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-Structure paper
Title | Acquisition of Quaternary Interaction during Lineage Maturation Increases the Potency of an HIV-1 Broadly Neutralizing Antibody |
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Journal, issue, pages | To Be Published |
Publish date | May 3, 2024 (structure data deposition date) |
Authors | Liu Q / Parsons R / Wiehe K / Edwards RJ / Saunders KO / Zhang P / Miao H / Williams W / Huang X / Janowska K ...Liu Q / Parsons R / Wiehe K / Edwards RJ / Saunders KO / Zhang P / Miao H / Williams W / Huang X / Janowska K / Mansouri K / Acharya P / Haynes BF / Lusso P |
External links | Search PubMed |
Methods | EM (single particle) |
Resolution | 10.0 - 13.0 Å |
Structure data | EMDB-44736: HIV Envelope trimer BG505 SOSIP.664 in complex with wild type CH103 antibody EMDB-44738: HIV Envelope BG505 SOSIP.664 in complex with one Fab of CH103 E75K/D76N mutant EMDB-44739: HIV Envelope trimer CH505 SOSIP.664 in complex with wild type CH103 antibody EMDB-44740: HIV Envelope trimer CH505 SOSIP.664 in complex with three CH103 E75K/D76N mutant antibody Fabs |
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