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構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
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IF	>30 >20 >10 >5 all

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Structure paper

タイトル	Principles of human pre-60 biogenesis.
ジャーナル・号・ページ	Science, Vol. 381, Issue 6653, Page eadh3892, Year 2023
掲載日	2023年7月7日
著者	Arnaud Vanden Broeck / Sebastian Klinge /
PubMed 要旨	During the early stages of human large ribosomal subunit (60) biogenesis, an ensemble of assembly factors establishes and fine-tunes the essential RNA functional centers of pre-60 particles by an ...During the early stages of human large ribosomal subunit (60) biogenesis, an ensemble of assembly factors establishes and fine-tunes the essential RNA functional centers of pre-60 particles by an unknown mechanism. Here, we report a series of cryo-electron microscopy structures of human nucleolar and nuclear pre-60 assembly intermediates at resolutions of 2.5 to 3.2 angstroms. These structures show how protein interaction hubs tether assembly factor complexes to nucleolar particles and how guanosine triphosphatases and adenosine triphosphatase couple irreversible nucleotide hydrolysis steps to the installation of functional centers. Nuclear stages highlight how a conserved RNA-processing complex, the rixosome, couples large-scale RNA conformational changes with pre-ribosomal RNA processing by the RNA degradation machinery. Our ensemble of human pre-60 particles provides a rich foundation with which to elucidate the molecular principles of ribosome formation.
リンク	Science / PubMed:37410842
手法	EM (単粒子)
解像度	2.33 - 3.75 Å
構造データ	EMDB-29104: Human nucleolar pre-60S ribosomal subunit (State A1) - Overall map 手法: EM (単粒子) / 解像度: 3.0 Å EMDB-29105: Human nucleolar pre-60S ribosomal subunit (State A2) - Overall map 手法: EM (単粒子) / 解像度: 2.85 Å EMDB-29106: Human nucleolar pre-60S ribosomal subunit (State B1) - Overall map 手法: EM (単粒子) / 解像度: 3.09 Å EMDB-29107: Human nucleolar pre-60S ribosomal subunit (State B2) - Overall map 手法: EM (単粒子) / 解像度: 3.06 Å EMDB-29108: Human nucleolar pre-60S ribosomal subunit (State C1) - Overall map 手法: EM (単粒子) / 解像度: 2.98 Å EMDB-29109: Human nucleolar pre-60S ribosomal subunit (State C2) - Overall map 手法: EM (単粒子) / 解像度: 3.03 Å EMDB-29110: Human nucleolar pre-60S ribosomal subunit (State D1) - Overall map 手法: EM (単粒子) / 解像度: 2.6 Å EMDB-29111: Human nucleolar pre-60S ribosomal subunit (State D2) - Overall map 手法: EM (単粒子) / 解像度: 2.63 Å EMDB-29112: Human nucleolar pre-60S ribosomal subunit (State E) - Overall map 手法: EM (単粒子) / 解像度: 2.75 Å EMDB-29113: Human nucleolar pre-60S ribosomal subunit (State F) - Overall map 手法: EM (単粒子) / 解像度: 2.84 Å EMDB-29114: Human nucleolar pre-60S ribosomal subunit (State G) - Overall map 手法: EM (単粒子) / 解像度: 3.19 Å EMDB-29115: Human nucleolar pre-60S ribosomal subunit (State H) - Overall map 手法: EM (単粒子) / 解像度: 2.96 Å EMDB-29116: Human nuclear pre-60S ribosomal subunit (State I1) - Overall map 手法: EM (単粒子) / 解像度: 2.71 Å EMDB-29117: Human nuclear pre-60S ribosomal subunit (State I2) - Overall map 手法: EM (単粒子) / 解像度: 2.53 Å EMDB-29118: Human nuclear pre-60S ribosomal subunit (State I3) - Overall map 手法: EM (単粒子) / 解像度: 3.05 Å EMDB-29119: Human nuclear pre-60S ribosomal subunit (State J1) - Overall map 手法: EM (単粒子) / 解像度: 2.76 Å EMDB-29120: Human nuclear pre-60S ribosomal subunit (State J2) - Overall map 手法: EM (単粒子) / 解像度: 2.66 Å EMDB-29121: Human nuclear pre-60S ribosomal subunit (State J3) - Overall map 手法: EM (単粒子) / 解像度: 2.99 Å EMDB-29122: Human nuclear pre-60S ribosomal subunit (State K1) - Overall map 手法: EM (単粒子) / 解像度: 2.84 Å EMDB-29123: Human nuclear pre-60S ribosomal subunit (State K2) - Overall map 手法: EM (単粒子) / 解像度: 2.64 Å EMDB-29124: Human nuclear pre-60S ribosomal subunit (State K3) - Overall map 手法: EM (単粒子) / 解像度: 3.05 Å EMDB-29125: Human nuclear pre-60S ribosomal subunit (State L1) - Overall map 手法: EM (単粒子) / 解像度: 2.72 Å EMDB-29126: Human nuclear pre-60S ribosomal subunit (State L2) - Overall map 手法: EM (単粒子) / 解像度: 2.49 Å EMDB-29127: Human nuclear pre-60S ribosomal subunit (State L3) - Overall map 手法: EM (単粒子) / 解像度: 2.83 Å EMDB-29128: Human nucleolar pre-60S ribosomal subunit (States A1,A2 & B1,B2 combined) - Domain VI root helix focused map 手法: EM (単粒子) / 解像度: 3.46 Å EMDB-29129: Human nucleolar pre-60S ribosomal subunit (States A1,A2 & B1,B2 combined) - Domain VI helix 96 focused map 手法: EM (単粒子) / 解像度: 3.07 Å EMDB-29130: Human nucleolar pre-60S ribosomal subunit (State A1) - Domain I focused map 手法: EM (単粒子) / 解像度: 2.87 Å EMDB-29131: Human nucleolar pre-60S ribosomal subunit (State A1) - Domain II focused map 手法: EM (単粒子) / 解像度: 2.87 Å EMDB-29132: Human nucleolar pre-60S ribosomal subunit (State A2) - Domain I focused map 手法: EM (単粒子) / 解像度: 2.73 Å EMDB-29133: Human nucleolar pre-60S ribosomal subunit (State A2) - Domain II focused map 手法: EM (単粒子) / 解像度: 2.73 Å EMDB-29134: Human nucleolar pre-60S ribosomal subunit (States A1,A2 combined) - Domain VI focused map 手法: EM (単粒子) / 解像度: 3.05 Å EMDB-29135: Human nucleolar pre-60S ribosomal subunit (States A1,A2 combined) - ITS2 module focused map 手法: EM (単粒子) / 解像度: 2.87 Å EMDB-29136: Human nucleolar pre-60S ribosomal subunit (State B1) - Domain I focused map 手法: EM (単粒子) / 解像度: 2.93 Å EMDB-29137: Human nucleolar pre-60S ribosomal subunit (State B1) - Domain II focused map 手法: EM (単粒子) / 解像度: 2.94 Å EMDB-29138: Human nucleolar pre-60S ribosomal subunit (State B2) - Domain I focused map 手法: EM (単粒子) / 解像度: 2.87 Å EMDB-29139: Human nucleolar pre-60S ribosomal subunit (State B2) - Domain II focused map 手法: EM (単粒子) / 解像度: 2.89 Å EMDB-29140: Human nucleolar pre-60S ribosomal subunit (States B1,B2 combined) - ITS2 module focused map 手法: EM (単粒子) / 解像度: 3.08 Å EMDB-29141: Human nucleolar pre-60S ribosomal subunit (States B1,B2 combined) - Domain VI focused map 手法: EM (単粒子) / 解像度: 3.31 Å EMDB-29142: Human nucleolar pre-60S ribosomal subunit (States B1,B2 combined) - Domain V & GTPB4 focused map 手法: EM (単粒子) / 解像度: 3.09 Å EMDB-29143: Human nucleolar pre-60S ribosomal subunit (State C1) - Domain I focused map 手法: EM (単粒子) / 解像度: 2.83 Å EMDB-29144: Human nucleolar pre-60S ribosomal subunit (State C1) - Domain II focused