Title | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site |
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Journal, issue, pages | Nature, Vol. 628, Page 212-220, Year 2024 |
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Publish date | Jun 6, 2023 (structure data deposition date) |
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Authors | Shioi T / Hatazawa S / Oya E / Hosoya N / Kobayashi W / Ogasawara M / Kobayashi T / Takizawa Y / Kurumizaka H |
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External links | Nature / Search PubMed |
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Methods | EM (single particle) |
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Resolution | 2.89 - 7.8 Å |
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Structure data | EMDB-36442, PDB-8jnd: The cryo-EM structure of the nonameric RAD51 ring bound to the nucleosome with the linker DNA binding Method: EM (single particle) / Resolution: 3.66 Å EMDB-36443, PDB-8jne: The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome without the linker DNA binding Method: EM (single particle) / Resolution: 4.68 Å EMDB-36444, PDB-8jnf: The cryo-EM structure of the RAD51 filament bound to the nucleosome Method: EM (single particle) / Resolution: 6.91 Å EMDB-38228, PDB-8xbt: The cryo-EM structure of the octameric RAD51 ring bound to the nucleosome with the linker DNA binding Method: EM (single particle) / Resolution: 4.12 Å EMDB-38229, PDB-8xbu: The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome with the linker DNA binding Method: EM (single particle) / Resolution: 4.24 Å EMDB-38230, PDB-8xbv: The cryo-EM structure of the RAD51 L1 and L2 loops bound to the linker DNA with the sticky end of the nucleosome Method: EM (single particle) / Resolution: 7.61 Å EMDB-38231, PDB-8xbw: The cryo-EM structure of the RAD51 N-terminal lobe domain bound to the histone H4 tail of the nucleosome Method: EM (single particle) / Resolution: 2.89 Å EMDB-38233, PDB-8xby: The cryo-EM structure of the RAD51 L1 and L2 loops bound to the linker DNA with the blunt end of the nucleosome Method: EM (single particle) / Resolution: 7.8 Å |
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Source | - homo sapiens (human)
- synthetic construct (others)
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Keywords | DNA BINDING PROTEIN/DNA / Nucleosome / Recombinase / DNA BINDING PROTEIN-DNA Complex |
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