFHVDH H SRPFYNEL IQFITSGPVI AMEILRDDAI CEWKRLLGPA NSGLSRTDAP GSIRALFGTD GVRNAAHGPD TFASAAREME LF FPSSGGC GPANTAKFTN CTCCIIKPHA ISEGMLGKNL IAIRDACFGM SAIQMFNLDR ANVEEFYEVY KGVVSEYNDM VTE LCSGPC VAIEIQQSNP TKTFREFCGP ADPEIARHLR PETLRAIFGK TKVQNAVHCT DLPEDGLLEV QYFFKILDN

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分子 #5: Cilia- and flagella-associated protein 107

分子名称: Cilia- and flagella-associated protein 107 / タイプ: protein_or_peptide / ID: 5 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 23.06251 KDa
配列文字列: MAMLSTSVVP EAFSTPGWQI EKKYSTKVLL GNWVEERGKF TKAIDHTPQC IYRKEYVPMP DHRPDFVSRW YSKSKMEGLP YKHLITHHQ EPSHRYLIST YDDHYNRHNY NPGLPALRTW NGQKLLWLPE KSDFPLVAPP TNYGLLEQLQ QKWLASKTSL K ESIYTTSY ...文字列:
MAMLSTSVVP EAFSTPGWQI EKKYSTKVLL GNWVEERGKF TKAIDHTPQC IYRKEYVPMP DHRPDFVSRW YSKSKMEGLP YKHLITHHQ EPSHRYLIST YDDHYNRHNY NPGLPALRTW NGQKLLWLPE KSDFPLVAPP TNYGLLEQLQ QKWLASKTSL K ESIYTTSY PRLPVCAMSR REHAIPVPHP RLQPIPRF

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分子 #6: Cilia- and flagella-associated protein 141

分子名称: Cilia- and flagella-associated protein 141 / タイプ: protein_or_peptide / ID: 6 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 12.278145 KDa
配列文字列:
MSAEKMTKLE ENLQRAVALK KTVDRWRNFH IHCMWQTTLD QRRNLFAALR MKDTKEQELA LSNKQLLVVR QAALHELFEK EYQQYQQEL NQMGKAFYEE RL

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分子 #7: Tektin-1

分子名称: Tektin-1 / タイプ: protein_or_peptide / ID: 7 / コピー数: 6 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 48.713035 KDa
配列文字列: MAKLLQSPPR FLPEEWYIAN KSQYHRAEAQ RSQSERLVAE SQRLVEEIEK TTRKSQSDVN KKLEQRLEEV RFWKKELDDK LEQLVNQTD DLLTYKTRLE RSLESYKEPL HITEKCLEYR EKRVGIDLVH DVVEQELQKE ADIIHGVMNL LIRTLEESTE Q IRLNRSAK ...文字列:
MAKLLQSPPR FLPEEWYIAN KSQYHRAEAQ RSQSERLVAE SQRLVEEIEK TTRKSQSDVN KKLEQRLEEV RFWKKELDDK LEQLVNQTD DLLTYKTRLE RSLESYKEPL HITEKCLEYR EKRVGIDLVH DVVEQELQKE ADIIHGVMNL LIRTLEESTE Q IRLNRSAK YNLEKDLRDK FTAITIDDVC FSLNNNSPNI NFSEKVVRIE PNSVSLEDWL DFSNANVEKA DKQLNNSTAL KT LVDQILS QTANDLRRQC EVVDEAFING LKETKDARNK LADHLAKVME EIASQEKNIM ALENAITQQE GPAKVAHTRL ETR THRPNV ELCRDIAQYR LIKEIQEINH NVARLKETLA QAQTQLKALY RRQLALQEEI QVKENTIYID QVLCMEMRKS IPPR DGDDH GAWEGGIRAE AIC

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分子 #8: Tubulin alpha-3 chain

分子名称: Tubulin alpha-3 chain / タイプ: protein_or_peptide / ID: 8 / コピー数: 178 / 光学異性体: LEVO
EC番号: 加水分解酵素; 酸無水物に作用; GTPに作用・細胞または細胞小器官の運動に関与
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 50.012359 KDa
配列文字列: MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVVDEVRT GTYRQLFHP EQLITGKEDA ANNYARGHYT IGKEIVDLVL DRIRKLADLC TGLQGFLIFH SFGGGTGSGF ASLLMERLSV D YGKKSKLE ...文字列:
MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVVDEVRT GTYRQLFHP EQLITGKEDA ANNYARGHYT IGKEIVDLVL DRIRKLADLC TGLQGFLIFH SFGGGTGSGF ASLLMERLSV D YGKKSKLE FAIYPAPQVS TAVVEPYNSI LTTHTTLEHS DCAFMVDNEA IYDICRRNLD IERPTYTNLN RLIGQIVSSI TA SLRFDGA LNVDLTEFQT NLVPYPRIHF PLATYAPVIS AEKAYHEQLS VAEITNACFE PANQMVKCDP RHGKYMACCM LYR GDVVPK DVNAAIATIK TKRTIQFVDW CPTGFKVGIN YQPPTVVPGG DLAKVQRAVC MLSNTTAIAE AWARLDHKFD LMYA KRAFV HWYVGEGMEE GEFSEAREDL AALEKDYEEV GVDSVEAEAE EGEEY

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分子 #9: Tubulin beta-4B chain

分子名称: Tubulin beta-4B chain / タイプ: protein_or_peptide / ID: 9 / コピー数: 176 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 49.877824 KDa
配列文字列: MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY YNEATGGKYV PRAVLVDLEP GTMDSVRSGP FGQIFRPDN FVFGQSGAGN NWAKGHYTEG AELVDSVLDV VRKEAESCDC LQGFQLTHSL GGGTGSGMGT LLISKIREEY P DRIMNTFS ...文字列:
MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY YNEATGGKYV PRAVLVDLEP GTMDSVRSGP FGQIFRPDN FVFGQSGAGN NWAKGHYTEG AELVDSVLDV VRKEAESCDC LQGFQLTHSL GGGTGSGMGT LLISKIREEY P DRIMNTFS VVPSPKVSDT VVEPYNATLS VHQLVENTDE TYCIDNEALY DICFRTLKLT TPTYGDLNHL VSATMSGVTT CL RFPGQLN ADLRKLAVNM VPFPRLHFFM PGFAPLTSRG SQQYRALTVP ELTQQMFDAK NMMAACDPRH GRYLTVAAVF RGR MSMKEV DEQMLNVQNK NSSYFVEWIP NNVKTAVCDI PPRGLKMSAT FIGNSTAIQE LFKRISEQFT AMFRRKAFLH WYTG EGMDE MEFTEAESNM NDLVSEYQQY QDATAEEEGE FEEEAEEEVA

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分子 #10: Meiosis-specific nuclear structural protein 1

分子名称: Meiosis-specific nuclear structural protein 1 / タイプ: protein_or_peptide / ID: 10 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 60.353012 KDa
配列文字列: MATKKRALSF SEKHQKLVDE KFRKSLNIQV MNKLERQAKN QVVQNENDEK VERQRFLRVL QNEQFELDME EAIQKAEANK MLRDRQLEQ EERLANELAR LKHESLKDKK MRQQVRENSI ELRELEQKLK AAYMNKERAA QIVEKDAMKY EQMKRDAEIE R IMMEEHDR ...文字列:
MATKKRALSF SEKHQKLVDE KFRKSLNIQV MNKLERQAKN QVVQNENDEK VERQRFLRVL QNEQFELDME EAIQKAEANK MLRDRQLEQ EERLANELAR LKHESLKDKK MRQQVRENSI ELRELEQKLK AAYMNKERAA QIVEKDAMKY EQMKRDAEIE R IMMEEHDR LLKEESAKQE RRNKERAQYY LDLEKQLEDQ ERRKQEAYEQ LLKEKLMIDE IVRKIYEEDQ VERQQKLEKK NA IQKYIEE FQRAQDFWRQ KKREEMEEEN RKIIEFANIQ EQREGERMAR VHEIEEKRVQ RQNLLMKQLE ETLRQRDDLE QVR QELYQE EQAEIIKLKV KEEAELRLRR QREMKQDFED QMALKELILQ AAKEEEETFK KAMLAKFAED DRIELMNAQK QRMK QLEHK RAVEKLIEER RSQFLADKQR ELEELQLQQR RQGCINEIIE EERLRLLKEH AAKLLGYLPK GVFKREDDVD MLGEE FRKA YQKRDGV