map 手法: EM (単粒子) / 解像度: 2.85 Å EMDB-29145: Human nucleolar pre-60S ribosomal subunit (State C2) - Domain I focused map 手法: EM (単粒子) / 解像度: 2.82 Å EMDB-29146: Human nucleolar pre-60S ribosomal subunit (State C2) - Domain II focused map 手法: EM (単粒子) / 解像度: 2.86 Å EMDB-29147: Human nucleolar pre-60S ribosomal subunit (States C1,C2 combined) - ITS2 module focused map 手法: EM (単粒子) / 解像度: 3.02 Å EMDB-29148: Human nucleolar pre-60S ribosomal subunit (States C1,C2 combined) - Domains V-VI focused map 手法: EM (単粒子) / 解像度: 2.77 Å EMDB-29149: Human nucleolar pre-60S ribosomal subunit (States C1,C2 combined) - DDX54 focused map 手法: EM (単粒子) / 解像度: 2.97 Å EMDB-29150: Human nucleolar pre-60S ribosomal subunit (States C1,C2 combined) - L1 stalk focused map 手法: EM (単粒子) / 解像度: 3.61 Å EMDB-29151: Human nucleolar pre-60S ribosomal subunit (States A-F combined) - uL15 focused map 手法: EM (単粒子) / 解像度: 2.78 Å EMDB-29152: Human nucleolar pre-60S ribosomal subunit (State D1) - Domain I focused map 手法: EM (単粒子) / 解像度: 2.48 Å EMDB-29153: Human nucleolar pre-60S ribosomal subunit (State D1), Domain II focused map 手法: EM (単粒子) / 解像度: 2.46 Å EMDB-29154: Human nucleolar pre-60S ribosomal subunit (State D1) - Domains V-VI focused map 手法: EM (単粒子) / 解像度: 2.5 Å EMDB-29155: Human nucleolar pre-60S ribosomal subunit (State D1) - GNL3 focused map 手法: EM (単粒子) / 解像度: 2.67 Å EMDB-29156: Human nucleolar pre-60S ribosomal subunit (State D2) - Domain I focused map 手法: EM (単粒子) / 解像度: 2.49 Å EMDB-29157: Human nucleolar pre-60S ribosomal subunit (State D2) - Domain II focused map 手法: EM (単粒子) / 解像度: 2.5 Å EMDB-29158: Human nucleolar pre-60S ribosomal subunit (State D2) - Domains V-VI focused map 手法: EM (単粒子) / 解像度: 2.6 Å EMDB-29159: Human nucleolar pre-60S ribosomal subunit (States D1,D2 combined) - RRS1 focused map 手法: EM (単粒子) / 解像度: 2.33 Å EMDB-29160: Human nucleolar pre-60S ribosomal subunit (States D1,D2 combined) - ITS2 module focused map 手法: EM (単粒子) / 解像度: 2.62 Å EMDB-29161: Human nucleolar pre-60S ribosomal subunit (States D1,D2 combined) - Inter-subunit side focused map 手法: EM (単粒子) / 解像度: 2.67 Å EMDB-29162: Human nucleolar pre-60S ribosomal subunit (States D1,D2 combined) - DDX54 focused map 手法: EM (単粒子) / 解像度: 2.59 Å EMDB-29163: Human nucleolar pre-60S ribosomal subunit (States D1,D2 combined) - L1 stalk focused map 手法: EM (単粒子) / 解像度: 2.78 Å EMDB-29164: Human nucleolar pre-60S ribosomal subunit (States D1,D2 combined) - NOC3L & FTSJ3 focused map 手法: EM (単粒子) / 解像度: 3.19 Å EMDB-29165: Human nucleolar pre-60S ribosomal subunit (States D1,D2 combined) - NOC2L focused map 手法: EM (単粒子) / 解像度: 3.08 Å EMDB-29166: Human nucleolar pre-60S ribosomal subunit (State E) - Domain I focused map 手法: EM (単粒子) / 解像度: 2.58 Å EMDB-29167: Human nucleolar pre-60S ribosomal subunit (State E) - Domain II focused map 手法: EM (単粒子) / 解像度: 2.63 Å EMDB-29168: Human nucleolar pre-60S ribosomal subunit (State E) - ITS2 module focused map 手法: EM (単粒子) / 解像度: 2.97 Å EMDB-29169: Human nucleolar pre-60S ribosomal subunit (State F) - PeBoW-WDR55 focused map 手法: EM (単粒子) / 解像度: 3.04 Å EMDB-29170: Human nucleolar pre-60S ribosomal subunit (State F) - PeBoW complex focused map 手法: EM (単粒子) / 解像度: 3.06 Å EMDB-29171: Human nucleolar pre-60S ribosomal subunit (State F) - WDR55 focused map 手法: EM (単粒子) / 解像度: 3.5 Å EMDB-29173: Human nucleolar pre-60S ribosomal subunit (State F) - Domain III focused map 手法: EM (単粒子) / 解像度: 2.84 Å EMDB-29174: Human nucleolar pre-60S ribosomal subunit (State F) - ITS2 module focused map 手法: EM (単粒子) / 解像度: 2.91 Å EMDB-29175: Human nucleolar pre-60S ribosomal subunit (State F) - Domain I focused map 手法: EM (単粒子) / 解像度: 2.71 Å EMDB-29176: Human nucleolar pre-60S ribosomal subunit (State F) - Domain II focused map 手法: EM (単粒子) / 解像度: 2.68 Å EMDB-29177: Human nucleolar pre-60S ribosomal subunit (States E,F combined) - Inter-subunit side focused map 手法: EM (単粒子) / 解像度: 2.86 Å EMDB-29178: Human nucleolar pre-60S ribosomal subunit (States E,F combined) - DDX54 focused map 手法: EM (単粒子) / 解像度: 2.79 Å EMDB-29179: Human nucleolar pre-60S ribosomal subunit (States E,F combined) - L1 stalk focused map 手法: EM (単粒子) / 解像度: 2.92 Å EMDB-29180: Human nucleolar pre-60S ribosomal subunit (States E,F combined) - NOC3L focused map 手法: EM (単粒子) / 解像度: 3.07 Å EMDB-29181: Human nucleolar pre-60S ribosomal subunit (States E,F combined) - Domain VI focused map 手法: EM (単粒子) / 解像度: 2.58 Å EMDB-29182: Human nucleolar pre-60S ribosomal subunit (States E,F combined) - DDX18 focused map 手法: EM (単粒子) / 解像度: 2.56 Å EMDB-29183: Human nucleolar pre-60S ribosomal subunit (States E,F combined) - Domain V focused map 手法: EM (単粒子) / 解像度: 2.58 Å EMDB-29184: Human nucleolar pre-60S ribosomal subunit (States E,F combined) - RRS1 focused map 手法: EM (単粒子) / 解像度: 2.61 Å EMDB-29185: Human nucleolar pre-60S ribosomal subunit (States E,F combined) - NOC2L focused map 手法: EM (単粒子) / 解像度: 3.75 Å EMDB-29186: Human nucleolar pre-60S ribosomal subunit (State G) - ITS2 module focused map 手法: EM (単粒子) / 解像度: 3.35 Å EMDB-29187: Human nucleolar pre-60S ribosomal subunit (State G) - Domain I focused map 手法: EM (単粒子) / 解像度: 3.06 Å EMDB-29188: Human nucleolar pre-60S ribosomal subunit (State G) - Domain II focused map 手法: EM (単粒子) / 解像度: 3.07 Å EMDB-29189: Human nucleolar pre-60S ribosomal subunit (State G) - Domains V-VI focused map 手法: EM (単粒子) / 解像度: 3.13 Å EMDB-29192: Human nucleolar pre-60S ribosomal subunit (State G) - Domain IV focused map 手法: EM (単粒子) / 解像度: 3.1 Å EMDB-29193: Human nucleolar pre-60S ribosomal subunit (State H) - 5S RNP focused map 手法: EM (単粒子) / 解像度: 2.88 Å EMDB-29194: Human nucleolar pre-60S ribosomal subunit (State H) - Domains V-VI focused map 手法: EM (単粒子) / 解像度: 3.0 Å EMDB-29195: Human nuclear pre-60S ribosomal subunit (States I1,I2,I3 combined) - Central protuberance focused map 手法: EM (単粒子) / 解像度: 2.67 Å EMDB-29196: Human nuclear pre-60S ribosomal subunit (States I1,I2,I3 combined) - TEX10 focused map 手法: EM (単粒子) / 解像度: 2.99 Å EMDB-29197: Human nuclear pre-60S ribosomal subunit (States I1,I2,I3 combined) - Rix1 complex focused map 手法: EM (単粒子) / 解像度: 2.87 Å EMDB-29198: Human nuclear pre-60S ribosomal subunit (States I1,J1,K1,L1 combined) - ITS2 module focused map 手法: EM (単粒子) / 解像度: 2.47 Å EMDB-29199: Human nuclear