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-Structure paper
Title | Homoharringtonine as a PHGDH inhibitor: Unraveling metabolic dependencies and developing a potent therapeutic strategy for high-risk neuroblastoma. |
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Journal, issue, pages | Biomed Pharmacother, Vol. 166, Page 115429-115429, Year 2023 |
Publish date | May 25, 2021 (structure data deposition date) |
Authors | Hsieh, C.H. / Huang, C.T. / Cheng, Y.S. / Hsu, C.H. / Hsu, W.M. / Chung, Y.H. / Liu, Y.L. / Yang, T.S. / Chien, C.Y. / Lee, Y.H. ...Hsieh, C.H. / Huang, C.T. / Cheng, Y.S. / Hsu, C.H. / Hsu, W.M. / Chung, Y.H. / Liu, Y.L. / Yang, T.S. / Chien, C.Y. / Lee, Y.H. / Huang, H.C. / Juan, H.F. |
External links | Biomed Pharmacother / PubMed:37673018 |
Methods | X-ray diffraction |
Resolution | 2.99 Å |
Structure data | PDB-7ewh: |
Chemicals | ChemComp-HMT: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / inhibitor |