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分子 #11: Tektin-2

分子名称: Tektin-2 / タイプ: protein_or_peptide / ID: 11 / コピー数: 12 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 50.385066 KDa
配列文字列: MATLSFKPSE RYRLSDWRTN SYLLSTNAER QRDASHQIRQ EARILRNETN NQIVWDEHDN RTRLAERIDT VNRWKETLDK CLTDLDAEI DSLAQAKESA EQNLQAKNLP LDVAIECLTL RESRRDIDVV RDPVEEELLK EVEVIEATKK VLQEKISQAF Q HLCLLQEI ...文字列:
MATLSFKPSE RYRLSDWRTN SYLLSTNAER QRDASHQIRQ EARILRNETN NQIVWDEHDN RTRLAERIDT VNRWKETLDK CLTDLDAEI DSLAQAKESA EQNLQAKNLP LDVAIECLTL RESRRDIDVV RDPVEEELLK EVEVIEATKK VLQEKISQAF Q HLCLLQEI RQQLNSDHRD KMETLEIDRG CLSLNLTSPN ISLKVNPTRI PKDSTTLQQW DEFTRFNKNR AEAEMKASIE LR EAIALAI AQTNNELDAQ RVATEFTFRK RLREMESFYS ELKWQEKNTL EEIAELQGDI RRLEEDLRRK MMNLKLAHTR LES RTYRSN VELCRDQTQY GLIDEVHQLE ATINTMKQKL AQTQNALDAL FKHLARIQAD IACKTNTLLL DTKCMDTRRK LTVP AEKFV PQVDTFTRTT NRTLSPLKIC QLELT

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分子 #12: Tektin-3

分子名称: Tektin-3 / タイプ: protein_or_peptide / ID: 12 / コピー数: 17 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 56.754777 KDa
配列文字列: MELLGSTLTA TYAHPPPASA SFLPAIGTIT SSYKDRFPHR NLTHSLSLPW RPNTYYKTAY NYPTLAPYSS RSQRVCESTM LPFVSNRTT FFTRYTPDDW YRSNLVSFQE SNSSRHNSER LRVDTSRLIQ DKYQQIRKTQ AHSTQNLGER VNDLAFWKSE I THELDEMI ...文字列:
MELLGSTLTA TYAHPPPASA SFLPAIGTIT SSYKDRFPHR NLTHSLSLPW RPNTYYKTAY NYPTLAPYSS RSQRVCESTM LPFVSNRTT FFTRYTPDDW YRSNLVSFQE SNSSRHNSER LRVDTSRLIQ DKYQQIRKTQ AHSTQNLGER VNDLAFWKSE I THELDEMI GETNALTDIK RRLERGLIET EGPLQVSREC LFHREKRMGI DLVHDEAEKE LLAEVDTILC CQERMRQHLD KA NAQLASD RSAQHELEKD LSDKQAALRI DDKCQHLRNT SEGVSYFRGV ERVDATVSVP ETWAKFTDDN VLRSQSERAA SAK LREETE NLLIVTANEM WNQFNKVNLA FTNRIAETVD AKNKIHTHLT KTLQEIFQIE MTIESIKKAI KEKSAFLKVA QTRL DERTR RPNVELCRDM AQLRLVNEVY EVDETIQTLQ QRLRDSEDTL QSLAHTKATL EHDLAVKANT LYIDQEKCMS MRNSY PSTL RLVGYC

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分子 #13: Sperm-associated antigen 8

分子名称: Sperm-associated antigen 8 / タイプ: protein_or_peptide / ID: 13 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 50.591805 KDa
配列文字列: METTESTEGS LSRSCDVQPS SERLDTPSEP VPSSSSSPRS TAPAEAPAQY SVLTEPSSDS LYGAPCPPAH HRGHGFGFQP FYVSCIPQD PCNMADLSSR ADPTSSYPCH SSVHGSGSGT CGLGQSSEPS QGSGPTSGPA PASVPSLVSG PDSASGPDSS A SGPALASG ...文字列:
METTESTEGS LSRSCDVQPS SERLDTPSEP VPSSSSSPRS TAPAEAPAQY SVLTEPSSDS LYGAPCPPAH HRGHGFGFQP FYVSCIPQD PCNMADLSSR ADPTSSYPCH SSVHGSGSGT CGLGQSSEPS QGSGPTSGPA PASVPSLVSG PDSASGPDSS A SGPALASG PGPADPGQGP KFSTCIPQGY RCIPVDLAPD YNAWCQHLHW KPQRSWEPLQ VSEPGVRGPY KPPEPGALGP CE PCEPCEP PEAESEETLC KARPRGQCLL YNWEEERATN QLDQIPPLQD GSESYFFRHG HQGLLTTQPQ SPMSSSTTQR DSY QLPRHI CQPLRGKREA MLEMLLRHQI CKEVQAEQEP ARKLFETESV THHDYRVELV RAAPPASTKP HDYRQEQPET FWIQ RAARL PGVSDIRTLD TPFRKNCSFS TPVPLSLGQP LPYELESGPH QVGVISSLAC QGGGQGCGRT KTTPI

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分子 #14: Tektin-4

分子名称: Tektin-4 / タイプ: protein_or_peptide / ID: 14 / コピー数: 12 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 52.121449 KDa
配列文字列: MAQTGVLLTK EPAPQSIDVC ELPRKEYEVA CNTGAYTSSG LATAGFRTAK YLRDEWFQNS YARYHQAFAD RDYSERQRHE SGQLVAETG ALAQRTQLDS TRKVGERLED MHCWKSELQR EIDELSSETD LMMAQKLRLQ RALDATSVPY SIATDNLQCR E RRQHPDLV ...文字列:
MAQTGVLLTK EPAPQSIDVC ELPRKEYEVA CNTGAYTSSG LATAGFRTAK YLRDEWFQNS YARYHQAFAD RDYSERQRHE SGQLVAETG ALAQRTQLDS TRKVGERLED MHCWKSELQR EIDELSSETD LMMAQKLRLQ RALDATSVPY SIATDNLQCR E RRQHPDLV RDYVEVELLK ETELIRNIQE LLKRTIGQAV DQIRLNREHK ESCEMNWSDK VEVYNIDDTC SRYTNESTQV QF YPHSSKF EESASTPETW AKFNHDNLLR AERERLASVN LRKLIDCILR DTAEDLRLQC DAVNSAFSSR CQELDDSLQK LQY HLRKTL TEITDQEHQI AALKQAIKDK EAPLRVAQTR LYQRSHRPNV ELCRDNAQFR LLSEVEELNM SLRALKEKLQ DAEQ ALRNL EDSRMSLEKD IAVKTNSLFI DRQKCMTHRN RYPSVLQLAG YQ

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分子 #15: Cilia- and flagella-associated protein 161

分子名称: Cilia- and flagella-associated protein 161 / タイプ: protein_or_peptide / ID: 15 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 34.433383 KDa
配列文字列: MAQNVYGPGV RMGNWNEDVY LEEERMRHFL EKREKGELLI QRNRRVKKNI LRPMQLSVSE DGYVHYGDKV IIVNPDQVLG EEAGKFMRG DLSLCMSPDE VKAQLSDDLE IPCGVSAVQT IAPMGRNTFT ILSDGANSCE MGQVVVYGQN FCLGIAAGLE G KMLYLTSD ...文字列:
MAQNVYGPGV RMGNWNEDVY LEEERMRHFL EKREKGELLI QRNRRVKKNI LRPMQLSVSE DGYVHYGDKV IIVNPDQVLG EEAGKFMRG DLSLCMSPDE VKAQLSDDLE IPCGVSAVQT IAPMGRNTFT ILSDGANSCE MGQVVVYGQN FCLGIAAGLE G KMLYLTSD HRTLLKSSLK SGLQEVTLTD EVTHLNCWQA AFLDPQLRLE YEGFPVRANE KIVIYHRHTN RALAVHRNLF LR TYFGKEM EVVAHTYLDS HKVEKPKNQW MLVTGNPRNK SNTMLDISKP ITEDTRALEQ AMGINT