pre-60S ribosomal subunit (States I2,J2,K2,L2 combined) - ITS2 module focused map 手法: EM (単粒子) / 解像度: 2.39 Å EMDB-29200: Human nuclear pre-60S ribosomal subunit (States J1,J2,J3 combined) - Central protuberance focused map 手法: EM (単粒子) / 解像度: 2.52 Å EMDB-29201: Human nuclear pre-60S ribosomal subunit (States J1,J2,J3 combined) - Domain V focused map 手法: EM (単粒子) / 解像度: 2.59 Å EMDB-29202: Human nuclear pre-60S ribosomal subunit (States K1,K2,K3 combined) - Central protuberance focused map 手法: EM (単粒子) / 解像度: 2.51 Å EMDB-29204: Human nuclear pre-60S ribosomal subunit (States K1,K2,K3 combined) - Domain V focused map 手法: EM (単粒子) / 解像度: 2.58 Å EMDB-29205: Human nuclear pre-60S ribosomal subunit (States L1,L2,L3 combined) - Central protuberance focused map 手法: EM (単粒子) / 解像度: 2.45 Å EMDB-29206: Human nuclear pre-60S ribosomal subunit (States L1,L2,L3 combined) - Domain V focused map 手法: EM (単粒子) / 解像度: 2.52 Å 29252 8fkp EMDB-29252: Human nucleolar pre-60S ribosomal subunit (State A1) - Composite map PDB-8fkp: Human nucleolar pre-60S ribosomal subunit (State A1) 手法: EM (単粒子) / 解像度: 2.85 Å 29253 8fkq EMDB-29253: Human nucleolar pre-60S ribosomal subunit (State A2) - Composite map PDB-8fkq: Human nucleolar pre-60S ribosomal subunit (State A2) 手法: EM (単粒子) / 解像度: 2.76 Å 29254 8fkr EMDB-29254: Human nucleolar pre-60S ribosomal subunit (State B1) - Composite map PDB-8fkr: Human nucleolar pre-60S ribosomal subunit (State B1) 手法: EM (単粒子) / 解像度: 2.89 Å 29255 8fks EMDB-29255: Human nucleolar pre-60S ribosomal subunit (State B2) - Composite map PDB-8fks: Human nucleolar pre-60S ribosomal subunit (State B2) 手法: EM (単粒子) / 解像度: 2.88 Å 29256 8fkt EMDB-29256: Human nucleolar pre-60S ribosomal subunit (State C1) - Composite map PDB-8fkt: Human nucleolar pre-60S ribosomal subunit (State C1) 手法: EM (単粒子) / 解像度: 2.81 Å 29257 8fku EMDB-29257: Human nucleolar pre-60S ribosomal subunit (State C2) - Composite map PDB-8fku: Human nucleolar pre-60S ribosomal subunit (State C2) 手法: EM (単粒子) / 解像度: 2.82 Å 29258 8fkv EMDB-29258: Human nucleolar pre-60S ribosomal subunit (State D1) - Composite map PDB-8fkv: Human nucleolar pre-60S ribosomal subunit (State D1) 手法: EM (単粒子) / 解像度: 2.47 Å 29259 8fkw EMDB-29259: Human nucleolar pre-60S ribosomal subunit (State D2) - Composite map PDB-8fkw: Human nucleolar pre-60S ribosomal subunit (State D2) 手法: EM (単粒子) / 解像度: 2.5 Å 29260 8fkx EMDB-29260: Human nucleolar pre-60S ribosomal subunit (State E) - Composite map PDB-8fkx: Human nucleolar pre-60S ribosomal subunit (State E) 手法: EM (単粒子) / 解像度: 2.59 Å 29261 8fky EMDB-29261: Human nucleolar pre-60S ribosomal subunit (State F) - Composite map PDB-8fky: Human nucleolar pre-60S ribosomal subunit (State F) 手法: EM (単粒子) / 解像度: 2.67 Å 29262 8fkz EMDB-29262: Human nucleolar pre-60S ribosomal subunit (State G) - Composite map PDB-8fkz: Human nucleolar pre-60S ribosomal subunit (State G) 手法: EM (単粒子) / 解像度: 3.04 Å 29263 8fl0 EMDB-29263: Human nucleolar pre-60S ribosomal subunit (State H) - Composite map PDB-8fl0: Human nucleolar pre-60S ribosomal subunit (State H) 手法: EM (単粒子) / 解像度: 2.91 Å 29265 8fl2 EMDB-29265: Human