EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ジャーナル・号・ページ	ACS Med Chem Lett, Vol. 9, Page 929-934, Year 2018
掲載日	2015年10月29日 (構造データの登録日)
著者	Zhu, J. / Dong, J. / Batiste, L. / Unzue, A. / Dolbois, A. / Pascanu, V. / Sledz, P. / Nevado, C. / Caflisch, A.
リンク	ACS Med Chem Lett / PubMed:30258543
手法	X線回折
解像度	1.198 - 2.1 Å
構造データ	PDB-5eic: Crystal structure of the bromodomain of human CREBBP in complex with AYC 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-5eng: Crystal structure of the bromodomain of human CREBBP in complex with UP39 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å PDB-5ep7: Crystal structure of the bromodomain of human CREBBP in complex with UN32 手法: X-RAY DIFFRACTION / 解像度: 1.198 Å PDB-5h85: Crystal structure of the bromodomain of human CREBBP in complex with UO37D 手法: X-RAY DIFFRACTION / 解像度: 1.701 Å PDB-5mme: Crystal structure of CREBBP bromodomain complexd with US46C 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-5mmg: Crystal structure of CREBBP bromodomain complexed with UT07C 手法: X-RAY DIFFRACTION / 解像度: 1.23 Å PDB-5mpk: Crystal structure of CREBBP bromodomain complexed with DK19 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-5mpn: Crystal structure of CREBBP bromodomain complexed with FA26 手法: X-RAY DIFFRACTION / 解像度: 1.23 Å PDB-5owk: Crystal structure of CREBBP bromodomain complexed with DSPB2A002 手法: X-RAY DIFFRACTION / 解像度: 1.25 Å PDB-6fqo: Crystal structure of CREBBP bromodomain complexd with DT29 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-6fqu: Crystal structure of CREBBP bromodomain complexd with DR09 手法: X-RAY DIFFRACTION / 解像度: 1.43 Å PDB-6fr0: Crystal structure of CREBBP bromodomain complexd with PB08 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-6frf: Crystal structure of CREBBP bromodomain complexd with PA10 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å
化合物	ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル / エチレングリコール ChemComp-5J5: 2-[(chloroacetyl)amino]-5-[(E)-(4-sulfophenyl)diazenyl]benzenesulfonic acid ChemComp-HOH: WATER / 水 ChemComp-5QN: methyl 2-[2-(3,5-dihydro-2~{H}-pyrazin-4-yl)ethoxy]-5-[(5-ethanoyl-2-ethoxy-phenyl)carbamoyl]benzoate ChemComp-5QR: 3-[(1-methyl-6-oxidanylidene-pyridin-3-yl)carbonylamino]benzoic acid ChemComp-5XS: methyl 3-(7~{H}-purin-6-ylcarbamoyl)benzoate ChemComp-8Q6: dimethyl 5-[(5-ethanoyl-2-ethoxy-phenyl)amino]benzene-1,3-dicarboxylate ChemComp-UT0: 1-[4-ethoxy-3-[(1-methylsulfonylindol-6-yl)amino]phenyl]ethanone ChemComp-0BC: ~{N}-(5-ethanoyl-2-ethoxy-phenyl)-3-(2~{H}-1,2,3,4-tetrazol-5-yl)-5-(1,3-thiazol-4-yl)benzamide ChemComp-YE5: 1-[4-ethoxy-3-[3-(2~{H}-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]ethanone ChemComp-7MX: ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate ChemComp-E2T: ~{N}-[3-(2,5-dimethyl-3-oxidanylidene-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide ChemComp-E3B: 1-[3-[3-[3,3-bis(fluoranyl)piperidin-1-yl]phenyl]-4-ethoxy-phenyl]ethanone ChemComp-E3H: ~{N}-[3-(5-ethanoyl-2-ethoxy-phenyl)-5-(2-ethyl-5-methyl-3-oxidanylidene-1,2-oxazol-4-yl)phenyl]furan-2-carboxamide ChemComp-E3T: ~{N}-[3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide
由来	homo sapiens (ヒト)
キーワード	TRANSFERASE (転移酵素) / Transferase-Inhibitor complex / Transcription (転写 (生物学)) / INHIBITOR (酵素阻害剤) / Bromodomain (ブロモドメイン) / CREBBP bromodomain