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分子 #16: Piercer of microtubule wall 2 protein

分子名称: Piercer of microtubule wall 2 protein / タイプ: protein_or_peptide / ID: 16 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 13.728513 KDa
配列文字列:
MARETDCDLD KKTSLTSDAE MRPEPPALCV NPGNPVFSCM LDPKTLHTAT SLSKAQMIMY KTSASQYGAF SPRPFFFPCK FLPQEQAFT EHLKTTGFYQ NNSLNVGPDR TRTIDSPNYQ HTL

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分子 #17: Protein FAM166A

分子名称: Protein FAM166A / タイプ: protein_or_peptide / ID: 17 / コピー数: 16 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 36.659566 KDa
配列文字列: MTATQKHNLF TPEPHYIPGY AGFYPQLRYQ VGNTYGRTTA QLLTDPSVQK SPCSVLSPMT KPKFIEDFSK SKPPWIPCRD LREPYIPHY TSLKPYKNFE ILGQLPRQDV DTQGPPQVEN RQGPLTAGFM PYPPYPACPP GRKGEARDLG HPGLLLAYGE E AWKDAAPL ...文字列:
MTATQKHNLF TPEPHYIPGY AGFYPQLRYQ VGNTYGRTTA QLLTDPSVQK SPCSVLSPMT KPKFIEDFSK SKPPWIPCRD LREPYIPHY TSLKPYKNFE ILGQLPRQDV DTQGPPQVEN RQGPLTAGFM PYPPYPACPP GRKGEARDLG HPGLLLAYGE E AWKDAAPL QDTPGKNNQL YHCRRDEYLP PHPPQETLDV GRFQRLPQLD HPNLIQRKAI SGYAGFVPRF AWVMGMNYRD GV TQAMDDF DKNQFVFRHP VCALGERLPR THWPNTTIYR SQGLIPFYMG FIPSMQDNYA LTFGNSTRRA YQKELDRRSH TL

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分子 #18: Cilia- and flagella-associated protein 68

分子名称: Cilia- and flagella-associated protein 68 / タイプ: protein_or_peptide / ID: 18 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 19.552668 KDa
配列文字列:
MAVSCSLNHS TYLQRQNLVC YLRNPHYGSL IYADGHGEVW TDWNDMSKFL QYGWRCTTNE NSYSNRTLVG NWNQERYDLK NIVKPKPLP SQFGHAFETT YDANYSRKKP QSTHRFKREP HWFPGHQPEL DPPHYKCTAK STYMTNYSEP QPTHYSCCVY D PSVSQS

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分子 #19: Cilia and flagella-associated protein 77

分子名称: Cilia and flagella-associated protein 77 / タイプ: protein_or_peptide / ID: 19 / コピー数: 5 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 32.78602 KDa
配列文字列: MPDPAKPGKD LTAWKKKKQP VHRTVSQICP PPRRPLTVVD IRTGMENERL GVVRDSMFQN PLIVKAELGK PRERSCSLPG INFNYGLYI RGLDGGVPEA IGHWNVFKQQ PTCPHELTRN YIAMNRGAVK AGLVTARENM LYRELNDIRI NDQEDRRQKE P PPIPPNMT ...文字列:
MPDPAKPGKD LTAWKKKKQP VHRTVSQICP PPRRPLTVVD IRTGMENERL GVVRDSMFQN PLIVKAELGK PRERSCSLPG INFNYGLYI RGLDGGVPEA IGHWNVFKQQ PTCPHELTRN YIAMNRGAVK AGLVTARENM LYRELNDIRI NDQEDRRQKE P PPIPPNMT FGIRSRPSTP FFDLLQHRYQ QLWVQEQKAT QQAIKMEKKQ KVILGKLYET RSSQLRKYKP PVKLDALWHM PH FKKVASH LATFPTEADR QRALKAHKEE YAVRQGTLRM GNYTHP

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分子 #20: Family with sequence similarity 183, member B

分子名称: Family with sequence similarity 183, member B / タイプ: protein_or_peptide / ID: 20 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 16.357517 KDa
配列文字列:
MAMAGRVGQM KNQDEVHQNQ ILRELFLKEL RAQKLYTQYH VNPLRKVHTI TRKPMSWHDN LEEPEDAKFL NLIHHAAQGP KKKYSETQT EAQEIGWDPN PLINPDRQDH RLNHFRVYHD ITLYKAKLWS LGEDDHQK

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分子 #21: Cilia- and flagella-associated protein 90

分子名称: Cilia- and flagella-associated protein 90 / タイプ: protein_or_peptide / ID: 21 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 20.886428 KDa
配列文字列:
MEELAKKERR AMDPGGLKKE GKVEEEAGKE EGREEEGGEE EEVTSETLRG KPRPLPISAL PAFSYIPPRH QGPKERSYFS REGQTGIVS LYDCVFKRRL DYNQKLHRDD REHAKNLGLH INEEEQERTV PVLMSSVYGK RINQPIEPLN RDYGHVSHVK T DFYRKNEI PSIKGPGFGH INPA

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分子 #22: Protein FAM166C

分子名称: Protein FAM166C / タイプ: protein_or_peptide / ID: 22 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 23.097957 KDa
配列文字列: MAFRSAGTLM TEFNAAFVPP ALMPGYKGHV PGVASSFGSS YGNTTFKYFQ DLRNTGLEKS YALLSGGCFP TIFSPNSPLV LTDNSQNWD RWLHQPTYSR SNQDNGRTTE LTNFYKTVQQ QRKYYQDKTG ILSRVPYFVL PVKEPDRYPL PTDLPPLSEK S KWNLLRLS ...文字列:
MAFRSAGTLM TEFNAAFVPP ALMPGYKGHV PGVASSFGSS YGNTTFKYFQ DLRNTGLEKS YALLSGGCFP TIFSPNSPLV LTDNSQNWD RWLHQPTYSR SNQDNGRTTE LTNFYKTVQQ QRKYYQDKTG ILSRVPYFVL PVKEPDRYPL PTDLPPLSEK S KWNLLRLS PDYKRTYQTF PSGKRVSSQE RQRRDLYFEF RA

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分子 #23: RIB43A-like with coiled-coils protein 1

分子名称: RIB43A-like with coiled-coils protein 1 / タイプ: protein_or_peptide / ID: 23 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 45.03216 KDa
配列文字列: MYKLDLVSDP RELAAIEARR NREKERQSRF FNVRNRVMGV DVEALNYQVE ERKFREAIER NKDIAYGTKH AHYDLVAQML EKEEAERAY RLSKRVQDFR EQRQQQYKNG HEFDFWDPDQ FQEFRVPYYE KDAYFGPASM QYFFGEDLER ASHVRMQQEQ M RYNLEKQL ...文字列:
MYKLDLVSDP RELAAIEARR NREKERQSRF FNVRNRVMGV DVEALNYQVE ERKFREAIER NKDIAYGTKH AHYDLVAQML EKEEAERAY RLSKRVQDFR EQRQQQYKNG HEFDFWDPDQ FQEFRVPYYE KDAYFGPASM QYFFGEDLER ASHVRMQQEQ M RYNLEKQL QEQQAAREEE ARAALLSDQL RLAADTRAAE LARLEESCRA AMRTAMANAN KAQAAKQALQ QRREQQRQQE AN LTEVKKQ VTSDLLTENP QVAQRANAPH RVLPYCWKGM SAEQRAAIRK TQETQRQEKK EQRQAEKLVE AEWGRQNKRL AEA ALELEE QERELCAEFR RGLGSFNREL AKEQQAQQNY LNSVIYTNQP TAHYYLQFNT SSR