nuclear pre-60S ribosomal subunit (State I1) - Composite map PDB-8fl2: Human nuclear pre-60S ribosomal subunit (State I1) 手法: EM (単粒子) / 解像度: 2.67 Å 29266 8fl3 EMDB-29266: Human nuclear pre-60S ribosomal subunit (State I2) - Composite map PDB-8fl3: Human nuclear pre-60S ribosomal subunit (State I2) 手法: EM (単粒子) / 解像度: 2.53 Å 29267 8fl4 EMDB-29267: Human nuclear pre-60S ribosomal subunit (State I3) - Composite map PDB-8fl4: Human nuclear pre-60S ribosomal subunit (State I3) 手法: EM (単粒子) / 解像度: 2.89 Å 29268 8fl6 EMDB-29268: Human nuclear pre-60S ribosomal subunit (State J1) - Composite map PDB-8fl6: Human nuclear pre-60S ribosomal subunit (State J1) 手法: EM (単粒子) / 解像度: 2.62 Å 29269 8fl7 EMDB-29269: Human nuclear pre-60S ribosomal subunit (State J2) - Composite map PDB-8fl7: Human nuclear pre-60S ribosomal subunit (State J2) 手法: EM (単粒子) / 解像度: 2.55 Å 29271 8fl9 EMDB-29271: Human nuclear pre-60S ribosomal subunit (State J3) - Composite map PDB-8fl9: Human nuclear pre-60S ribosomal subunit (State J3) 手法: EM (単粒子) / 解像度: 2.75 Å 29272 8fla EMDB-29272: Human nuclear pre-60S ribosomal subunit (State K1) - Composite map PDB-8fla: Human nuclear pre-60S ribosomal subunit (State K1) 手法: EM (単粒子) / 解像度: 2.63 Å 29273 8flb EMDB-29273: Human nuclear pre-60S ribosomal subunit (State K2) - Composite map PDB-8flb: Human nuclear pre-60S ribosomal subunit (State K2) 手法: EM (単粒子) / 解像度: 2.55 Å 29274 8flc EMDB-29274: Human nuclear pre-60S ribosomal subunit (State K3) - Composite map PDB-8flc: Human nuclear pre-60S ribosomal subunit (State K3) 手法: EM (単粒子) / 解像度: 2.76 Å 29275 8fld EMDB-29275: Human nuclear pre-60S ribosomal subunit (State L1) - Composite map PDB-8fld: Human nuclear pre-60S ribosomal subunit (State L1) 手法: EM (単粒子) / 解像度: 2.58 Å 29276 8fle EMDB-29276: Human nuclear pre-60S ribosomal subunit (State L2) - Composite map PDB-8fle: Human nuclear pre-60S ribosomal subunit (State L2) 手法: EM (単粒子) / 解像度: 2.48 Å 29277 8flf EMDB-29277: Human nuclear pre-60S ribosomal subunit (State L3) - Composite map PDB-8flf: Human nuclear pre-60S ribosomal subunit (State L3) 手法: EM (単粒子) / 解像度: 2.65 Å
化合物	ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-ZN: Unknown entry ChemComp-SF4: IRON/SULFUR CLUSTER / 鉄・硫黄クラスター ChemComp-GDP: GUANOSINE-5'-DIPHOSPHATE / GDP / GDP, エネルギー貯蔵分子YM / グアノシン二リン酸 ChemComp-K: Unknown entry / カリウムカチオン ChemComp-ADP: ADENOSINE-5'-DIPHOSPHATE / ADP / ADP, エネルギー貯蔵分子YM / アデノシン二リン酸 ChemComp-GTP: GUANOSINE-5'-TRIPHOSPHATE / GTP / GTP, エネルギー貯蔵分子*YM / グアノシン三リン酸
由来	homo sapiens (ヒト) human (ヒト)
キーワード	RIBOSOME (リボソーム) / Pre-60S ribosomal subunit / Assembly intermediate / Nucleoprotein complex (核タンパク質)

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

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2019年1月31日: EMDBのIDの桁数の変更

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2017年7月12日: PDB大規模アップデート

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万見文献

EMDB/PDB/SASBDBから引用されている文献のデータベース

EMDB/PDB/SASBDBのエントリから引用されている文献のデータベースです
Pubmedのデータを利用しています

関連情報:EMDB / PDB / SASBDB / 万見 (Yorodumi) / EMN文献 / 新しいEM Navigatorと万見の変更点

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