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分子 #24: Dual specificity phosphatase 21

分子名称: Dual specificity phosphatase 21 / タイプ: protein_or_peptide / ID: 24 / コピー数: 4 / 光学異性体: LEVO / EC番号: protein-serine/threonine phosphatase
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 21.527574 KDa
配列文字列: MTTASCIFPS QATQQDNIYG LSQITASLFI SNSAVANDKL TLSNNHITTI INVSAEVVNT FFEDIQYVQV PVSDAPNSYL YDFFDPIAD HIHGVEMRNG RTLLHCAAGV SRSATLCLAY LMKYHNMTLL DAHTWTKTCR PIIRPNNGFW EQLIHYEFKL F SRNTVRMI ...文字列:
MTTASCIFPS QATQQDNIYG LSQITASLFI SNSAVANDKL TLSNNHITTI INVSAEVVNT FFEDIQYVQV PVSDAPNSYL YDFFDPIAD HIHGVEMRNG RTLLHCAAGV SRSATLCLAY LMKYHNMTLL DAHTWTKTCR PIIRPNNGFW EQLIHYEFKL F SRNTVRMI YSPIGLIPNI YEKEAYLMEL M

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分子 #25: EF-hand domain-containing protein 1

分子名称: EF-hand domain-containing protein 1 / タイプ: protein_or_peptide / ID: 25 / コピー数: 5 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 75.235422 KDa
配列文字列: MGTNPVHGLP FLPGSSFTDS TKTAFHRSQT LNYRNGYAVV RRPTMGIGGD RLHYNQLSQA ELDELANKAP ILTYGPLKQA PLAEFVPAH VAFDKKVLKF SAYFQEDVPI SMEEHYRIRH VNIYYYLEDD SMSVIEPVVE NSGIPQGKLI KRQRFTKNDM G DHYHWKDL ...文字列:
MGTNPVHGLP FLPGSSFTDS TKTAFHRSQT LNYRNGYAVV RRPTMGIGGD RLHYNQLSQA ELDELANKAP ILTYGPLKQA PLAEFVPAH VAFDKKVLKF SAYFQEDVPI SMEEHYRIRH VNIYYYLEDD SMSVIEPVVE NSGIPQGKLI KRQRFTKNDM G DHYHWKDL NRGINLTVYG KTFRIVDCDR FTQDFLESQG IELNPSEKIP LDPYTQLRKE PVRKYVTPSD FDQLKQFLTF DK QVLRFYA IWDDTDSLFG ECRHYIIHYY LMDDTVEIRE VHERNNGRDP FPLLMNRQRM PKVLVENAKN FPKCVLEISD QEV LEWYTA KDFIVGKPLT ILGRTFFIYD CDPFTRQFYK DKFGMPDLPP VDVTKKEPPP VKQELPPYNG YGLIEDSAQN CFAL IPKAP RKDVVKMLMN DNKVLRYLAA LESPIPEDKD RRFVFSYFLA TDMISIFEPP VRNSGIIGGK FLGRTKVVKS FSPVD NPIY YSPSDFFIGA VIEVFGHRFV ILDTDEYVLK YMESNASQYS PEALASIQNR IQKPELPAPE LESKQATGEP MVQGTE ESK VQDLDALIDQ IHMHLKYNSY KENLRETFQM YDKDESGYVD RETFFKICET LNVPVDDSLI KELIRLCTHG EGRINYY NF VRAFSN

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分子 #26: Testis expressed 49

分子名称: Testis expressed 49 / タイプ: protein_or_peptide / ID: 26 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 15.528622 KDa
配列文字列:
MAFFNLYLLG YQHYFQSKKR NTAQETNQKD EVPTRLPPII SEDGNYSVHQ NSHERYQEAV RKVLLKTFPN QVFRVPVTDA QNFSFWRSN IPGVRPEKAI PWIKTPHHCL IKSPMTRFVD HSHLNDKTFS LY

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分子 #27: Testis-expressed sequence 37 protein

分子名称: Testis-expressed sequence 37 protein / タイプ: protein_or_peptide / ID: 27 / コピー数: 5 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 21.069139 KDa
配列文字列:
MARVVRPQKN HVDLDIYQSS YMVDYKPFGK YKYSRVTPQE QAKLDAQLQS KEFYQPKPNP NPKLEEGYPA FRRPYMTALD LGVPGFFPP QERVTTRKDD GRFTTTCHYA YPASLALYLA QQDPYWLHQR ADFPCLMEPE RQPAPEVGKG YLLLPGCLCD H HQRVKVPI LNRWGPLMPF YQ

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分子 #28: Tektin bundle-interacting protein 1

分子名称: Tektin bundle-interacting protein 1 / タイプ: protein_or_peptide / ID: 28 / コピー数: 5 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 23.987262 KDa
配列文字列: MENVRREATR PSVPSGTLEL YFPDHLYRND YVSLEGPRWA PAIKQAVRWK FTPMGRDAAG QVWFTGLTNS EPGDAWYKLP RALDTPYRE AHTRWHGCFQ SRQRGLPPAY TQHLREMAFW DPAITAQYLN SGPRWGCMQW RDRQIRGKEF VVTRNQFGAK L PWRSDYVP ...文字列:
MENVRREATR PSVPSGTLEL YFPDHLYRND YVSLEGPRWA PAIKQAVRWK FTPMGRDAAG QVWFTGLTNS EPGDAWYKLP RALDTPYRE AHTRWHGCFQ SRQRGLPPAY TQHLREMAFW DPAITAQYLN SGPRWGCMQW RDRQIRGKEF VVTRNQFGAK L PWRSDYVP LLSLPQRPRF TAQDFRQRGL QRPCPAIGQP PPAFTPAL

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分子 #29: RIB43A-like with coiled-coils protein 2

分子名称: RIB43A-like with coiled-coils protein 2 / タイプ: protein_or_peptide / ID: 29 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 45.328156 KDa
配列文字列: MEVAMSKDLQ QEANLAKKRY IDLCRQGRIF DARNRIIGGD TQAWDFQVRD QKIKEITDKA RHEAFAAEMK HNDKVMCMAH DREQRHRKQ LCRAINDFQQ NFQKPETRRE FDLSDPLALQ KELPARISDN DMRNTISGMQ KFMGEDLNFQ ERRRFQKEQS R EWFLQQHG ...文字列:
MEVAMSKDLQ QEANLAKKRY IDLCRQGRIF DARNRIIGGD TQAWDFQVRD QKIKEITDKA RHEAFAAEMK HNDKVMCMAH DREQRHRKQ LCRAINDFQQ NFQKPETRRE FDLSDPLALQ KELPARISDN DMRNTISGMQ KFMGEDLNFQ ERRRFQKEQS R EWFLQQHG EREKARADHL LAEHLHTQTR LKFDETAREL MKLEGSTRKE VCAAVKAFNK NQVVELTERK RQEKQQEQED NM TEITNLL HGDLLSENPR PVASSFGSHR VVLDRWKGMN REQLEEIWFT QKRQIQEKLR LQEEERQHSM DWDLRRIRKA HAS LLHERQ QQRLLREQRR ALDCSNLNLA RQQYLQKKQM NTASSSQPTE DYFSQFNTRS R

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分子 #30: Tektin-5

分子名称: Tektin-5 / タイプ: protein_or_peptide / ID: 30 / コピー数: 26 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 62.817535 KDa
配列文字列: MEFLGTTQTA SFCGPKKGCG LQALPPAGQE PVVQECYQPF HLPGYRYLNA WRPSVFHKIA TSQTIPEECS GIRRPPTILP SLRSALFCR YTPRDWDRSN DLQIRNAEAS RLWASRLTGD SLRIMQDKDQ LIHQMQEGTS RNLGQRLSDL GFWKSELCYE L DRLLTENS ...文字列:
MEFLGTTQTA SFCGPKKGCG LQALPPAGQE PVVQECYQPF HLPGYRYLNA WRPSVFHKIA TSQTIPEECS GIRRPPTILP SLRSALFCR YTPRDWDRSN DLQIRNAEAS RLWASRLTGD SLRIMQDKDQ LIHQMQEGTS RNLGQRLSDL GFWKSELCYE L DRLLTENS SMDTLKRRLE CAAEEVNCPL QVALECLYNR EKRIGIDLVH DNVEKNLIRE VDLLKCCQDQ MRKLAKRIDF QI RDNRDAQ HSLERDIEDK SSAQYIDENC FNLRSTSDSI SFFHGVEKFD GTVSIPETWA KFSNDNIRHA QNMRANSIRL REE AEHLFE TLSDQMWKQF TNTNLAFNAR ISEETDVKNK LQTQLAKILQ EIFQAENTIM LLERAIVAKE YPLKMAQTML ACRT RRPNV ELCRDVPQFR LVNEVFTIDD TLQTLKLRLR ETQDTLQLLV MTKSRLEHEL AIKANTLCID KDKCMSMRKS FPSTP RLTG YTCSAIGSGP YANHAPRISS GPCSGSALCK GPASCGGGAS CGGGASCGGH APCGSALCSH SVSRSGPGFA PVC

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分子 #31: EF-hand domain-containing family member C2

分子名称: EF-hand domain-containing family member C2 / タイプ: protein_or_peptide / ID: 31 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 87.758023 KDa
配列文字列: MALPFLPGNS FNRNIGKERF HKSQHWGFCN NVRMLVSENK PGVGGDLLYG QKIKPKHSVF PKGDGTDAPS WVAFDKQVLS FDAYLEDEI SDKRQEIFRI RYYKIYFYLE DDTIQVNEPE VINSGLPQGT SIRRQRIPYP PPNDDQFYTV YDFNINISVV F YGRTFKIY ...文字列:
MALPFLPGNS FNRNIGKERF HKSQHWGFCN NVRMLVSENK PGVGGDLLYG QKIKPKHSVF PKGDGTDAPS WVAFDKQVLS FDAYLEDEI SDKRQEIFRI RYYKIYFYLE DDTIQVNEPE VINSGLPQGT SIRRQRIPYP PPNDDQFYTV YDFNINISVV F YGRTFKIY DCDPFTKNFL KKIGIKLNPP GQCPLDPYMK MRRETLEFVD PFRPYQSFDT LKRFIQYDGK VLRFFCLWDD ST SLFGDRR EFVLHYFLCD GTVEIREVLP SNSGRDAMSS FLRRGKLPKY GPPGIYQPGQ ITDRAVLNVY GGLSEWRADG YLL DKYQLG KVEQDFYTDQ DLSIGATINV WGRKVLLCDC DEFTKTYYRT KYGVDNFTPI SCKPPHLPKI ERKYPPYTGF GSEE DSFRS CVGLKPTPHR KNFKKFMELD SFGNISNILR YFGKLITHKC ADVDRIFVIA FYLSDDTISV FEPIENNSGN AGGMF LKRS RVKKPGQEVF KSEFSEYIKA EELYIGATVN INGYLFILLN ADEYTLNYME NNTDKFPYSN FELAIQKLKQ EKSKSR EIT QVFAAADYNH TKVVPYNTFR DILMSITMGK LIDQELITIA RHYRVPEIMD PDLAYLIARA HEKFKKNIFE NFDMFIY NC VYEDREKKGV LPTKDIRRMC KSSRLPLDDD FLDCLLSRFE DKDHQINYEI FFSVLNWRMN PTPDLQAPPY LKEKCEDV W VGMPSPIPVK YVRYLDFLID VYGLEDNML

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分子 #32: Spermatid-specific manchette-related protein 1

分子名称: Spermatid-specific manchette-related protein 1 / タイプ: protein_or_peptide / ID: 32 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 29.977191 KDa
配列文字列: MFLFSRKTKT PISTYSDSYR APTSIKEVYK DPPLWAWEAN KFVTPGLTQT MHRHVDPEAL QKMTKCAAQD YTYKSSISGH PYLPEKYWL SPDEEDKCCP SYLDNDRYNT WKTSPCSNYW NKYTGCLPRL SKDTGMESVR GMPLEYPPKQ ERLNAYEREV V VNMLNSLS ...文字列:
MFLFSRKTKT PISTYSDSYR APTSIKEVYK DPPLWAWEAN KFVTPGLTQT MHRHVDPEAL QKMTKCAAQD YTYKSSISGH PYLPEKYWL SPDEEDKCCP SYLDNDRYNT WKTSPCSNYW NKYTGCLPRL SKDTGMESVR GMPLEYPPKQ ERLNAYEREV V VNMLNSLS RNRTLPQIVP RCGCVDPLPG RLPYQGYESP CSGRHYCLRG MDYCTTREPS TERRLRPLCS QQPTECVALR SP ARNAMCC YNSPAIILPV SQP

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分子 #33: Protein phosphatase 1 regulatory subunit 32

分子名称: Protein phosphatase 1 regulatory subunit 32 / タイプ: protein_or_peptide / ID: 33 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 47.873078 KDa
配列文字列: MMGKLPLGVV SPYVKMSSGG CSDPLKFYAT SYCTAYGREE FKPRLGSHVG TGYKSNYRPL VSYQPHLDTL DNPAIGQQIR DTSKSVTSQ SYSPLEVPDG KQPLPWNLHQ TTSSYGREKL NPGPHSKEVR KVHFDTQDHG PQTITGLEPK EVPLIHQQQG K GSTEWENS ...文字列:
MMGKLPLGVV SPYVKMSSGG CSDPLKFYAT SYCTAYGREE FKPRLGSHVG TGYKSNYRPL VSYQPHLDTL DNPAIGQQIR DTSKSVTSQ SYSPLEVPDG KQPLPWNLHQ TTSSYGREKL NPGPHSKEVR KVHFDTQDHG PQTITGLEPK EVPLIHQQQG K GSTEWENS HYGPRFMTSE YNSKYIKESP NHPDLLLKKT IGSKEETGFT EESTKNPIVF QPPSQAFPGD PVLHPGRSIT KS DYLPVTH PQGSDFLPVL SRGSDRDTGF SRVNERTLNP RVPTPAPQPA SMSHRSYQPP QRMQQTNVAL LGRESVGNKE PTG FTLNNP SYVRSSYEQD RDQRYLTTYN QGYFENIPKG LDREGWTRGG IQPQKAGAYA LSELNNHTLM DSTPNPTETL RHLH PHVGR TLASVDPFYR DMPHSSRYPA SS

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分子 #34: Testis-specific serine/threonine-protein kinase 6

分子名称: Testis-specific serine/threonine-protein kinase 6 / タイプ: protein_or_peptide / ID: 34 / コピー数: 3 / 光学異性体: LEVO / EC番号: non-specific serine/threonine protein kinase
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 30.332943 KDa
配列文字列: MSGDKLLSEL GYKLGRTIGE GSYSKVKVAT SKKYKGTVAI KVVDRRRAPP DFVNKFLPRE LSILRGVRHP HIVHVFEFIE VCNGKLYIV MEAAATDLLQ AVQRNGRIPG SQARELFSQI AGAVRYLHDH HLVHRDLKCE NVLLSPDERR VKITDFGFGR Q AHGYPDLS ...文字列:
MSGDKLLSEL GYKLGRTIGE GSYSKVKVAT SKKYKGTVAI KVVDRRRAPP DFVNKFLPRE LSILRGVRHP HIVHVFEFIE VCNGKLYIV MEAAATDLLQ AVQRNGRIPG SQARELFSQI AGAVRYLHDH HLVHRDLKCE NVLLSPDERR VKITDFGFGR Q AHGYPDLS TTYCGSAAYA SPEVLLGIPY DPKKYDVWSL GVVLYVMVTG CMPFDDSDIA GLPRRQKRGV LYPDGLELSE RC KSLIAEL LQFSPSARPS AGQVARNGWL RAGDSG

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分子 #35: Cilia- and flagella-associated protein 20

分子名称: Cilia- and flagella-associated protein 20 / タイプ: protein_or_peptide / ID: 35 / コピー数: 8 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 22.781389 KDa
配列文字列: MFKNTFQSGF LSILYSIGSK PLQIWDKKVR NGHIKRITDN DIQSLVLEIE GTNVSTTYIT CPADPKKTLG IKLPFLVMII KNLKKYFTF EVQVLDDKNV RRRFRASNYQ STTRVKPFIC TMPMRLDDGW NQIQFNLSDF TRRAYGTNYI ETLRVQIHAN C RIRRVYFS ...文字列:
MFKNTFQSGF LSILYSIGSK PLQIWDKKVR NGHIKRITDN DIQSLVLEIE GTNVSTTYIT CPADPKKTLG IKLPFLVMII KNLKKYFTF EVQVLDDKNV RRRFRASNYQ STTRVKPFIC TMPMRLDDGW NQIQFNLSDF TRRAYGTNYI ETLRVQIHAN C RIRRVYFS DRLYSEDELP AEFKLYLPVQ NKAKQ

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分子 #36: Outer dense fiber protein 3

分子名称: Outer dense fiber protein 3 / タイプ: protein_or_peptide / ID: 36 / コピー数: 6 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 27.690973 KDa
配列文字列: MAEEVWMGTW RPHRPRGPIM ALYSSPGPKY LIPPTTGFVK HTPTKLRAPA YSFRGAPMLL AENCSPGPRY SVNPKILKTG KDLGPAYSI LGRYHTKTLL TPGPGDYFPE KSTKYVFDSA PSHSISARTK TFRVDSTPGP AAYMLPVVMG PHTVGKVSQP S FSIKGRSK ...文字列:
MAEEVWMGTW RPHRPRGPIM ALYSSPGPKY LIPPTTGFVK HTPTKLRAPA YSFRGAPMLL AENCSPGPRY SVNPKILKTG KDLGPAYSI LGRYHTKTLL TPGPGDYFPE KSTKYVFDSA PSHSISARTK TFRVDSTPGP AAYMLPVVMG PHTVGKVSQP S FSIKGRSK LGSFSDDLHK TPGPAAYRQT EVQVTKFKAP QYTMAARVEP PGDKTLKPGP GAHSPEKVTL NKPCAPTVTF GI KHSDYMT PLVVDVE

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分子 #37: Parkin coregulated gene protein homolog

分子名称: Parkin coregulated gene protein homolog / タイプ: protein_or_peptide / ID: 37 / コピー数: 8 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 27.763268 KDa
配列文字列: MPKRTKLLPQ QTFQVHQPRS LVSEGFTVKA MMKNSVVRGP PVAGAFKERP AKPTTFRKCY ERGDFPIALE HDSKGNKIAW KVEIEKLDY HHYLPLFFDG LSEMTFPYEF FARRGIHDML EHGGNKILPV IPQLIIPIKN ALNLRNRQII CVTLKVLQHL V VSSEMVGE ...文字列:
MPKRTKLLPQ QTFQVHQPRS LVSEGFTVKA MMKNSVVRGP PVAGAFKERP AKPTTFRKCY ERGDFPIALE HDSKGNKIAW KVEIEKLDY HHYLPLFFDG LSEMTFPYEF FARRGIHDML EHGGNKILPV IPQLIIPIKN ALNLRNRQII CVTLKVLQHL V VSSEMVGE ALLPYYRQIL PILNIFKNMN VNSGDGIDYS QQKRENIGDL IQETLEAFER YGGEDAFINI KYMVPTYESC LL N

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分子 #38: Testis, prostate and placenta-expressed protein

分子名称: Testis, prostate and placenta-expressed protein / タイプ: protein_or_peptide / ID: 38 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 24.985697 KDa
配列文字列: MAQIIDLVPW DECSAHLYAS PAVLLPLERV RHPLAGVKHQ LYHPALPSLR RMDMDTVKGC LSDEHCQSST YFSKDDFNKA HFTLLGVPN KPLQCLDFTA TGQKLCHKYR GGKMIPIAPG INRVDWPCFT RAIEDWSKFV SRSEEFKLPC ANKRVEGFSG Y AVRYLKPE ...文字列:
MAQIIDLVPW DECSAHLYAS PAVLLPLERV RHPLAGVKHQ LYHPALPSLR RMDMDTVKGC LSDEHCQSST YFSKDDFNKA HFTLLGVPN KPLQCLDFTA TGQKLCHKYR GGKMIPIAPG INRVDWPCFT RAIEDWSKFV SRSEEFKLPC ANKRVEGFSG Y AVRYLKPE VTQNWRYCLN QNPSLDRYGQ KPLPFDSLNA FRRFGSHYSR INYLTPWH

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分子 #39: Cilia- and flagella-associated protein 45

分子名称: Cilia- and flagella-associated protein 45 / タイプ: protein_or_peptide / ID: 39 / コピー数: 5 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 65.962016 KDa
配列文字列: MPLRPGDASS SASTASNRSR TRTRYRTKAM NSEVDESLFG GVKPSSQGKS DSPIVVIHDK HAIRKTLSAL GLEHKTETIQ LITRDMVRE LIVPTEDPSG ESLIISPEEF ERIKWASQVL TKEELNAREQ ALKKEKEGIL EAVTIRKKIM KQKEMTWNNN K KLSDLEEV ...文字列:
MPLRPGDASS SASTASNRSR TRTRYRTKAM NSEVDESLFG GVKPSSQGKS DSPIVVIHDK HAIRKTLSAL GLEHKTETIQ LITRDMVRE LIVPTEDPSG ESLIISPEEF ERIKWASQVL TKEELNAREQ ALKKEKEGIL EAVTIRKKIM KQKEMTWNNN K KLSDLEEV ARERAQNLLQ RADKLRMEQE EELKDMSKII LNAKCHAIRD AQILEKQQIQ KELDEEERRL DHMMEIDRRE SL QRQEDRE RKRREERVRG KRHIVEQIKK NEEERSLQAE HREQEKEQML AYLDRLQEED LQDLERRHQE KLKMQAEIKR IND ENQRQK AEMLAQERLA DQMVMEFTKK KMAREAEYEA EQEKIRREKE KEIARLRALQ EKAQDYQAEQ DALRAKRNQE VADR EWRRK EKENAQKKIE TEEKLRKSRL EQVAFKEHTL AVQVQRDRDE FERILRAQRE QIEREKQEQE KKAKGCLQHA NELRR QVRE NQQKHVQNRL ATFEEGRRLK EEAEKRRERI EDIKKQKLEE LRATGLPEKY CIEVERKANI LPATSVN

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分子 #40: Uncharacterized protein C10orf82 homolog

分子名称: Uncharacterized protein C10orf82 homolog / タイプ: protein_or_peptide / ID: 40 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 25.847469 KDa
配列文字列: MESPKTFMRK LPITPGYCGF IPWLSCQESS SEDRMNPCVK AFQERTQRYK EDQQGLNCSV ANTPPLKPIC SEDTVLWVLH EYAKKYHPL TLECKNEKKP LQEPPIPGWA GYLPRARVTE FGYATRYTIM AKKCYKDFLD LVEQAKRAQL KPYEQTYDVR A AQPLSPSS ...文字列:
MESPKTFMRK LPITPGYCGF IPWLSCQESS SEDRMNPCVK AFQERTQRYK EDQQGLNCSV ANTPPLKPIC SEDTVLWVLH EYAKKYHPL TLECKNEKKP LQEPPIPGWA GYLPRARVTE FGYATRYTIM AKKCYKDFLD LVEQAKRAQL KPYEQTYDVR A AQPLSPSS KILQLQGLSP AFPEFSGPGQ TPPSEDPQAP RPCGCAQWSS QSCSRNVYGE PPSLAKAFAE S

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分子 #41: Coiled-coil domain-containing protein 105

分子名称: Coiled-coil domain-containing protein 105 / タイプ: protein_or_peptide / ID: 41 / コピー数: 5 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 57.406484 KDa
配列文字列: MPVLLPSTDP GQDSRVGAPE WRQAAKATSR KAHLLTDRCG QEAVTMWQPK DSVLDPNVAH HLGRAAYMEP WRFRVEMLKG GGTLEKPPP GEGVTLWKGK MKPPAWYARL PLPMHRDARA QQTAEVVHAH ARGARLTAAR LGRAQHQING QLRLLLRQRE A TDRRLSEV ...文字列:
MPVLLPSTDP GQDSRVGAPE WRQAAKATSR KAHLLTDRCG QEAVTMWQPK DSVLDPNVAH HLGRAAYMEP WRFRVEMLKG GGTLEKPPP GEGVTLWKGK MKPPAWYARL PLPMHRDARA QQTAEVVHAH ARGARLTAAR LGRAQHQING QLRLLLRQRE A TDRRLSEV RKGLLINQQS VKLRGYRPKC EKIPDKADSL LVWEKKELKS MKRKMEKDME ISEDLLKALA SCRDTLDFYC QE RLQAVEL MNQPLDKVLE QAGRHSWVDI TRPPTPRTQG LKTPPPDPIG TYTPACAKAL FEAKRLLMES KDILTEMAKN EVD IQNQQQ EISNRVCSSL AQKMRETLEL KERMTMTLGL MRGTIHRCMK FNQEMYVTRG IIKGPLLKRN LEAREKLNRP LVRM YQRHV GTQLPEATRL AQGTDLLTRH NLHMEKNLKE LRTTHDNLAW GLNCKKIGHD VDYDVVRLRL RQRHPHVCYE QAQRL VNDW DPPTPARSQT NTASK

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分子 #42: Cilia- and flagella-associated protein 52

分子名称: Cilia- and flagella-associated protein 52 / タイプ: protein_or_peptide / ID: 42 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 68.322164 KDa
配列文字列: MEEQVLPELD VAELELQAVI GFNGHVPNGL KCHPDQEHLI YPLGCTVLIQ AINTNEQNFL HGHGNNVSCV TISKEGDYIA SGQVTFMGF KADIILWDFK KRELIARLSL HKGKIEALAF SPNDLYLVSL GGPDDGSVVV WSIAKRDAIC GSPAAGLNVG N ATSVVFSR ...文字列:
MEEQVLPELD VAELELQAVI GFNGHVPNGL KCHPDQEHLI YPLGCTVLIQ AINTNEQNFL HGHGNNVSCV TISKEGDYIA SGQVTFMGF KADIILWDFK KRELIARLSL HKGKIEALAF SPNDLYLVSL GGPDDGSVVV WSIAKRDAIC GSPAAGLNVG N ATSVVFSR CRDEMFVTAG NGTIRVWELD LPNRKIWPTE CQTGQMKRIV LSTGMADDDS FFYLGTTTGD ILKMNPKTKL LA DTGPVKD KFSLGVSALR CLKMGGLLVG SGAGLLIFCK SPSYKPIKKV QLQGGITSIT LRGEGHQFFV GTEESHIYRV NFT DFKETL IATCHFEAVQ DIVFPFGTAE LFATCAKKDI RVWHTMSKRE LLRITVPNMT CHGIDFMRDG KSIISAWDDG KIRA FAPES GRLMYTINSA HRIGVTAIAT TSDCKRIISG GGEGEVRVWQ VGCQTQKLEE ALKEHKSSVS CIRVKKNNEE CVTAS TDGT CIIWDLVRLR RNQMILANTL FQCVCYHPEE FQIITSGTDR KIAYWEVFDG SVIRELEGSL SGSINGMDIT QEGGHF VTG GHDHLVKVWD YNEGEVTHVG VGHSGNIMAM RISPGNQYIV SVSADGAILR WKYPFAS

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分子 #43: Enkurin

分子名称: Enkurin / タイプ: protein_or_peptide / ID: 43 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 29.587521 KDa
配列文字列: MDSPCTSESI YNLIPSDLKE PPQHPRYTSL FRATIKNDMK KFKTAMKTMG PAKVEIPSPK DFLKKHSKEK TLPPKKKFNR CSPKKPAVP LRTDHPVMGI QSGKNFINTN AADVIMGVAK KPKPIYVDKR TGDKHDLETS GLFPKYINKK DYGITPEYIC K RNEDVKKA ...文字列:
MDSPCTSESI YNLIPSDLKE PPQHPRYTSL FRATIKNDMK KFKTAMKTMG PAKVEIPSPK DFLKKHSKEK TLPPKKKFNR CSPKKPAVP LRTDHPVMGI QSGKNFINTN AADVIMGVAK KPKPIYVDKR TGDKHDLETS GLFPKYINKK DYGITPEYIC K RNEDVKKA QEEYDNYIQE NLKKAAMKRL SDEEREAVLQ GLKKNWEEVH KEFQSLSVFI DSVPKKIRKQ KLEKEMKQLE HD ISVIEKH KIIYIANK

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分子 #44: Testis-expressed protein 43

分子名称: Testis-expressed protein 43 / タイプ: protein_or_peptide / ID: 44 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 16.305608 KDa
配列文字列:
MASEKDDGPA LPKLDDDNQT AENTCKPAEE QPQQLRWDDI HLPRFSLKQG MIPTRYVMPW KENMKFRNVN LQQAEACGIY AGPLEDSLF WGYSERLCHG EDRKAVLKKG LPEIKITDMP LHSPLSRYQS TVISHGFRRR LI

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分子 #45: Protein Flattop

分子名称: Protein Flattop / タイプ: protein_or_peptide / ID: 45 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 20.575123 KDa
配列文字列: MATNYSANQY EKAYLPTYLQ NWSPARPTKE KIAAHEGYTQ IIANDRGHLL PSVPRSKASP WGSFMGTWQM PLKIPPAKVT LTARTTTAA DNLTKWIHKN PDLLNACNGL RPEISGKPFD PDSQTKQKKS VTKTVQQAPN PTIIPSSPVI QGDNPDEPQS S HPSAGHTP ...文字列:
MATNYSANQY EKAYLPTYLQ NWSPARPTKE KIAAHEGYTQ IIANDRGHLL PSVPRSKASP WGSFMGTWQM PLKIPPAKVT LTARTTTAA DNLTKWIHKN PDLLNACNGL RPEISGKPFD PDSQTKQKKS VTKTVQQAPN PTIIPSSPVI QGDNPDEPQS S HPSAGHTP GPQTPVNSPN NPPPSPCKST K

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分子 #46: EF-hand calcium-binding domain-containing protein 6

分子名称: EF-hand calcium-binding domain-containing protein 6 / タイプ: protein_or_peptide / ID: 46 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 176.028312 KDa
配列文字列: MKRNGTRLNF AKANSTKSGS TRARDLMNKM SIIPEWHSLY SNTRKLPCSR PHSSPCKMQR TIFQDLCRPS SSTTAIANPV LSYLDIERI LAQKISSRRD DIKKVFQILD RNHNQMVTKG DLKRVITAFL IPLTKDQFQD LLAQIPISSL GNVPYLEFLS R FGGGIDIN ...文字列:
MKRNGTRLNF AKANSTKSGS TRARDLMNKM SIIPEWHSLY SNTRKLPCSR PHSSPCKMQR TIFQDLCRPS SSTTAIANPV LSYLDIERI LAQKISSRRD DIKKVFQILD RNHNQMVTKG DLKRVITAFL IPLTKDQFQD LLAQIPISSL GNVPYLEFLS R FGGGIDIN INGIKRVNEN EVDNRRTVKE VQLTEKIFRN MRSIRKVFQV MDVNNTGLVQ PQELRRVLET FCLRMQDGDY EK FLEQYNI DKTTAVDYNA FLKNLSVKND ASFKYLLSNA AELSRETQQG KNGKRLLDTG SSEDVWKNYS LDDLEKTFCQ EFS KSYEKI EKALSAGDPS KGGYISLNYL KVVLDTFIYR LPRRIFIQLI RRFGLKTSTK INWKQFLTAI YERQKLEVSK TLPL KKRSS TEARNRSRKE NIIKKLFKYS EDRYTALKKT LLIISSTPSG HITWEELRHI LNCMVAKLND SEFSELKQTF DPEGT GAVR VNSLLDVLDD STKVRKMSPS TDTKTPLPVA WDSVEELVLD SITRNLQAFY SMLQSYDLRD TGTIGKNNFR KVMRVF CPY LSNEHLVRFS SKFQEAGSGR ILYKKFLLSI GVGIPPPTPP LSSPKVQLSD QFQIEEPGQQ DERTQPSGEK TSEINNM TK EEVIDGLKHR IQQKDPVFRK QFLSISKEPD VKINQEEFRK VLERSGMPMN DCQYAMLASK LGFKNEEGMS YQDFTMGF E DCMLSGLETV PLQSRTASRT NMDEHFISAE ECLRIFPKKL KESFRDVYSA FFRIDLDRDG IISMHDFHRL LQYLQLNMV DLEFERFLSL LGLRLSVTLN FREFQNLCEK RPWKSDEAPQ RLIRCKQKVA DSELACEQAH QYLIMKAKTR WADLSKNFIE TDNEGNGIL RRRDIKNSLY GFDIPLTPRE FEKLWQNYDT EGRGYITYQE FLHRLGIRYS PKVHRPYKED YFNFLGHFTK P KQVQEEIQ ELQQISEREK LMNHYEEISK AFNAMEKSKP VALCRVQKVL QECGCPLKEE ELISLLKSLD VSVHNNHIDP VE FLRALEI SWASKARPKE KEESSPPPIS FSKVTPDEVI KTMQEVVESS QPALVEAFSA LDKEDTGFVK AMEFGDVLRS VCQ KLTDNQ YHYFLRRLRL HLTPNIHWKY FLENFSTFQD ETADDWAENM PKAPPPMSPK ETAHRDIVAR VQKAVASHYH TIVQ EFENF DTLKSNTVSR DEFRSICTRH IQILTDEQFD RLWSELPVNA KGRLKYQDFL SKLSIERVPS PPMAAGDSGE STMAQ RGSS APEFSQGTRS NLYSPPRDSR VGLKSRSHPC TPVGTPPLQN CEPIESRLRK QIQGCWRELL RECKEKDTDK QGTISA AEF LALVEKFKLD ISREESQQLI VKYDLKNNGK FAYCDFIQSC VLLLKAKETS LMRRMRIQNA DKMKEAGMET PSFYSAL LR IQPKIVHCWR PMRRSFKTYD KNGTGLLSVA DFRKVLRQYS INLSEEEFFH VLEYYDKSLS SKISYNDFLR AFLQ

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分子 #47: Cilia- and flagella-associated protein 210

分子名称: Cilia- and flagella-associated protein 210 / タイプ: protein_or_peptide / ID: 47 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 65.26652 KDa
配列文字列: MQVRFGRRSG QAKESQGMDC FEKEEIPYPP LLPSKVDLQQ ITIIPHAEWE RIRDSLNRLT REAAVLRAER AAKKKMHVKS QELVKHWTN TYAGMKEQKL KAKQKRDEEI EAERKVLDLE EEIYKEGERK KAIESARQCQ FHQTERVKRF HSGLLLSRVM K ERDVQIQY ...文字列:
MQVRFGRRSG QAKESQGMDC FEKEEIPYPP LLPSKVDLQQ ITIIPHAEWE RIRDSLNRLT REAAVLRAER AAKKKMHVKS QELVKHWTN TYAGMKEQKL KAKQKRDEEI EAERKVLDLE EEIYKEGERK KAIESARQCQ FHQTERVKRF HSGLLLSRVM K ERDVQIQY KKNAVKSDKK WEEQVKLNDE KAFKEDQEKE EKRRRERVAL AEDHLKQIEE HKEEEEARKK SEEKDAEEMK RQ NLLYEIE MKKNLSKKQE EIDTNRKLLL DNMHNKNIIR AVEQQQQEEE DEKIRKFIKA KKRLIQMRMD KDAETHRLME ERR ERINNF LSKLIKEKLD TEDLIIARDI SEADAELEKR EKEKHEKNQA DLKAIAEYRA SVMKNKEEEE RQRKIEAKEQ LQAV LKADK IFQELEKEKS LKVTREKLEI QDAHIQQIAI NKYNAKQMKE EELDYWRLTD ALTVEKEKEF EKYAREVINF ESEST KKYA YPMVKAVQEG VGGGRGPPFV GRGGIRPSYQ ATDATGVQLP CFKSQGSKYN DFQKSKRRLG FTW

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分子 #48: Cilia- and flagella-associated protein 276

分子名称: Cilia- and flagella-associated protein 276 / タイプ: protein_or_peptide / ID: 48 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 18.960092 KDa
配列文字列:
MLQPQETFSN PALRDEDKHL GNLWASKKSL YKNPAHLAQQ QDPWSRLSST PTATSRSRDT FFDSKIPKDD LDFRLATLYN HHTGAFKNK TEILLHQETI EDIQGTKIQF PGECFHAPSA PITSRTTIRH WINPKKESIH SIQGSIVSPH TAATNGGYSR K NDGGFFST

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分子 #49: Piercer of microtubule wall 1 protein

分子名称: Piercer of microtubule wall 1 protein / タイプ: protein_or_peptide / ID: 49 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: house mouse (ハツカネズミ)
分子量理論値: 18.862852 KDa
配列文字列:
MSEEKPQQSA EEPEPGEPKA KPAPEEPEPG EPKAKPAPEE PEPGEPKAKP APEKTSDYYR ISEKLPVRFN NPGWFHGYGT KEAVSMYRT SNQTYGSRAP TVHEMPKVFY PSSNKFSRQH AAFGMFQSHN INVTLEKSLV TGPDNHITHY DRLNFHPSYN V NRPSICD

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分子 #50: GUANOSINE-5'-TRIPHOSPHATE

分子名称: GUANOSINE-5'-TRIPHOSPHATE / タイプ: ligand / ID: 50 / コピー数: 178 / 式: GTP
分子量理論値: 523.18 Da
Chemical component information

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP / GTP, エネルギー貯蔵分子*YM / グアノシン三リン酸

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分子 #51: MAGNESIUM ION

分子名称: MAGNESIUM ION / タイプ: ligand / ID: 51 / コピー数: 178 / 式: MG
分子量理論値: 24.305 Da

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分子 #52: GUANOSINE-5'-DIPHOSPHATE

分子名称: GUANOSINE-5'-DIPHOSPHATE / タイプ: ligand / ID: 52 / コピー数: 176 / 式: GDP
分子量理論値: 443.201 Da
Chemical component information

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP / GDP, エネルギー貯蔵分子*YM / グアノシン二リン酸

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実験情報

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構造解析

手法クライオ電子顕微鏡法
解析単粒子再構成法
試料の集合状態filament

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試料調製

緩衝液pH: 7.5
凍結凍結剤: ETHANE / 装置: FEI VITROBOT MARK IV

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電子顕微鏡法

顕微鏡FEI TITAN KRIOS
電子線加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
電子光学系照射モード: FLOOD BEAM / 撮影モード: BRIGHT FIELDBright-field microscopy / 最大 デフォーカス（公称値）: 2.6 µm / 最小 デフォーカス（公称値）: 1.5 µm / 倍率（公称値）: 81000
試料ステージ試料ホルダーモデル: FEI TITAN KRIOS AUTOGRID HOLDER
撮影フィルム・検出器のモデル: GATAN K3 (6k x 4k) / 実像数: 25135 / 平均露光時間: 2.56 sec. / 平均電子線量: 50.0 e/Å2
実験機器
モデル: Titan Krios / 画像提供: FEI Company

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画像解析

初期モデルモデルのタイプ: EMDB MAP
EMDB ID:

24664

初期 角度割当タイプ: NOT APPLICABLE
最終 角度割当タイプ: NOT APPLICABLE
最終 再構成解像度のタイプ: BY AUTHOR / 解像度: 3.5 Å / 解像度の算出法: FSC 0.143 CUT-OFF / 使用した粒子像数: 95290

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る